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Article
Peer-Review Record

Biomechanical Evaluation of Hydroxyapatite/poly-l-lactide Fixation in Mandibular Body Reconstruction with Fibula Free Flap: A Finite Element Analysis Incorporating Material Properties and Masticatory Function Evaluation

Bioengineering 2024, 11(10), 1009; https://doi.org/10.3390/bioengineering11101009
by Sang-Min Lee 1,†, Tae-Gon Jung 2,†, Won-Hyeon Kim 3,4, Bongju Kim 4,* and Jee-Ho Lee 1,*
Reviewer 1:
Reviewer 2: Anonymous
Bioengineering 2024, 11(10), 1009; https://doi.org/10.3390/bioengineering11101009
Submission received: 19 September 2024 / Revised: 1 October 2024 / Accepted: 9 October 2024 / Published: 11 October 2024

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors 1. For Table 1, please list references for each component. 2. Line 143, please clarify in more detail why cancellous bone was not a significant factor. 3. Is there mesh sensitivity analysis conducted to verify that results based on Table 2 are convergent? 4. Are there any experimental measurements available to verify the simulation? 5. Please expand the discussion on the contrast identified on line 295.

Author Response

Please see attached file.

Author Response File: Author Response.docx

Reviewer 2 Report

Comments and Suggestions for Authors

The authors described "Biomechanical evaluation of hydroxyapatite/poly-l-lactide fixation in mandibular body reconstruction with fibula free flap: A finite element analysis incorporating material properties and masticatory function evaluation" through finite element analysis (FEA). The biomechanical integrity of Ti and HA-PLLA fixation systems used in reconstruction surgery with fibula flap was compared using FEA simulation. This study should be informative and attractive for potential readers. I have some question and suggestions to improve this manuscript.

1. Why did you choose HA-PLLA among biodegradable materials? As there are a lot of biodegradable materials in the world, they should add the reason in Introduction or Discussion.

2. How does this HA-PLLA compare with the One-plate fixation? The fibula is often thin, forcing fixation with a single large plate (Yamakawa S, et al. BMC surgery 2021). Please add the content of the one-plate fixation method with fibula flap in Discussion.

Author Response

Please see attached file.

Author Response File: Author Response.docx

Round 2

Reviewer 2 Report

Comments and Suggestions for Authors

The authors revised the manuscript precisely. Thank you for this opportunity.

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