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Article

Anodic Production and Characterization of Biomimetic Oxide Layers on Grade 4 Titanium for Medical Applications

Institute of Materials Engineering, Faculty of Science and Technology, University of Silesia in Katowice, 41-500 Chorzow, Poland
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J. Funct. Biomater. 2024, 15(7), 180; https://doi.org/10.3390/jfb15070180
Submission received: 30 April 2024 / Revised: 23 June 2024 / Accepted: 27 June 2024 / Published: 29 June 2024
(This article belongs to the Special Issue Advances in Biomedical Alloys and Surface Modification)

Abstract

Biomaterials are the basis for the development of medicine because they allow safe contact with a living organism. The aim of this work was to produce innovative oxide layers with a microporous structure on the surface of commercially pure titanium Grade 4 (CpTi G4) and to characterize their properties as drug carriers. The anodization of the CpTi G4 subjected to mechanical grinding and electrochemical polishing was carried out in a solution of 1M ethylene glycol with the addition of 40 g of ammonium fluoride at a voltage of 20 V for 2, 18, 24, and 48 h at room temperature. It was found that the longer the anodization time, the greater the number of pores formed on the CpTi G4 surface as revealed using the FE-SEM method, and the greater the surface roughness determined in profilometric tests. As the anodizing time increases, the amount of the drug in the form of gentamicin sulfate incorporated into the resulting pores decreases. The most favorable drug release kinetics profile determined via UV–VIS absorption spectroscopy was found for the CpTi G4 anodized for 2 h.
Keywords: anodization; biomimetics; oxide layer; porous titanium; drug carriers anodization; biomimetics; oxide layer; porous titanium; drug carriers

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MDPI and ACS Style

Nowińska, D.; Osak, P.; Maszybrocka, J.; Łosiewicz, B. Anodic Production and Characterization of Biomimetic Oxide Layers on Grade 4 Titanium for Medical Applications. J. Funct. Biomater. 2024, 15, 180. https://doi.org/10.3390/jfb15070180

AMA Style

Nowińska D, Osak P, Maszybrocka J, Łosiewicz B. Anodic Production and Characterization of Biomimetic Oxide Layers on Grade 4 Titanium for Medical Applications. Journal of Functional Biomaterials. 2024; 15(7):180. https://doi.org/10.3390/jfb15070180

Chicago/Turabian Style

Nowińska, Delfina, Patrycja Osak, Joanna Maszybrocka, and Bożena Łosiewicz. 2024. "Anodic Production and Characterization of Biomimetic Oxide Layers on Grade 4 Titanium for Medical Applications" Journal of Functional Biomaterials 15, no. 7: 180. https://doi.org/10.3390/jfb15070180

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