Effect of Health Status and Heat-Induced Inactivation on the Proteomic Profile of Plasma Rich in Growth Factors Obtained from Donors with Chronic Inflammatory Skin Conditions
Abstract
:1. Introduction
2. Materials and Methods
2.1. Preparation of PRGF Supernatants
2.2. Immunosafe Treatment
2.3. Proteomic Analysis
2.4. Functional Analyses
3. Results
3.1. Effect of Skin Condition
3.2. Effect of the Immunosafe Treatment
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Study Group | Mean Age (Years) | Sex (Number of Patients) | |
---|---|---|---|
Male | Female | ||
Healthy | 51 (range: 33 to 69) | 2 | 1 |
Atopic Dermatitis | 28 (range: 15 to 52) | 1 | 2 |
Psoriasis | 50 (range: 36 to 65) | 0 | 3 |
Lichen sclerosus | 41 (range: 20 to 61) | 0 | 3 |
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Anitua, E.; Tierno, R.; Azkargorta, M.; Elortza, F.; Alkhraisat, M.H. Effect of Health Status and Heat-Induced Inactivation on the Proteomic Profile of Plasma Rich in Growth Factors Obtained from Donors with Chronic Inflammatory Skin Conditions. Biomolecules 2024, 14, 763. https://doi.org/10.3390/biom14070763
Anitua E, Tierno R, Azkargorta M, Elortza F, Alkhraisat MH. Effect of Health Status and Heat-Induced Inactivation on the Proteomic Profile of Plasma Rich in Growth Factors Obtained from Donors with Chronic Inflammatory Skin Conditions. Biomolecules. 2024; 14(7):763. https://doi.org/10.3390/biom14070763
Chicago/Turabian StyleAnitua, Eduardo, Roberto Tierno, Mikel Azkargorta, Félix Elortza, and Mohammad H. Alkhraisat. 2024. "Effect of Health Status and Heat-Induced Inactivation on the Proteomic Profile of Plasma Rich in Growth Factors Obtained from Donors with Chronic Inflammatory Skin Conditions" Biomolecules 14, no. 7: 763. https://doi.org/10.3390/biom14070763