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Review
Peer-Review Record

The Role of Fecal Microbiota Transplantation in IBD

Microorganisms 2024, 12(9), 1755; https://doi.org/10.3390/microorganisms12091755
by Fabrizio Fanizzi 1, Ferdinando D’Amico 1, Isadora Zanotelli Bombassaro 2, Alessandra Zilli 1, Federica Furfaro 1, Tommaso Lorenzo Parigi 1, Clelia Cicerone 1, Gionata Fiorino 3, Laurent Peyrin-Biroulet 4,5,6,7,8,9, Silvio Danese 1 and Mariangela Allocca 1,*
Reviewer 1: Anonymous
Reviewer 2:
Microorganisms 2024, 12(9), 1755; https://doi.org/10.3390/microorganisms12091755
Submission received: 7 August 2024 / Revised: 19 August 2024 / Accepted: 22 August 2024 / Published: 23 August 2024
(This article belongs to the Special Issue Intestinal Dysbiosis)

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

In the attachment

Comments for author File: Comments.pdf

Comments on the Quality of English Language

Minor editing of English language required.

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

The review paper by Fabrizio Fanizzi is informative and interesting. I have the following questions and comments:

1, the figure legend of Figure 1 and Figure 2 are the same. Please revise. 

2, line 115, should be "either as a stand-alone therapy ".

3, why FMT in IBD has not matched the clear efficacy observed in treating CDI? The authors should further discuss the underlying mechanisms. In my opinion, gut dysbiosis is only one contributor to the development of IBD, but for CDI, it is almost the only contributor.

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Round 2

Reviewer 2 Report

Comments and Suggestions for Authors

The authors have revised the manuscript accordingly. It can be considered for publication. 

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