Contrasting Retromer with a Newly Described Retriever in Arabidopsis thaliana
Abstract
:1. Introduction
2. Fates of Endocytosed Cargo
3. Retromer in Yeast and Mammals
4. Plasma Membrane Protein Recycling by Retromer and Retriever
5. Plant Retromer and Retriever
6. Retromer-Binding Proteins
7. Is There a Retriever Complex in Plants?
8. Genetic Interactions between VTI11- and VTI13-Dependent Pathways to the Lytic Vacuole and Retromer/Retriever Function in Plants
9. Future Directions
- Is retriever involved in the recycling of plasma membrane proteins in plants and what are its cargoes?
- BLISTER and ALIX associate with retromer in Arabidopsis. What other proteins are associated with core retromer and retriever complexes in plants to modify/regulate their function?
- Do CCDC22 and CCDC93 associate with retriever alone or are they also involved in retromer function?
- Do CCDC22 and CCDC93 interact with other protein complexes in plants to compensate for the loss of COMMD proteins in seed plants?
- Are specific versions of the VPS35/29/26 complex required for cell-type-specific endosomal trafficking in plants?
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
Abbreviations
ALIX | Apoptosis-linked gene-2-interacting protein X |
BAR | Bin-Amphiphysin-Rvs |
BLI | BLISTER |
CCDC | Coiled-Coil Domain-Containing |
CI-MPR | Cation-independent mannose 6-phosphate receptor |
CLASP1 | Cytoplasmic linker-associated protein 1 |
COMMD | Commander |
CPY | Carboxypeptidase Y |
DSCR3 | Down syndrome critical region 3 |
EE | Early endosome |
ER | Endoplasmic reticulum |
ESCRT | Endosomal sorting complex required for transport |
FREE1 | FYVE DOMAIN PROTEIN REQUIRED FOR ENDOSOMAL SORTING 1 |
GEF | Guanine nucleotide exchange factor |
GTPase | Guanosine triphosphate-activating protein |
ILV | Intraluminal vesicles |
LE | Late endosome |
MBV | Multivesicular body |
PI3P | Phosphatidylinositol 3-phosphate |
PIN1 | Pin-formed |
RAB | ras-associated binding |
RFP | Red fluorescent protein |
SCAR | Suppressor of cAMP receptor |
SNX | Sorting nexin |
TGN | trans-Golgi network |
VPS | Vacuolar protein sorting |
VSR | Vacuolar sorting receptor |
VTI | VPS10 interacting |
WASH | Wiskott–Aldrich syndrome |
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Lewis, C.D.; Tierney, M.L. Contrasting Retromer with a Newly Described Retriever in Arabidopsis thaliana. Plants 2024, 13, 2470. https://doi.org/10.3390/plants13172470
Lewis CD, Tierney ML. Contrasting Retromer with a Newly Described Retriever in Arabidopsis thaliana. Plants. 2024; 13(17):2470. https://doi.org/10.3390/plants13172470
Chicago/Turabian StyleLewis, Connor D., and Mary L. Tierney. 2024. "Contrasting Retromer with a Newly Described Retriever in Arabidopsis thaliana" Plants 13, no. 17: 2470. https://doi.org/10.3390/plants13172470