Abstract
Background: Liver cirrhosis presents significant challenges in the pediatric population due to a complex interplay of etiological factors, clinical manifestations, and limited therapeutic options. The leading contributors to cirrhosis among pediatric patients are chronic cholestasis, metabolic disorders present from birth, and long-term hepatitis. Materials and method: Our narrative review aimed to synthesize literature data on the etiology, clinical picture, diagnostic techniques, optimal management of complications, and timely transplantation. Results: The epidemiology of liver cirrhosis in pediatric patients is evolving. The introduction of a universal vaccination and effective long-term viral suppression in viral hepatitis have significantly decreased complications rates. Liver transplantation programs worldwide have also improved the management of cirrhosis complications. Conclusions: Early diagnosis, comprehensive management strategies, and advancements in treatment modalities are critical for improving outcomes. Understanding these differences is crucial in providing age-appropriate care and support for those affected by cirrhosis.
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MDPI and ACS Style
Forna, L.; Bozomitu, L.; Lupu, V.V.; Lupu, A.; Trandafir, L.M.; Adam Raileanu, A.; Cojocariu, C.; Anton, C.; Girleanu, I.; Muzica, C.M.
Pediatric Perspectives on Liver Cirrhosis: Unravelling Clinical Patterns and Therapeutic Challenges. J. Clin. Med. 2024, 13, 4275.
https://doi.org/10.3390/jcm13144275
AMA Style
Forna L, Bozomitu L, Lupu VV, Lupu A, Trandafir LM, Adam Raileanu A, Cojocariu C, Anton C, Girleanu I, Muzica CM.
Pediatric Perspectives on Liver Cirrhosis: Unravelling Clinical Patterns and Therapeutic Challenges. Journal of Clinical Medicine. 2024; 13(14):4275.
https://doi.org/10.3390/jcm13144275
Chicago/Turabian Style
Forna, Lorenza, Laura Bozomitu, Vasile Valeriu Lupu, Ancuta Lupu, Laura Mihaela Trandafir, Anca Adam Raileanu, Camelia Cojocariu, Carmen Anton, Irina Girleanu, and Cristina Maria Muzica.
2024. "Pediatric Perspectives on Liver Cirrhosis: Unravelling Clinical Patterns and Therapeutic Challenges" Journal of Clinical Medicine 13, no. 14: 4275.
https://doi.org/10.3390/jcm13144275
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