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Geriatrics, Volume 10, Issue 2

2025 April - 28 articles

Cover Story: Research on frailty as a predictor of adverse health outcomes in psychiatric patients is relatively limited, and its function as a predictor of adverse drug reactions in older psychiatric patients has not been studied at all. In a prospective cohort study including 77 older psychiatric in- and outpatients with a mean age of 74 years, treated in one large psychiatric institute in the Netherlands, frailty was assessed at baseline using different operationalizations of the Fried frailty criteria. We found that frail patients were 40% more likely to discontinue psychotropic treatment compared to non-frail patients (OR = 1.4; 95% CI 0.6–3.7, p = 0.468) and they had a 60% higher chance of experiencing adverse drug reactions (OR = 1.6, 95% CI 0.6–4.1, p = 0.345); however, these differences were not statistically significant. A lack of power could explain our negative results. View this paper
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Articles (28)

  • Article
  • Open Access
973 Views
20 Pages

An Optimal Beneficiary Profile to Ensure Focused Interventions for Older Adults

  • Dorina-Claudia Bălan,
  • Rozeta Drăghici,
  • Ioana Găiculescu,
  • Alexandra Rusu,
  • Andrada-Elena Stan and
  • Polixenia Stan

Background: Aging is a lifelong process, and many chronic diseases and geriatric syndromes are influenced by lifestyle factors. For active aging and maintaining functional capacity facilitate health, there are essential aspects in geriatric care. Our...

  • Article
  • Open Access
1,513 Views
18 Pages

Culturally Tailored Community Brain Health Education for Chinese Americans Aged 50 or Above: A Mixed-Methods Open Pilot Study

  • Kaipeng Wang,
  • Fei Sun,
  • Peiyuan Zhang,
  • Carson M. De Fries,
  • Xiaoyouxiang Li,
  • Jie Zhu and
  • My Ngoc To

Background: Chinese Americans, the largest Asian American subgroup in the U.S., face linguistic, cultural, and socio-economic barriers to dementia prevention. To promote brain health in this population, a culturally tailored community approach is ess...

  • Article
  • Open Access
1 Citations
941 Views
11 Pages

Aim/Objectives: To investigate whether frailty predicts adherence to psychotropic drug treatment or adverse drug reactions, within 6 months after treatment initiation. Methods: A prospective cohort study including 77 patients over the age of 65, trea...

  • Article
  • Open Access
1 Citations
1,414 Views
16 Pages

Impact of Rehabilitation Intervention for Cancer Patients with Spinal Bone Metastasis: Psychosocial and Clinical Outcomes

  • Noémi Németh,
  • Lavinia Davidescu,
  • Liviu Lazăr,
  • Florica Voiță-Mekeres,
  • Mariana Racoviță and
  • Călin Tudor Hozan

Background/Objectives: Cancer remains a significant global health issue in the 21st century, accounting for 16.8% of all deaths and 22.8% of noncommunicable disease (NCD) deaths globally. This study investigated the impact of a novel integrated rehab...

  • Article
  • Open Access
4,527 Views
25 Pages

Development of an Adult Daycare Center Service Model for the Elderly Through Community Participation: An Action Research Approach

  • Benjayamas Pilayon,
  • Kanin Chueaduangpui,
  • Juthaluck Saentho,
  • Ruchakron Kongmant and
  • Niruwan Turnbull

Introduction: This study aimed to develop a service model for daycare centers for the elderly through community participation using participatory action research methods. The objectives were threefold: (1) to investigate the current situation of the...

  • Article
  • Open Access
1,173 Views
14 Pages

Factors Associated with Mortality and Short-Term Patient Outcomes for Hip Fracture Repair in the Elderly Based on Preoperative Anticoagulation Status

  • Vimal Desai,
  • Priscilla H. Chan,
  • Kathryn E. Royse,
  • Ronald A. Navarro,
  • Glenn R. Diekmann,
  • Kent T. Yamaguchi,
  • Elizabeth W. Paxton and
  • Chunyuan Qiu

Background: The one-year mortality risk for elderly patients undergoing proximal femur fracture repair surgery is three to four times higher compared to the general population. Other than time to surgery, risk factors for postoperative morbidity and...

  • Review
  • Open Access
1 Citations
2,703 Views
15 Pages

Background/Objectives: Dysphagia, a prevalent condition among older adults, poses significant health risks if not accurately assessed and managed. Instrumental assessments (IAs) like videofluoroscopic swallowing study (VFSS) and fiberoptic endoscopic...

  • Article
  • Open Access
4 Citations
2,522 Views
16 Pages

The Role of Inflammatory Sarcopenia in Increasing Fall Risk in Older Adults: Exploring the Impact on Mobility-Impaired and Immunocompromised Patients

  • Marc-Dan Blajovan,
  • Simona-Alina Abu-Awwad,
  • Mirela-Cleopatra Tomescu,
  • Cristina Tudoran,
  • Daniela Gurgus,
  • Anca Dinu and
  • Ahmed Abu-Awwad

Background/Objectives: Inflammatory sarcopenia, characterized by muscle weakness exacerbated by chronic systemic inflammation, has emerged as a critical factor in fall risk among older adults. While previous studies have examined sarcopenia and infla...

  • Article
  • Open Access
1 Citations
1,449 Views
16 Pages

Implications of Intra-Individual Variability in Motor Performance on Functional Mobility in Stroke Survivors

  • Neha Lodha,
  • Prakruti Patel,
  • Evangelos A. Christou,
  • Anjali Tiwari and
  • Manfred Diehl

Background: Motor impairments following stroke contribute to deficits in functional mobility. Traditionally, these impairments are quantified by mean-level motor performance. However, this mean-level approach neglects the well-established fact that m...

  • Review
  • Open Access
4 Citations
3,370 Views
11 Pages

Rhinitis in the Geriatric Population: Epidemiological and Cytological Aspects

  • Matteo Gelardi,
  • Rossana Giancaspro,
  • Elisa Boni,
  • Mario Di Gioacchino,
  • Giulia Cintoli,
  • Michele Cassano and
  • Maria Teresa Ventura

Allergic rhinitis (AR), traditionally considered as a childhood condition, is increasingly recognized among older adults, driven by rising life expectancy and environmental factors. Although allergic sensitization declines with age, AR prevalence in...

  • Article
  • Open Access
1,341 Views
13 Pages

Background/Objectives: Posture is a significant indicator of health status in older adults. This study aimed to develop an automatic posture assessment tool based on sagittal photographs by validating recognition models using convolutional neural net...

  • Review
  • Open Access
7 Citations
8,548 Views
17 Pages

Comprehensive Geriatric Health Assessment Core Competencies and Skills for Primary Care Nurses: A Scoping Review

  • Ioanna Dimitriadou,
  • Eloranta Sini,
  • Jekaterina Šteinmiller,
  • Maria Saridi,
  • Anna Lundberg,
  • Magdalena Häger,
  • Ingibjorg Hjaltadottir,
  • Sigrun S. Skuladottir,
  • Nina Korsström and
  • Evangelos C. Fradelos
  • + 2 authors

Objective: This scoping review aims to explore and synthesize the core competencies and skills required for primary care nurses conducting comprehensive geriatric assessments. Comprehensive geriatric assessments have become integral to providing holi...

  • Article
  • Open Access
2 Citations
1,695 Views
9 Pages

Establishment of a Mandarin Chinese Version of the Oral Frailty Index-8 and Exploration of the Association Between Oral Frailty and Sarcopenia

  • Chen-Cheng Yang,
  • Hsiang-Tai Chen,
  • Katsuya Iijima,
  • Tomoki Tanaka,
  • Chia-Yen Dai,
  • Sang-Ju Yu and
  • Hung-Yi Chuang

Objective: The aim of our study was to introduce a Mandarin Chinese version of the oral frailty assessment and explore the relationship between oral frailty and sarcopenia. A total of 409 elders (171 male, 238 female) participated in surveys using th...

  • Article
  • Open Access
1,374 Views
12 Pages

Background/Objectives: In older patients, falls constitute a significant public health concern and a major cause of hospital admission. Fall-risk-increasing drugs (FRIDs) represent a key risk factor for falls. Therefore, modifying these drugs represe...

  • Article
  • Open Access
1,736 Views
25 Pages

Aging-Related Changes in Bimanual Coordination as a Screening Tool for Healthy Aging

  • Yusuke Shizuka,
  • Shin Murata,
  • Akio Goda,
  • Shun Sawai,
  • Shoya Fujikawa,
  • Ryosuke Yamamoto,
  • Takayuki Maru,
  • Kotaro Nakagawa and
  • Hideki Nakano

Background/Objectives: The steady increase in the global older adult population highlights critical challenges, including the development of preventive strategies to extend healthy life expectancy and support independence in activities of daily livin...

  • Article
  • Open Access
1,637 Views
13 Pages

Prevalence of Poor Diet Quality and Associated Factors Among Older Adults from the Bagé Cohort Study of Ageing, Brazil (SIGa-Bagé)

  • Tainã Dutra Valério,
  • Rosália Garcia Neves,
  • Elaine Thumé,
  • Karla Pereira Machado and
  • Elaine Tomasi

(1) Background: The accelerated aging of the population raises concerns about the diet of older adults due to its relationship with health and quality of life. This study aimed to investigate the prevalence of poor diet quality and its association wi...

  • Review
  • Open Access
6 Citations
6,338 Views
21 Pages

Anemia in Elderly Patients: Contribution of Renal Aging and Chronic Kidney Disease

  • Simone Santos,
  • Irina Lousa,
  • Márcia Carvalho,
  • Maria Sameiro-Faria,
  • Alice Santos-Silva and
  • Luís Belo

Renal aging is a physiological process characterized by structural and functional changes in the kidneys. The presence of disorders or pathologies can exacerbate these age-related changes, potentially leading to organ dysfunction. Chronic kidney dise...

  • Article
  • Open Access
2,898 Views
14 Pages

Effect of Protein Supplementation on Orthostatic Hypotension in Older Adult Patients with Heart Failure

  • Gohar Azhar,
  • Amanda K. Pangle,
  • Karen Coker,
  • Shakshi Sharma and
  • Jeanne Y. Wei

Purpose: Heart failure (HF) impairs physical performance and increases the incidence of orthostatic hypotension (OH). Individuals with OH have a higher risk of falls, which are a major source of morbidity and mortality in older adults. Dietary protei...

  • Case Report
  • Open Access
1 Citations
2,184 Views
10 Pages

Case Report: Weakness and Recurrent Falls in an Older Patient

  • Mercedes Galloway,
  • Nannette Hoffman,
  • Christopher Lawrence Bray,
  • Ahmed Ebrahim,
  • Brittany Puebla and
  • David Ritchie

Background/Objectives: Lower-extremity weakness in older adults is often overlooked, yet it can have reversible or medical causes that contribute to increased falls. Common factors include vision disturbances, impaired balance due to otolith dysfunct...

  • Article
  • Open Access
1 Citations
2,408 Views
13 Pages

Assessing Frailty in the Older: The Role of Bite Force as an Independent Indicator

  • Luciano Maia Alves Ferreira,
  • José Brito,
  • Josie Resende Torres da Silva,
  • Marcelo Lourenço da Silva,
  • Maia e Maia Fischel e Andrade,
  • André Júdice,
  • José João Mendes,
  • Vanessa Machado,
  • João Thiago Botelho and
  • Simone Cecílio Hallak Regalo

Background: This study investigates the relationship between bite force and grip strength as indicators of frailty in older adults. Frailty syndrome, characterized by increased vulnerability to adverse health outcomes, poses significant challenges in...

  • Article
  • Open Access
4 Citations
3,007 Views
11 Pages

Cognitive Performance Among Older Adults with Subjective Cognitive Decline

  • Ramón López-Higes,
  • Susana Rubio-Valdehita,
  • David López-Sanz,
  • Sara M. Fernandes,
  • Pedro F. S. Rodrigues and
  • María Luisa Delgado-Losada

Objectives: The main objective of this cross-sectional study was to investigate if there are significant differences in cognition between a group of older adults with subjective cognitive decline (SCD) and cognitively intact controls. Methods: An ini...

  • Article
  • Open Access
1,792 Views
10 Pages

Validation of the Italian Version of the Rapid Geriatric Assessment in Community-Dwelling Older Adults

  • Carlotta Tacchino,
  • Luca Carmisciano,
  • Elena Page,
  • Silvia Ottaviani,
  • Luca Tagliafico,
  • Alda Boccini,
  • Alessio Signori,
  • Chiara Giannotti,
  • Alessio Nencioni and
  • Fiammetta Monacelli

Background/Objectives: The Rapid Geriatric Assessment (RGA) is a tool designed to screen for frailty, sarcopenia, anorexia related to aging, and cognitive impairment. This study aimed to translate and validate the RGA for use among Italian community-...

  • Article
  • Open Access
7 Citations
4,165 Views
18 Pages

Aging Gut-Brain Interactions: Pro-Inflammatory Gut Bacteria Are Elevated in Fecal Samples from Individuals Living with Alzheimer’s Dementia

  • Alison I. C. Donaldson,
  • Claire L. Fyfe,
  • Jennifer C. Martin,
  • Ellen E. Smith,
  • Graham W. Horgan,
  • Phyo K. Myint,
  • Alexandra M. Johnstone and
  • Karen P. Scott

Background/Objectives: Alzheimer’s disease (AD) is the most common form of dementia, characterized by an irreversible decline in cognitive function. The pathogenesis of several neurodegenerative disorders has been linked to changes in the gut microbi...

  • Article
  • Open Access
1,694 Views
11 Pages

Background/Objectives: Friends and family members of people who are discharged from hospital after a fracture often take on caring roles, since these patients have reduced independence during recovery. Previous literature suggests that these individu...

  • Article
  • Open Access
1,507 Views
12 Pages

Background: Experiences of dental pain among older people living with dementia, particularly those residing in care homes, have been identified as an under-researched area. There is an urgent need for initiatives, co-developed with experts according...

  • Article
  • Open Access
2,688 Views
14 Pages

Mitigating Diarrhoea-Related Inflammation in Frail Older Adults with Postbiotic-Enhanced Oral Rehydration Solution: Insights from a Randomised, Double-Blind, Placebo-Controlled Study

  • Julian Andrés Mateus Rodríguez,
  • Patricia Rodríguez Sanz,
  • Edgar Kostandyan,
  • Rubén Palacios Sanchez,
  • María Luz Pino Roque,
  • Patricia Chaves Vasquez and
  • Pedro Roy Millán

Background/Objectives: Diarrhoea in older adults can lead to dehydration and malnutrition, impaired gut barrier function, and reduced quality of life. Unresolved inflammation during diarrhoea episodes contributes to relapse and complications. This ra...

  • Article
  • Open Access
3 Citations
1,706 Views
11 Pages

Impact of SARS-CoV-2 Infection on Erythropoietin Resistance Index in Hemodialysis Patients

  • Guido Gembillo,
  • Luca Soraci,
  • Luigi Peritore,
  • Rossella Siligato,
  • Vincenzo Labbozzetta,
  • Alfio Edoardo Giuffrida,
  • Felicia Cuzzola,
  • Claudia Spinella,
  • Adolfo Romeo and
  • Domenico Santoro
  • + 3 authors

24 February 2025

Background/Objectives: Hemodialysis (HD) patients with advanced chronic kidney disease (CKD) are highly vulnerable to complications from SARS-CoV-2 infection. Anemia management in this population is complex, particularly due to erythropoietin resista...

  • Review
  • Open Access
1 Citations
8,436 Views
22 Pages

Choline Alphoscerate: A Therapeutic Option for the Management of Subthreshold Depression in the Older Population

  • Nicolò Granata,
  • Marco Vercesi,
  • Annamaria Bonfanti,
  • Claudio Mencacci,
  • Ilaria Coco,
  • Mario Mangrella,
  • Roberto Piazza and
  • Giancarlo Cerveri

20 February 2025

Background and Objectives: Subthreshold depression (StD) presents with depressive symptoms similar to major depressive disorder (MDD) but of lower intensity. Despite its milder form, StD is significantly prevalent in the older population, affecting u...

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Geriatrics - ISSN 2308-3417