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Proteomes, Volume 6, Issue 2

2018 June - 14 articles

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Articles (14)

  • Article
  • Open Access
17 Citations
8,139 Views
34 Pages

Large Scale Proteomic Data and Network-Based Systems Biology Approaches to Explore the Plant World

  • Dario Di Silvestre,
  • Andrea Bergamaschi,
  • Edoardo Bellini and
  • PierLuigi Mauri

The investigation of plant organisms by means of data-derived systems biology approaches based on network modeling is mainly characterized by genomic data, while the potential of proteomics is largely unexplored. This delay is mainly caused by the pa...

  • Feature Paper
  • Review
  • Open Access
29 Citations
6,565 Views
9 Pages

Mycobacterium tuberculosis is one of the deadliest human pathogen of the tuberculosis diseases. Drug resistance leads to emergence of multidrug-resistant and extremely drug resistant strains of M. tuberculosis. Apart from principal targets of resista...

  • Article
  • Open Access
14 Citations
4,738 Views
12 Pages

The rose is one the most commercially grown and costly ornamental plants because of its aesthetic beauty and aroma. A large number of pests attack its buds, flowers, leaves, and stem at every growing stage due to its high sugar content. The most comm...

  • Feature Paper
  • Review
  • Open Access
11 Citations
6,865 Views
9 Pages

Virophages are small dsDNA viruses that were first isolated in association with some giant viruses (GVs), and then found in metagenomics samples. They encode about 20–34 proteins. Some virophages share protein similarity with Maverick/Polinton...

  • Article
  • Open Access
13 Citations
5,882 Views
14 Pages

Post-translational modification (PTM) crosstalk is recognized as a major cell-regulatory mechanism, and studies of several proteins have validated the premise that PTMs work in concert. Previous work by our group investigated the potential PTM crosst...

  • Review
  • Open Access
20 Citations
9,901 Views
12 Pages

Proteomics of Human Retinal Pigment Epithelium (RPE) Cells

  • Sarka Beranova-Giorgianni and
  • Francesco Giorgianni

Retinal pigment epithelium (RPE) are specialized, multifunctional cells in the retina that form a monolayer of cuboidal, polarized cells adjoining the photoreceptor cells. The RPE are a critical component of the blood-retinal barrier, and they play e...

  • Review
  • Open Access
9 Citations
6,066 Views
11 Pages

In many tropical countries with agriculture as the mainstay of the economy, tropical crops are commonly cultivated at the plantation scale. The successful establishment of crop plantations depends on the availability of a large quantity of elite seed...

  • Review
  • Open Access
31 Citations
6,777 Views
17 Pages

Protein biomarkers are of great benefit for clinical research and applications, as they are powerful means for diagnosing, monitoring and treatment prediction of different diseases. Even though numerous biomarkers have been reported, the translation...

  • Article
  • Open Access
11 Citations
5,605 Views
13 Pages

A Proteomic View of Salmonella Typhimurium in Response to Phosphate Limitation

  • Jiezhang Jiang,
  • Kaiwen Yu,
  • Linlu Qi,
  • Yanhua Liu,
  • Sen Cheng,
  • Mei Wu,
  • Zhen Wang,
  • Jiaqi Fu and
  • Xiaoyun Liu

Salmonella enterica serovar Typhimurium (S. Typhimurium), an important foodborne pathogen, often encounters phosphate (Pi) shortage both in the environment and inside host cells. To gain a global view on its physiological responses to Pi starvation,...

  • Feature Paper
  • Article
  • Open Access
16 Citations
6,220 Views
11 Pages

Surface and Extracellular Proteome of the Emerging Pathogen Corynebacterium ulcerans

  • Miriam Bittel,
  • Susanne Gastiger,
  • Bushra Amin,
  • Jörg Hofmann and
  • Andreas Burkovski

Corynebacterium ulcerans is an emerging pathogen, which is increasingly recognized as an etiological agent of diphtheria, but can also evoke ulcers of the skin and systemic infections in humans. Besides man, the bacteria can colonize a wide variety o...

  • Review
  • Open Access
74 Citations
12,770 Views
17 Pages

Molecular Pathophysiology of Epithelial Barrier Dysfunction in Inflammatory Bowel Diseases

  • Jessica Y. Lee,
  • Valerie C. Wasinger,
  • Yunki Y. Yau,
  • Emil Chuang,
  • Vijay Yajnik and
  • Rupert WL. Leong

Over the years, the scientific community has explored myriads of theories in search of the etiology and a cure for inflammatory bowel disease (IBD). The cumulative evidence has pointed to the key role of the intestinal barrier and the breakdown of th...

  • Article
  • Open Access
15 Citations
7,313 Views
19 Pages

Proteomics Analysis to Assess the Role of Mitochondria in BRCA1-Mediated Breast Tumorigenesis

  • Antonio Concolino,
  • Erika Olivo,
  • Laura Tammè,
  • Claudia Vincenza Fiumara,
  • Maria Teresa De Angelis,
  • Barbara Quaresima,
  • Valter Agosti,
  • Francesco Saverio Costanzo,
  • Giovanni Cuda and
  • Domenica Scumaci

Mitochondria are the organelles deputed to energy production, but they are also involved in carcinogenesis, cancer progression, and metastasis, playing a role in altered energy metabolism in cancer cells. Mitochondrial metabolism is connected with se...

  • Article
  • Open Access
7 Citations
5,962 Views
14 Pages

Association of Proteomics Changes with Al-Sensitive Root Zones in Switchgrass

  • Mahesh Rangu,
  • Zhujia Ye,
  • Sarabjit Bhatti,
  • Suping Zhou,
  • Yong Yang,
  • Tara Fish and
  • Theodore W. Thannhauser

In this paper, we report on aluminum (Al)-induced root proteomic changes in switchgrass. After growth in a hydroponic culture system supplemented with 400 μM of Al, plants began to show signs of physiological stress such as a reduction in photosynthe...

  • Feature Paper
  • Article
  • Open Access
18 Citations
7,115 Views
23 Pages

The Secretome and N-Glycosylation Profiles of the Charophycean Green Alga, Penium margaritaceum, Resemble Those of Embryophytes

  • Eliel Ruiz-May,
  • Iben Sørensen,
  • Zhangjun Fei,
  • Sheng Zhang,
  • David S. Domozych and
  • Jocelyn K. C. Rose

The secretome can be defined as the population of proteins that are secreted into the extracellular environment. Many proteins that are secreted by eukaryotes are N-glycosylated. However, there are striking differences in the diversity and conservati...

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Proteomes - ISSN 2227-7382