Toxics, Volume 13, Issue 9

Heavy metal (HM) contamination of soil is a worldwide problem with adverse consequences for the environment and human health. Microorganisms, as the most active fraction in soil, play a pivotal role in assessing changes in soil quality and maintainin...

Cadmium and arsenic co-contamination found in mining actions indicates major effluence in adjacent farmland soils, disturbing the plant physiology and soil’s microbial community. Phosphorus (P) plays a vital role in reducing soil contamination...

We explored the mass concentrations of water-soluble ions in PM_2.5 and their variations across different time scales and concentration levels. Using the Positive Matrix Factorization (PMF) model and backward trajectory analysis, we focused on identif...

Urban industrialization is a major driver of water pollution, particularly through emerging contaminants that pose significant health risks for humans and ecosystems. This critical review focuses on Bangladesh’s Buriganga and Dhaleshwari rivers...

Microplastic and nanoplastic (MNP) particles have been observed in various human organs. However, polypropylene (PP), one of the top three most commonly detected types of MNPs in terms of quantity, is also present in injections given for the infusion...

Hearing loss (HL) causes numerous challenges for individuals. N,N-diethyl-meta-toluamide (DEET) is a common ingredient in insect repellants and some sunscreens. M-(diethylcarbamoyl) benzoic acid (DCBA) is a DEET metabolite measured in the urine of Na...

The widespread occurrence of nano-plastics (NPs) in aquatic environments poses emerging challenges to the pollutant removal performance and ecological stability of constructed wetlands (CWs). This study investigates the performance of calcium-modifie...

Thyroid hormone (TH) system disruption by chemicals poses a significant concern due to the key role the TH system plays in essential body functions, including the metabolism, growth, and brain development. Animal-based testing methods are resource-de...

Phytoplankton serves as the primary producer in estuarine ecosystems, with its community structure and dynamics being directly influenced by the concentration and ratio of nitrogen (N) and phosphorus (P) nutrients. This study utilized raw water from...

Background: Despite the identification of various environmental factors that increase the risk of multiple sclerosis (MS), the effects of many factors on the etiology of MS remain to be elucidated. In this study, we aimed to investigate the effects o...

The incomplete degradation of degradable plastics may pose potential ecological risks, as it can generate degradable microplastics (DMPs), especially when these DMPs coexist with heavy metals in soil. Taking petrochemical-based poly(butylene adipate-...

Northern Thailand experiences seasonal surges in PM₂.₅ pollution, posing significant respiratory health risks. This cross-sectional study aimed to evaluate associations between PAHs exposure and early health biomarkers. In April 2024, 127 rural resid...

Organophosphorus flame retardants (OPFRs) are emerging alternatives to halogenated compounds, yet their environmental toxicity remains underexplored. This study evaluated the developmental toxicity of two aryl-OPFRs, triphenyl phosphate (TPP) and tri...

Organochlorine insecticides (DDTs), organophosphate insecticides (malathion), carbamate insecticides (carbaryl and thiram), pyrethroid (cypermethrin and fenvalarate) insecticides, and herbicides (glyphosate and atrazine) were selected for this study...

Colorectal cancer (CRC) has a complex etiology involving genetic, lifestyle, and environmental factors. This study investigates the association between exposure to water contaminants and the risk of developing CRC in Lebanon. Population Attributable...

With the transformation of industrial enterprises in China, the relocation of numerous factories has led to the emergence of retired industrial parks with serious pollution. This study investigated the contamination of benzene-based pollutants (BBPs)...

In silico forensic toxicology refers to the emerging application of computational models based on Quantitative Structure–Activity Relationships (QSARs), molecular docking, and predictions regarding Absorption, Distribution, Metabolism, Excretion, and...

Prenatal tobacco smoke exposure (TSE) has been associated with significant alterations in DNA methylation (DNAm), an epigenetic mechanism with potential functional consequences to child development. This pilot study aimed to investigate differential...

The deposition of particulate matter (PM) in the lungs is a health problem that primarily affects individuals working in mines and other highly polluted environments. People living in large cities also accumulate PM in their lungs throughout their li...

Notably, the widespread ubiquity of arsenic and graphene oxide in the environment validates the occurrence of their co-exposure, posing significant threats to target organisms, including humans. Herein, prepuberty, puberty, and maturity were investig...

The impact of mercury (Hg) on biological systems is well documented; however, the long-term effects of low-level exposure in children remain unclear, particularly with respect to oxidative stress and cognitive outcomes. This study evaluated Hg exposu...

This study’s objective was to evaluate genotoxic effects on automotive paint workers who are exposed to a complex mixture of VOCs, heavy metals, and solvents. Biological samples, including blood, urine, and buccal epithelial cells, were collect...

Ametryn (AMT) and clomazone (CLZ) are commonly used herbicides frequently detected in food and water, raising concerns about potential health risks. This study investigated whether AMT and CLZ impair mitochondrial bioenergetics, a key mechanism linke...

Heavy metal contamination in rivers is a serious environmental and public health concern, especially in areas affected by mining. This study evaluated the levels of contamination and the associated ecological and carcinogenic risks in the sediments o...

The emergence of microplastics (MPs) in drinking water supply systems has become a significant environmental challenge. Although the potential impacts of MPs in drinking water on human health remain incompletely understood, the ingestion of MPs throu...

Microplastics have become a global environmental issue, and this challenge has also emerged in river environments. In this study, the Three Gorges Reservoir (TGR) was selected as the research area, and microplastics in water and sediments were chosen...

Degradation is a key natural attenuation mechanism governing the fate of PPCPs during anaerobic digestion (AD) and subsequent soil exposure. Nevertheless, the combined impact of this sequential treatment (AD followed by land application) remains poor...

Objectives: This study planned to determine the biological effects associated with ZnFe₂O₄-NPs exposure using Drosophila melanogaster as an in vivo model. Methods: ZnFe₂O₄-NPs were hydrothermally synthesized, and the development of offspring flies we...

Global production of fisheries and aquaculture products continues to increase, with the fisheries sector increasingly considered essential for global food security and nutrition. As public demand for seafood increases, implementation of safety manage...

Certain metal powders used in the synthesis and processing of high-entropy alloys (HEAs) pose significant health hazards, as many of these metals are toxic substances with no biological role in the human body. These metals can mimic essential element...

Background: Abiogenesis is hypothesized to have occurred in the aquatic environments of the early Earth approximately 3.8–4.0 billion years ago, in oceans containing high concentrations of ions (Na⁺ ≈ 470 mmol/L, Cl⁻ ≈ 545 mmo...

Although asbestos use has been banned in many countries, including South Korea, the long latency period of asbestos-related diseases remains a serious public health concern. We conducted a nationwide, registry-based retrospective study to estimate th...

Chromium (VI) mobility in soils critically influenced groundwater contamination risks, but accurate predictions were hindered by the lack of systematic retardation factor (R) data across China’s diverse soils. This study combined Bromide anion...

BPAF (Bisphenol AF), one of the primary substitutes for BPA (Bisphenol A), is widely used in the production of plastics, optical fibers, and other materials. During the use of these products, BPAF inevitably enters the environment and exerts toxic ef...

Bisphenol A (BPA) replacement chemicals are used in products like food packaging, plastic piping, and sportswear. While they can be toxic, their neurotoxicity is less understood. The aim of this study was to treat differentiated human SH-SY5Y cells w...

Tartrazine (TZ, also known as FD&C Yellow No. 5 or E102) is a synthetic, water-soluble yellow food dye widely used in the food and pharmaceutical industries. Some studies have associated TZ with allergic reactions, especially among people with dy...

Mono(2-ethylhexyl) phthalate (MEHP), a bioactive metabolite of di(2-ethylhexyl) phthalate (DEHP), has been detected in the placenta and urine of pregnant women and is linked to adverse pregnancy outcomes. However, its effects on mitochondrial homeost...

Freshwater pollution is a global issue that can impact aquatic organisms in multiple ways. One of the many detrimental consequences of freshwater pollution is the disruption of the intestinal microbiome in aquatic animals. This review addresses the i...

Arsenic-containing wastewater and soil systems are a serious hazard to public health and the environment, particularly in areas where agriculture and drinking water depend on groundwater. Therefore, the removal of arsenic contamination from soil, wat...

Chemotherapy-induced peripheral neuropathy remains a significant side effect of cancer treatment, often requiring dose reductions or even discontinuation of therapy. Paclitaxel (PTX), a widely used chemotherapeutic agent for solid tumors, is particul...

Soman, an organophosphorus nerve agent, induces neurotoxicity primarily by inhibiting acetylcholinesterase, triggering a series of pathological events including cholinergic crisis, seizures, calcium overload, oxidative stress, mitochondrial dysfuncti...

Pesticide usage in the integrated rice–crayfish system has aroused lots of attention all over the world. Especially in China, fish farmers often use copper sulfate and pendimethalin to remove moss from aquaculture water and glyphosate to remove weeds...

Levonorgestrel (LNG), a synthetic progestin widely used in pharmaceuticals, is increasingly recognized as an emerging aquatic contaminant capable of exerting adverse biological effects beyond endocrine disruption. Acting in a xenobiotic-like manner,...

This study evaluated the reproductive toxicity and reversibility of gossypol exposure in female Institute of Cancer Research (ICR) mice using the Targeted Risk Assessment of Environmental Chemicals (TRAEC) framework. Mice treated with gossypol (20 mg...

As the terminal reservoir of the South-to-North Water Diversion’s Eastern Route, Dongping Lake is critical for safeguarding the northern water supply. Analysis of 33 water–sediment sites revealed the following. (1) Waterborne heavy metals (HMs) below...

Chronic kidney disease of unknown origin (CKDu) is a public health concern, particularly in agricultural communities, with multiple environmental exposures hypothesized as potential contributors. This study employed a targeted exposure assessment usi...

One of the key tasks in the geological disposal of radioactive waste is to investigate the blocking ability of different host rocks on nuclide migration in the disposal site. This study conducted experimental and numerical methods to the adsorption,...

This study developed a novel adsorbent for Cr (VI) removal from wastewater by grafting N-[(dimethylamino)methylene]thiourea (TUFA) onto lignin. The resulting TUFA-functionalized lignin adsorbent AL was comprehensively characterized using scanning ele...

The potential benefits of nanopesticide use over standard pesticides include more precise application at reduced application rates, lower premature degradation, and decreased direct impacts to target organisms. However, field scale investigations of...

Background: Heated tobacco products (HTPs) are marketed as reduced-harm alternatives to conventional cigarettes (CCs) and are increasingly used by young adults and occasional smokers. However, their acute nicotine delivery and user experience remain...