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Journal of Fungi, Volume 7, Issue 2

February 2021 - 92 articles

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Cover Story: This review explains in a simplified way the information published in recent years on the immune response to the emerging fungi Scedosporium/Lomentospora. Fungal cell wall components, including peptidorhamnomannans, α-glucans and glucosylceramides, are involved in immune response activation following their recognition by TLR2, TLR4 and Dectin-1. After that, cytokine synthesis and antifungal activity of different phagocytes and epithelial cells against these fungi are species-specific. Furthermore, to evade host immune response, these fungi use different evasion mechanisms, including inducing host non-protective response, masking fungal molecular patterns and destructing host defense proteins. However, many aspects remain to be elucidated, and more research is necessary to shed light on the immune response to these fungi. View this paper

Articles (92)

  • Review
  • Open Access
38 Citations
4,122 Views
13 Pages

23 February 2021

Studies describing invasive fungal infections (IFIs) after chimeric antigen receptor-modified T-cell (CAR-T-cell) therapy are limited. Although post-CAR-T-cell IFIs appear to be uncommon, they are associated with significant morbidity and mortality....

  • Review
  • Open Access
17 Citations
4,099 Views
26 Pages

Paracoccidioidomycosis Diagnosed in Europe—A Systematic Literature Review

  • Gernot Wagner,
  • Deddo Moertl,
  • Anna Glechner,
  • Verena Mayr,
  • Irma Klerings,
  • Casey Zachariah,
  • Miriam Van den Nest,
  • Gerald Gartlehner and
  • Birgit Willinger

23 February 2021

Paracoccidioidomycosis is a systemic mycosis that is endemic in geographical regions of Central and South America. Cases that occur in nonendemic regions of the world are imported through migration and travel. Due to the limited number of cases in Eu...

  • Article
  • Open Access
14 Citations
3,841 Views
23 Pages

Development of Nano-Antifungal Therapy for Systemic and Endemic Mycoses

  • Jorge H. Martínez-Montelongo,
  • Iliana E. Medina-Ramírez,
  • Yolanda Romo-Lozano,
  • Antonio González-Gutiérrez and
  • Jorge E. Macías-Díaz

23 February 2021

Fungal mycoses have become an important health and environmental concern due to the numerous deleterious side effects on the well-being of plants and humans. Antifungal therapy is limited, expensive, and unspecific (causes toxic effects), thus, more...

  • Article
  • Open Access
7 Citations
3,447 Views
15 Pages

Preliminary Examination of the Toxicity of Spalting Fungal Pigments: A Comparison between Extraction Methods

  • Badria H. Almurshidi,
  • R.C. Van Court,
  • Sarath M. Vega Gutierrez,
  • Stacey Harper,
  • Bryan Harper and
  • Seri C. Robinson

22 February 2021

Spalting fungal pigments have shown potential in technologies ranging from green energy generation to natural colorants. However, their unknown toxicity has been a barrier to industrial adoption. In order to gain an understanding of the safety of the...

  • Article
  • Open Access
25 Citations
4,853 Views
7 Pages

Comparison of Two Commercially Available qPCR Kits for the Detection of Candida auris

  • Janko Sattler,
  • Janina Noster,
  • Anne Brunke,
  • Georg Plum,
  • Pia Wiegel,
  • Oliver Kurzai,
  • Jacques F. Meis and
  • Axel Hamprecht

22 February 2021

Candida auris is an emerging pathogen with resistance to many commonly used antifungal agents. Infections with C. auris require rapid and reliable detection methods to initiate successful medical treatment and contain hospital outbreaks. Conventional...

  • Article
  • Open Access
29 Citations
3,832 Views
17 Pages

The Emericellipsins A–E from an Alkalophilic Fungus Emericellopsis alkalina Show Potent Activity against Multidrug-Resistant Pathogenic Fungi

  • Anastasia E. Kuvarina,
  • Irina A. Gavryushina,
  • Alexander B. Kulko,
  • Igor A. Ivanov,
  • Eugene A. Rogozhin,
  • Marina L. Georgieva and
  • Vera S. Sadykova

21 February 2021

Novel antimicrobial peptides with antifungal and cytotoxic activity were derived from the alkalophilic fungus Emericellopsis alkalina VKPM F1428. We previously reported that this strain produced emericellipsin A (EmiA), which has strong antifungal an...

  • Review
  • Open Access
43 Citations
6,568 Views
14 Pages

Endemic and Other Dimorphic Mycoses in The Americas

  • Shawn R. Lockhart,
  • Mitsuru Toda,
  • Kaitlin Benedict,
  • Diego H. Caceres and
  • Anastasia P. Litvintseva

20 February 2021

Endemic fungi are thermally dimorphic fungi that have a limited geographic range and can cause both primary disease and opportunistic infections. The Americas are home to more genera of endemic fungi than anywhere else on earth. These include Coccidi...

  • Review
  • Open Access
13 Citations
4,389 Views
19 Pages

Molecular Epidemiology of Aspergillus fumigatus in Chronic Pulmonary Aspergillosis Patients

  • Mireille H. van der Torre,
  • Hongwei Shen,
  • Riina Rautemaa-Richardson,
  • Malcolm D. Richardson and
  • Lilyann Novak-Frazer

20 February 2021

Molecular fungal genotyping techniques developed and employed for epidemiological studies have understandably concentrated on establishing the genetic diversity of Aspergillus fumigatus in invasive aspergillosis due to its severity, the urgency for t...

  • Article
  • Open Access
10 Citations
3,223 Views
11 Pages

Transcriptome Profiles of Sporisorium reilianum during the Early Infection of Resistant and Susceptible Maize Isogenic Lines

  • Boqi Zhang,
  • Nan Zhang,
  • Qianqian Zhang,
  • Qianya Xu,
  • Tao Zhong,
  • Kaiyue Zhang and
  • Mingliang Xu

19 February 2021

The biotrophic fungus Sporisorium reilianum causes destructive head smut disease in maize (Zea mays L.). To explore the pathogenicity arsenal of this fungus, we tracked its transcriptome changes during infection of the maize seedling mesocotyls of tw...

  • Article
  • Open Access
33 Citations
4,413 Views
29 Pages

18 February 2021

Lolium perenne infected with the fungal endophyte Epichloë festucae var. lolii have specific, endophyte strain-dependent, chemical phenotypes in their above-ground tissues. Differences in these chemical phenotypes have been largely associated with cl...

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J. Fungi - ISSN 2309-608XCreative Common CC BY license