Next Article in Journal
Far and Near Contrast Sensitivity and Quality of Vision with Six Presbyopia Correcting Intraocular Lenses
Previous Article in Journal
Visceral Fat Area Measured by Abdominal Bioelectrical Impedance Analysis in School-Aged Japanese Children
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JCM
Volume 11
Issue 14
10.3390/jcm11144147
jcm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

The Potential Role of Renal Denervation in the Management of Heart Failure

by
Kameel Kassab
1,2,*,
Ronak Soni
1,2,
Adnan Kassier
1,2 and
Tim A. Fischell
1,2
1
Division of Cardiology, Borgess Heart Institute, 1521 Gull Road, Kalamazoo, MI 49048, USA
2
Division of Cardiology, Michigan State University, Kalamazoo, MI 49048, USA
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2022, 11(14), 4147; https://doi.org/10.3390/jcm11144147
Submission received: 16 June 2022 / Revised: 14 July 2022 / Accepted: 15 July 2022 / Published: 17 July 2022
(This article belongs to the Section Cardiovascular Medicine)
Browse Figure
Review Reports Versions Notes

Abstract

Sympathetic nervous system activation in patients with heart failure is one of the main pathophysiologic mechanisms associated with the worse outcomes. Pharmacotherapies targeting neurohormonal activation have been at the center of heart failure management. Despite the advancement of therapies and the available treatments, heart failure continues to have an overall poor prognosis. Renal denervation was originally developed to lower systemic blood pressure in patients with poorly controlled hypertension, by modulating sympathetic outflow. However, more recently, multiple studies have investigated the effect of renal denervation in heart failure patients with both preserved (HFpEF) and reduced ejection fractions (HFrEF). This paper provides an overview of the potential effect of renal denervation in altering the various pathophysiologic, sympathetically mediated pathways that contribute to heart failure, and reviews the literature that supports its future use in those patients.
Keywords: renal denervation; heart failure; therapies renal denervation; heart failure; therapies

Share and Cite

MDPI and ACS Style

Kassab, K.; Soni, R.; Kassier, A.; Fischell, T.A. The Potential Role of Renal Denervation in the Management of Heart Failure. J. Clin. Med. 2022, 11, 4147. https://doi.org/10.3390/jcm11144147

AMA Style

Kassab K, Soni R, Kassier A, Fischell TA. The Potential Role of Renal Denervation in the Management of Heart Failure. Journal of Clinical Medicine. 2022; 11(14):4147. https://doi.org/10.3390/jcm11144147

Chicago/Turabian Style

Kassab, Kameel, Ronak Soni, Adnan Kassier, and Tim A. Fischell. 2022. "The Potential Role of Renal Denervation in the Management of Heart Failure" Journal of Clinical Medicine 11, no. 14: 4147. https://doi.org/10.3390/jcm11144147

APA Style

Kassab, K., Soni, R., Kassier, A., & Fischell, T. A. (2022). The Potential Role of Renal Denervation in the Management of Heart Failure. Journal of Clinical Medicine, 11(14), 4147. https://doi.org/10.3390/jcm11144147

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop