Toxins, Volume 15, Issue 12
December 2023 - 37 articles
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Cover Story: Ascochyta fabae poses a global threat to faba beans. We aimed to explore the potential role of secondary metabolites in symptom development, its ability to produce phytotoxins. Cultured in Czapek-Dox, PDB, and rice substrates, the fungus produced metabolites analyzed using NMR and LC-HRMS methods, revealing seven metabolites varying according to cultural substrates. Phytotoxicity assessments on primary hosts showed that Vicia spp. were particularly susceptible, with faba bean vulnerable to all crude exudates and metabolites, especially at higher concentrations. Notably, ascosalitoxin and benzoic acid exhibited the highest phytotoxicity, suggesting a significant role in necrosis development. View this paper