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Biomolecules
Volume 12
Issue 10
10.3390/biom12101446
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Peer-Review Record

COVID-GWAB: A Web-Based Prediction of COVID-19 Host Genes via Network Boosting of Genome-Wide Association Data

Biomolecules 2022, 12(10), 1446; https://doi.org/10.3390/biom12101446
by Seungbyn Baek 1, Sunmo Yang 1 and Insuk Lee 1,2,*
Reviewer 1:
Mauro Fasano
Reviewer 2:
Tugba Taskin-Tok
Biomolecules 2022, 12(10), 1446; https://doi.org/10.3390/biom12101446
Submission received: 2 September 2022 / Revised: 1 October 2022 / Accepted: 2 October 2022 / Published: 9 October 2022
(This article belongs to the Special Issue Applications of Systems Biology Approaches in Biomedicine)

Round 1

Reviewer 1 Report

Baek and coworkers reported about a web-based tool to prioritize host genes responding to SARS-CoV-2 infection. The approach is original and results are of interest for the scientific community. Altogether, the paper is well written and results are clear to be understood.

 

Minor: please summarize in a table all online resources that have been taken into consideration with their url.

Author Response

Reviewer's commnent:

Baek and coworkers reported about a web-based tool to prioritize host genes responding to SARS-CoV-2 infection. The approach is original and results are of interest for the scientific community. Altogether, the paper is well written and results are clear to be understood.

Thank you for your positive feedback.

Minor: please summarize in a table all online resources that have been taken into consideration with their url.

The only online resource we use for the web tool is COVID-19 Host Genetics Initiative (HGI) and its URL is indicated in the main text (www.covid19hg.org). Therefore, we believe a table for URL information is not necessary.

Reviewer 2 Report

Dear Author,

 

It is very valuable in terms of facilitating the web-based use of experimental data by organizing more effective and appropriate approaches to the important issue you discussed in the study.

It would be good to present the study by considering the places that need to be revised in the English part of the study.

 

Regards

Author Response

Review comments:

It is very valuable in terms of facilitating the web-based use of experimental data by organizing more effective and appropriate approaches to the important issue you discussed in the study.

It would be good to present the study by considering the places that need to be revised in the English part of the study.

Thank you for your positive feedback. To address the reviewer's concern, we had a fluent English writer to revised the manuscript. The revised manuscript with track change is uploaded.

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