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Microorganisms, Volume 9, Issue 8

2021 August - 248 articles

Cover Story: We speculated whether SARS-CoV-2 interference in the hematopoietic progenitor differentiation process could be the cause of thrombotic events in either COVID-19 patients or vaccinated individuals. The premises are: (i) the subversive activity perpetrated by the SARS-CoV-2 virus inside targeted CD34+ hemopoietic stem cells at the very beginning of the differentiation phase towards the myeloid lineage red cells and platelets. (ii) The presence of different single nucleotide polymorphisms (SNPs) in the individual’s genetic make-up that involve genes regulating immune system responses and genes controlling the coagulation mechanism. View this paper.
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Articles (248)

  • Article
  • Open Access
13 Citations
4,115 Views
20 Pages

Remediation Strategies to Control Toxic Cyanobacterial Blooms: Effects of Macrophyte Aqueous Extracts on Microcystis aeruginosa (Growth, Toxin Production and Oxidative Stress Response) and on Bacterial Ectoenzymatic Activities

  • Zakaria Tazart,
  • Maura Manganelli,
  • Simona Scardala,
  • Franca Maria Buratti,
  • Federica Nigro Di Gregorio,
  • Mountasser Douma,
  • Khadija Mouhri,
  • Emanuela Testai and
  • Mohammed Loudiki

Increasing toxic cyanobacterial blooms in freshwater demand environmentally friendly solutions to control their growth and toxicity, especially in arid countries, where most drinking water is produced from surface reservoirs. We tested the effects of...

  • Article
  • Open Access
3 Citations
2,712 Views
13 Pages

The main goal of this paper was to assess the ability of a combination of Candida boidinii and Bacillus pumilus to remove phenol in table olive processing water, as a function of some variables, like temperature, pH, a dilution of waste and the order...

  • Article
  • Open Access
32 Citations
6,696 Views
15 Pages

HERV-K Modulates the Immune Response in ALS Patients

  • Giannina Arru,
  • Grazia Galleri,
  • Giovanni A. Deiana,
  • Ignazio R. Zarbo,
  • Elia Sechi,
  • Marco Bo,
  • Maria Piera L. Cadoni,
  • Davide G. Corda,
  • Claudia Frau and
  • Leonardo A. Sechi
  • + 6 authors

Human endogenous retrovirus (HERV)-K env-su glycoprotein has been documented in amyotrophic lateral sclerosis (ALS), where HERV-K env-su 19–37 antibody levels significantly correlated with clinical measures of disease severity. Herein, we investigate...

  • Article
  • Open Access
3 Citations
3,113 Views
15 Pages

Root-Associated Microbiomes, Growth and Health of Ornamental Geophytes Treated with Commercial Plant Growth-Promoting Products

  • Gavriel Friesem,
  • Noam Reznik,
  • Michal Sharon Cohen,
  • Nir Carmi,
  • Zohar Kerem and
  • Iris Yedidia

The microbial community inhabiting a plant’s root zone plays a crucial role in plant health and protection. To assess the ability of commercial plant growth-promoting products to enhance the positive effects of this environment, two products containi...

  • Review
  • Open Access
44 Citations
13,170 Views
30 Pages

Hepatitis B Virus DNA Integration, Chronic Infections and Hepatocellular Carcinoma

  • Maria Bousali,
  • George Papatheodoridis,
  • Dimitrios Paraskevis and
  • Timokratis Karamitros

Hepatitis B Virus (HBV) is an Old World virus with a high mutation rate, which puts its origins in Africa alongside the origins of Homo sapiens, and is a member of the Hepadnaviridae family that is characterized by a unique viral replication cycle. I...

  • Article
  • Open Access
23 Citations
4,884 Views
14 Pages

Effects of Age, Diet CP, NDF, EE, and Starch on the Rumen Bacteria Community and Function in Dairy Cattle

  • Yangyi Hao,
  • Yue Gong,
  • Shuai Huang,
  • Shoukun Ji,
  • Wei Wang,
  • Yajing Wang,
  • Hongjian Yang,
  • Zhijun Cao and
  • Shengli Li

To understand the effects of diet and age on the rumen bacterial community and function, forty-eight dairy cattle at 1.5 (M1.5), 6 (M6), 9 (M9), 18 (M18), 23 (M23), and 27 (M27) months old were selected. Rumen fermentation profile, enzyme activity, a...

  • Article
  • Open Access
37 Citations
5,798 Views
16 Pages

Assessment of Carbon Substrate Catabolism Pattern and Functional Metabolic Pathway for Microbiota of Limestone Caves

  • Suprokash Koner,
  • Jung-Sheng Chen,
  • Bing-Mu Hsu,
  • Chao-Wen Tan,
  • Cheng-Wei Fan,
  • Tsung-Hsien Chen,
  • Bashir Hussain and
  • Viji Nagarajan

Carbon utilization of bacterial communities is a key factor of the biomineralization process in limestone-rich curst areas. An efficient carbon catabolism of the microbial community is associated with the availability of carbon sources in such an eco...

  • Article
  • Open Access
12 Citations
4,516 Views
9 Pages

Rational Design for Enhanced Acyltransferase Activity in Water Catalyzed by the Pyrobaculum calidifontis VA1 Esterase

  • Amanda Staudt,
  • Henrik Terholsen,
  • Jasmin Kaur,
  • Henrik Müller,
  • Simon P. Godehard,
  • Ivaldo Itabaiana,
  • Ivana C. R. Leal and
  • Uwe T. Bornscheuer

Biocatalytic transesterification is commonly carried out employing lipases in anhydrous organic solvents since hydrolases usually prefer hydrolysis over acyl transfer in bulk water. However, some promiscuous acyltransferases can catalyze acylation in...

  • Article
  • Open Access
23 Citations
5,281 Views
18 Pages

Fruit flies including Bactrocera zonata and B. dorsalis (Diptera: Tephritidae) are considered major pests of orchard systems in Pakistan. This study evaluated the laboratory virulence, sub-lethal effects, horizontal transmission, greenhouse, and fiel...

  • Article
  • Open Access
8 Citations
4,298 Views
18 Pages

MDR and Pre-XDR Clinical Mycobacterium tuberculosis Beijing Strains: Assessment of Virulence and Host Cytokine Response in Mice Infectious Model

  • Mikhail V. Fursov,
  • Egor A. Shitikov,
  • Denis A. Lagutkin,
  • Anastasiia D. Fursova,
  • Elena A. Ganina,
  • Tatiana I. Kombarova,
  • Natalia S. Grishenko,
  • Tatiana I. Rudnitskaya,
  • Dmitry A. Bespiatykh and
  • Ivan A. Dyatlov
  • + 9 authors

Mycobacterium tuberculosis Beijing genotype associated with drug resistance is a growing public health problem worldwide. The aim of this study was the assessment of virulence for C57BL/6 mice after infection by clinical M. tuberculosis strains 267/4...

  • Article
  • Open Access
4 Citations
3,031 Views
10 Pages

Intestinal Colonization with Tropheryma whipplei—Clinical and Immunological Implications for HIV Positive Adults in Ghana

  • Kirsten Alexandra Eberhardt,
  • Fred Stephen Sarfo,
  • Eva-Maria Klupp,
  • Albert Dompreh,
  • Veronica Di Cristanziano,
  • Edmund Osei Kuffour,
  • Richard Boateng,
  • Betty Norman,
  • Richard Odame Phillips and
  • Torsten Feldt
  • + 1 author

Background: Recent studies demonstrated higher prevalence rates of Tropheryma whipplei (T. whipplei) in HIV positive than in HIV negative subjects. However, associations with the immune status in HIV positive participants were conflicting. Methods: F...

  • Article
  • Open Access
17 Citations
5,830 Views
20 Pages

From Water into Sediment—Tracing Freshwater Cyanobacteria via DNA Analyses

  • Ebuka Canisius Nwosu,
  • Patricia Roeser,
  • Sizhong Yang,
  • Lars Ganzert,
  • Olaf Dellwig,
  • Sylvia Pinkerneil,
  • Achim Brauer,
  • Elke Dittmann,
  • Dirk Wagner and
  • Susanne Liebner

Sedimentary ancient DNA-based studies have been used to probe centuries of climate and environmental changes and how they affected cyanobacterial assemblages in temperate lakes. Due to cyanobacteria containing potential bloom-forming and toxin-produc...

  • Article
  • Open Access
11 Citations
3,162 Views
11 Pages

Antimicrobial Peptide L18R Displays a Modulating Action against Inter-Kingdom Biofilms in the Lubbock Chronic Wound Biofilm Model

  • Paola Di Fermo,
  • Tecla Ciociola,
  • Silvia Di Lodovico,
  • Simonetta D’Ercole,
  • Morena Petrini,
  • Laura Giovati,
  • Stefania Conti,
  • Mara Di Giulio and
  • Luigina Cellini

Chronic wound infections represent an important health problem due to the reduced response to antimicrobial treatment of the pathogens organized in structured biofilms. This study investigated the effects of the previously described antifungal peptid...

  • Article
  • Open Access
5 Citations
3,388 Views
17 Pages

Bioinformatics Investigations of Universal Stress Proteins from Mercury-Methylating Desulfovibrionaceae

  • Raphael D. Isokpehi,
  • Dominique S. McInnis,
  • Antoinette M. Destefano,
  • Gabrielle S. Johnson,
  • Akimio D. Walker,
  • Yessenia A. Hall,
  • Baraka W. Mapp,
  • Matilda O. Johnson and
  • Shaneka S. Simmons

The presence of methylmercury in aquatic environments and marine food sources is of global concern. The chemical reaction for the addition of a methyl group to inorganic mercury occurs in diverse bacterial taxonomic groups including the Gram-negative...

  • Article
  • Open Access
2 Citations
2,682 Views
11 Pages

Latin American Origin Is Not Associated with Worse Outcomes among Hospitalized Patients with COVID-19 in a Public Healthcare System

  • Silvia Otero-Rodriguez,
  • Oscar Moreno-Pérez,
  • Jose Manuel Ramos,
  • Mar García,
  • Vicente Boix,
  • Sergio Reus,
  • Diego Torrus,
  • Pablo Chico-Sánchez,
  • José Sánchez-Payá and
  • on behalf of COVID19 ALC Research Group
  • + 4 authors

Exploring differences in clinical outcomes based on race and origin among patients hospitalized for COVID-19 is a controversial issue. The ALC COVID-19 Registry includes all confirmed COVID-19 patients admitted to hospital from 3 March 2020 to 17 Dec...

  • Review
  • Open Access
48 Citations
5,474 Views
14 Pages

Introduction. It is known that bacterial infections represent a common complication during viral respiratory tract infections such as influenza, with a concomitant increase in morbidity and mortality. Nevertheless, the prevalence of bacterial co-infe...

  • Article
  • Open Access
9 Citations
3,664 Views
14 Pages

The elderly and adults with medical risk conditions remain at high risk of invasive pneumococcal disease (IPD), highlighting the importance of adequate preventive efforts. In an observational population-based study in Norway (pop ≥ 5 years, 2009–2017...

  • Article
  • Open Access
18 Citations
8,345 Views
13 Pages

Comparative Pan-Genome Analysis of Oral Veillonella Species

  • Izumi Mashima,
  • Yu-Chieh Liao,
  • Chieh-Hua Lin,
  • Futoshi Nakazawa,
  • Elaine M. Haase,
  • Yusuke Kiyoura and
  • Frank A. Scannapieco

The genus Veillonella is a common and abundant member of the oral microbiome. It includes eight species, V. atypica, V. denticariosi, V. dispar, V. infantium, V. nakazawae, V. parvula, V. rogosae and V. tobetusensis. They possess important metabolic...

  • Article
  • Open Access
24 Citations
4,650 Views
18 Pages

Hybridized Zoonotic Schistosoma Infections Result in Hybridized Morbidity Profiles: A Clinical Morbidity Study amongst Co-Infected Human Populations of Senegal

  • Cheikh B. Fall,
  • Sébastien Lambert,
  • Elsa Léger,
  • Lucy Yasenev,
  • Amadou Djirmay Garba,
  • Samba D. Diop,
  • Anna Borlase,
  • Stefano Catalano,
  • Babacar Faye and
  • Joanne P. Webster
  • + 2 authors

Hybridization of infectious agents is a major emerging public and veterinary health concern at the interface of evolution, epidemiology, and control. Whilst evidence of the extent of hybridization amongst parasites is increasing, their impact on morb...

  • Article
  • Open Access
13 Citations
4,213 Views
19 Pages

Features of the Opportunistic Behaviour of the Marine Bacterium Marinobacter algicola in the Microalga Ostreococcus tauri Phycosphere

  • Jordan Pinto,
  • Raphaël Lami,
  • Marc Krasovec,
  • Régis Grimaud,
  • Laurent Urios,
  • Josselin Lupette,
  • Marie-Line Escande,
  • Frédéric Sanchez,
  • Laurent Intertaglia and
  • Sophie Sanchez-Brosseau
  • + 2 authors

Although interactions between microalgae and bacteria are observed in both natural environment and the laboratory, the modalities of coexistence of bacteria inside microalgae phycospheres in laboratory cultures are mostly unknown. Here, we focused on...

  • Article
  • Open Access
12 Citations
3,075 Views
8 Pages

Toxocara Seroprevalence and Risk Factor Analysis in Four Communities of the Wiwa, an Indigenous Tribe in Colombia

  • Patrick Waindok,
  • Simone Kann,
  • Andrés Aristizabal,
  • Juan Carlos Dib and
  • Christina Strube

The life of the indigenous Wiwa tribe in northeast Colombia is characterized by lacking access to clean drinking water and sanitary installations. Furthermore, free-roaming domestic animals and use of yucca and/or manioc as a primary food source favo...

  • Article
  • Open Access
23 Citations
3,372 Views
17 Pages

Enterococcus faecium HDRsEf1 (HDRsEf1) was identified to reduce the incidence of diarrhea in weaned piglets, but the mechanism has not been elucidated yet. Based on the fact that gut microbiota plays a crucial role in regulating inflammatory response...

  • Article
  • Open Access
1 Citations
3,123 Views
13 Pages

B7 Family Molecule VSIG4 Regulates Intestinal Anti-Enterohemorrhagic Escherichia coli Immunity by Altering Gut Flora Diversity

  • Zhili He,
  • Jiajia Li,
  • Saisai Gong,
  • Li Xing,
  • Yakun Sun,
  • Jianxin Wang,
  • Tao Li,
  • Nianzhi Ning,
  • Liangyan Zhang and
  • Hui Wang
  • + 2 authors

As an essential member of the B7 family, V-set and immunoglobulin domain-containing 4 (VSIG4) is expressed explicitly in tissue-resident macrophages (TRMs) and plays an essential role in maintaining the homeostasis of the environmental immune system....

  • Article
  • Open Access
40 Citations
4,451 Views
12 Pages

Connection between the Gut Microbiota of Largemouth Bass (Micropterus salmoides) and Microbiota of the Pond Culture Environment

  • Qianfu Liu,
  • Zini Lai,
  • Yuan Gao,
  • Chao Wang,
  • Yanyi Zeng,
  • Erchun Liu,
  • Yongzhan Mai,
  • Wanling Yang and
  • Haiyan Li

The vital role of the gut microbiota in fish growth, development, immunity, and health has been largely confirmed. However, the interaction between environmental microbiota and the gut microbiota of aquaculture species remains unclear. Therefore, we...

  • Review
  • Open Access
79 Citations
13,516 Views
21 Pages

Xylella fastidiosa in Olive: A Review of Control Attempts and Current Management

  • Massimiliano Morelli,
  • José Manuel García-Madero,
  • Ángeles Jos,
  • Pasquale Saldarelli,
  • Crescenza Dongiovanni,
  • Magdalena Kovacova,
  • Maria Saponari,
  • Alberto Baños Arjona,
  • Evelyn Hackl and
  • Stéphane Compant
  • + 1 author

Since 2013, Xylella fastidiosa Wells et al. has been reported to infect several hosts and to be present in different areas of Europe. The main damage has been inflicted on the olive orchards of southern Apulia (Italy), where a severe disease associat...

  • Communication
  • Open Access
14 Citations
3,543 Views
11 Pages

Diversity of Bacillus Isolates from the Sake Brewing Process at a Sake Brewery

  • Emi Kanamoto,
  • Keigo Terashima,
  • Yoshiji Shiraki and
  • Hiromi Nishida

We collected 92 isolates belonging to the genus Bacillus from the sake brewing process at Shiraki Tsunesuke Sake Brewery in Gifu, Japan to determine whether there is strain specificity at individual sake breweries. After distributing the isolates int...

  • Article
  • Open Access
14 Citations
4,860 Views
19 Pages

Pantoea stewartii subsp. indologenes (Psi) is a causative agent of leafspot on foxtail millet and pearl millet; however, novel strains were recently identified that are pathogenic on onions. Our recent host range evaluation study identified two patho...

  • Article
  • Open Access
12 Citations
3,129 Views
14 Pages

Altered Microbial Composition of Drug-Sensitive and Drug-Resistant TB Patients Compared with Healthy Volunteers

  • Fernanda Valdez-Palomares,
  • Marcela Muñoz Torrico,
  • Berenice Palacios-González,
  • Xavier Soberón and
  • Eugenia Silva-Herzog

Mycobacterium tuberculosis infection has three discernible outcomes: active tuberculosis, latent tuberculosis, or clearance of the bacterium. The outcome of the infection depends on the interaction of the bacterium, the immune system, and the microbi...

  • Review
  • Open Access
31 Citations
5,847 Views
28 Pages

Microbiome and Cancers of the Esophagus: A Review

  • Yukiko Yano,
  • Arash Etemadi and
  • Christian C. Abnet

Esophageal cancer (EC) is an aggressive malignant disease ranking amongst the leading causes of cancer deaths in the world. The two main histologic subtypes, esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC), have distinct...

  • Review
  • Open Access
42 Citations
6,390 Views
15 Pages

Update on the Mechanisms of Antibiotic Resistance and the Mobile Resistome in the Emerging Zoonotic Pathogen Streptococcus suis

  • Manon Dechêne-Tempier,
  • Corinne Marois-Créhan,
  • Virginie Libante,
  • Eric Jouy,
  • Nathalie Leblond-Bourget and
  • Sophie Payot

Streptococcus suis is a zoonotic pathogen causing important economic losses in swine production. The most commonly used antibiotics in swine industry are tetracyclines, beta-lactams, and macrolides. Resistance to these antibiotics has already been ob...

  • Article
  • Open Access
12 Citations
4,118 Views
19 Pages

Analysis of Human Gut Microbiota Composition Associated to the Presence of Commensal and Pathogen Microorganisms in Côte d’Ivoire

  • Veronica Di Cristanziano,
  • Fedja Farowski,
  • Federica Berrilli,
  • Maristella Santoro,
  • David Di Cave,
  • Christophe Glé,
  • Martin Daeumer,
  • Alexander Thielen,
  • Maike Wirtz and
  • Rossella D’Alfonso
  • + 3 authors

Background: The human gut microbiota is a microbial ecosystem contributing to the maintenance of host health with functions related to immune and metabolic aspects. Relations between microbiota and enteric pathogens in sub-Saharan Africa are scarcely...

  • Article
  • Open Access
138 Citations
15,781 Views
25 Pages

The Ever-Expanding Pseudomonas Genus: Description of 43 New Species and Partition of the Pseudomonas putida Group

  • Léa Girard,
  • Cédric Lood,
  • Monica Höfte,
  • Peter Vandamme,
  • Hassan Rokni-Zadeh,
  • Vera van Noort,
  • Rob Lavigne and
  • René De Mot

The genus Pseudomonas hosts an extensive genetic diversity and is one of the largest genera among Gram-negative bacteria. Type strains of Pseudomonas are well known to represent only a small fraction of this diversity and the number of available Pseu...

  • Article
  • Open Access
4 Citations
3,449 Views
19 Pages

Nicastrin-Like, a Novel Transmembrane Protein from Trypanosoma cruzi Associated to the Flagellar Pocket

  • Guilherme Curty Lechuga,
  • Paloma Napoleão-Pêgo,
  • Larissa Rodrigues Gomes,
  • Andressa da Matta Durans,
  • David William Provance and
  • Salvatore Giovanni De-Simone

Nicastrin (NICT) is a transmembrane protein physically associated with the polytypical aspartyl protease presenilin that plays a vital role in the correct localization and stabilization of presenilin to the membrane-bound γ-secretase complex. This co...

  • Article
  • Open Access
11 Citations
3,884 Views
12 Pages

Modulation of the Mucosa-Associated Microbiome Linked to the PTPN2 Risk Gene in Patients with Primary Sclerosing Cholangitis and Ulcerative Colitis

  • Luisa Denoth,
  • Pascal Juillerat,
  • Andreas E. Kremer,
  • Gerhard Rogler,
  • Michael Scharl,
  • Bahtiyar Yilmaz,
  • Sena Bluemel and
  • on behalf of the Swiss IBD Cohort Study

Gut microbiota appears to be involved in the pathogenesis of primary sclerosing cholangitis (PSC). The protein tyrosine phosphatase nonreceptor 2 (PTPN2) gene risk variant rs1893217 is associated with gut dysbiosis in inflammatory bowel disease (IBD)...

  • Article
  • Open Access
7 Citations
4,034 Views
11 Pages

First Genome Description of Providencia vermicola Isolate Bearing NDM-1 from Blood Culture

  • David Lupande-Mwenebitu,
  • Mariem Ben Khedher,
  • Sami Khabthani,
  • Lalaoui Rym,
  • Marie-France Phoba,
  • Larbi Zakaria Nabti,
  • Octavie Lunguya-Metila,
  • Alix Pantel,
  • Jean-Philippe Lavigne and
  • Seydina M. Diene
  • + 1 author

In this paper, we describe the first complete genome sequence of Providencia vermicola species, a clinical multidrug-resistant strain harboring the New Delhi Metallo-β-lactamase-1 (NDM-1) gene, isolated at the Kinshasa University Teaching Hospital, i...

  • Article
  • Open Access
5 Citations
3,074 Views
14 Pages

The Upcoming 6Li Isotope Requirements Might Be Supplied by a Microalgal Enrichment Process

  • Héctor M. Díaz-Alejo,
  • Victoria López-Rodas,
  • Camino García-Balboa,
  • Francisco Tarín,
  • Ana I. Barrado,
  • Estefanía Conde and
  • Eduardo Costas

Lithium isotopes are essential for nuclear energy, but new enrichment methods are required. In this study, we considered biotechnology as a possibility. We assessed the Li fractionation capabilities of three Chlorophyte strains: Chlamydomonas reinhar...

  • Article
  • Open Access
6 Citations
3,742 Views
10 Pages

Comparative Genome Analysis Provides Molecular Evidence for Reclassification of the Photosynthetic Bacterium Rhodobacter sphaeroides EBL0706 as a Strain of Luteovulum azotoformans

  • Haoyu Wang,
  • Xiaoling Sha,
  • Rui Li,
  • Yijing Li,
  • Himel Nahreen Khaleque,
  • Yuxiu Zhang,
  • Tsing Bohu,
  • Zhihui Bai and
  • Xuliang Zhuang

In this study, we conducted a genome-wide comparative analysis of a former Rhodobacter sphaeroides strain EBL0706, which is now recorded as Luteovulum sphaeroides EBL0706. The genome of EBL0706 was compared with that of Luteovulum azotoformans ATCC 1...

  • Article
  • Open Access
3 Citations
3,116 Views
9 Pages

Research investigating the gut microbiome (GM) during a viral infection may necessitate inactivation of the fecal viral load. Here, we assess how common viral inactivation techniques affect 16S rRNA-based analysis of the gut microbiome. Five common v...

  • Article
  • Open Access
12 Citations
3,183 Views
17 Pages

SAP11 is an effector protein that has been identified in various phytoplasma species. It localizes in the plant nucleus and can bind and destabilize TEOSINE BRANCHES/CYCLOIDEA/PROLIFERATING CELL FACTOR (TCP) transcription factors. Although SAP11 of d...

  • Article
  • Open Access
19 Citations
3,523 Views
18 Pages

Seasonal Dynamics of Fungi Associated with Healthy and Diseased Pinus sylvestris Needles in Northern Europe

  • Ahto Agan,
  • Halvor Solheim,
  • Kalev Adamson,
  • Ari Mikko Hietala,
  • Leho Tedersoo and
  • Rein Drenkhan

The relationship between the ecological success of needle pathogens of forest trees and species richness of co-inhabiting endophytic fungi is poorly understood. One of the most dangerous foliar pathogens of pine is Dothistroma septosporum, which is a...

  • Review
  • Open Access
15 Citations
6,133 Views
20 Pages

Enterovirus D: A Small but Versatile Species

  • Ines Cordeiro Filipe,
  • Mariana Soares Guedes,
  • Evgeny M. Zdobnov and
  • Caroline Tapparel

Enteroviruses (EVs) from the D species are the causative agents of a diverse range of infectious diseases in spite of comprising only five known members. This small clade has a diverse host range and tissue tropism. It contains types infecting non-hu...

  • Review
  • Open Access
28 Citations
5,953 Views
28 Pages

Degradation of Bile Acids by Soil and Water Bacteria

  • Franziska Maria Feller,
  • Johannes Holert,
  • Onur Yücel and
  • Bodo Philipp

Bile acids are surface-active steroid compounds with a C5 carboxylic side chain at the steroid nucleus. They are produced by vertebrates, mainly functioning as emulsifiers for lipophilic nutrients, as signaling compounds, and as an antimicrobial barr...

  • Article
  • Open Access
8 Citations
5,118 Views
14 Pages

As productive biofilms are increasingly gaining interest in research, the quantitative monitoring of biofilm formation on- or offline for the process remains a challenge. Optical coherence tomography (OCT) is a fast and often used method for scanning...

  • Article
  • Open Access
25 Citations
5,027 Views
13 Pages

SARS-CoV-2 Spike Pseudoviruses: A Useful Tool to Study Virus Entry and Address Emerging Neutralization Escape Phenotypes

  • Raj Kalkeri,
  • Zhaohui Cai,
  • Shuling Lin,
  • John Farmer,
  • Yury V. Kuzmichev and
  • Fusataka Koide

SARS-CoV-2 genetic variants are emerging around the globe. Unfortunately, several SARS-CoV-2 variants, especially variants of concern (VOCs), are less susceptible to neutralization by the convalescent and post-vaccination sera, raising concerns of in...

  • Article
  • Open Access
5 Citations
3,077 Views
12 Pages

Virulence Pattern Analysis of Three Listeria monocytogenes Lineage I Epidemic Strains with Distinct Outbreak Histories

  • Martin Wagner,
  • Jörg Slaghuis,
  • Werner Göbel,
  • José Antonio Vázquez-Boland,
  • Kathrin Rychli and
  • Stephan Schmitz-Esser

Strains of the food-borne pathogen Listeria (L.) monocytogenes have diverse virulence potential. This study focused on the virulence of three outbreak strains: the CC1 strain PF49 (serovar 4b) from a cheese-associated outbreak in Switzerland, the cli...

  • Article
  • Open Access
1 Citations
3,078 Views
10 Pages

Clinical Outcomes of Immunocompromised Adults Hospitalized with Pneumococcal Pneumonia: A Case-Control Study

  • Julio Ramirez,
  • Thomas Chandler,
  • Stephen Furmanek,
  • Forest Arnold and
  • Jose Bordon

S. pneumoniae is a primary etiologic agent of CAP in immunocompromised adults (ICA). Data on clinical outcomes of ICA hospitalized with pneumococcal pneumonia (PP) is limited. The objectives of this study were (1) to define clinical presentation and...

  • Article
  • Open Access
14 Citations
3,623 Views
20 Pages

Role of Rhizospheric Microbiota as a Bioremediation Tool for the Protection of Soil-Plant Systems from Microcystins Phytotoxicity and Mitigating Toxin-Related Health Risk

  • El Mahdi Redouane,
  • Richard Mugani,
  • Majida Lahrouni,
  • José Carlos Martins,
  • Soukaina El Amrani Zerrifi,
  • Khalid Oufdou,
  • Alexandre Campos,
  • Vitor Vasconcelos and
  • Brahim Oudra

Frequent toxic cyanoblooms in eutrophic freshwaters produce various cyanotoxins such as the monocyclic heptapeptides microcystins (MCs), known as deleterious compounds to plant growth and human health. Recently, MCs are a recurrent worldwide sanitary...

  • Article
  • Open Access
10 Citations
3,451 Views
13 Pages

Engagement of CEACAM1 by Helicobacter pylori HopQ Is Important for the Activation of Non-Canonical NF-κB in Gastric Epithelial Cells

  • Karin Taxauer,
  • Youssef Hamway,
  • Anna Ralser,
  • Alisa Dietl,
  • Karin Mink,
  • Michael Vieth,
  • Bernhard B. Singer,
  • Markus Gerhard and
  • Raquel Mejías-Luque

The gastric pathogen Helicobacter pylori infects half of the world’s population and is a major risk factor for gastric cancer development. In order to attach to human gastric epithelial cells and inject the oncoprotein CagA into host cells, H. pylori...

  • Review
  • Open Access
17 Citations
5,292 Views
23 Pages

Congenital cytomegalovirus infection (cCMV) may affect about 1% of all newborns all over the world as a result of either a primary or recurrent human cytomegalovirus (HCMV) infection. While about 90% of infants affected by cCMV are asymptomatic at bi...

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Microorganisms - ISSN 2076-2607