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Gels, Volume 9, Issue 5

2023 May - 80 articles

Cover Story: The general theory is developed for the transient electrophoresis of a colloidal particle in a polymer gel medium. The Laplace transform of the particle electrophoretic mobility with respect to time is derived by considering the long-range hydrodynamic interaction between the particle and the polymer gel medium. According to the obtained Laplace transform, the transient gel electrophoretic mobility approaches the steady gel electrophoretic mobility as time approaches infinity. The present theory covers the transient free-solution electrophoresis. It is shown that the relaxation time for the transient gel mobility to reach its steady value is shorter than that of the transient free-solution mobility and becomes shorter as the Brinkman screening length decreases. View this paper
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Articles (80)

  • Review
  • Open Access
59 Citations
11,103 Views
39 Pages

Application of Silk-Fibroin-Based Hydrogels in Tissue Engineering

  • Yihan Lyu,
  • Yusheng Liu,
  • Houzhe He and
  • Hongmei Wang

22 May 2023

Silk fibroin (SF) is an excellent protein-based biomaterial produced by the degumming and purification of silk from cocoons of the Bombyx mori through alkali or enzymatic treatments. SF exhibits excellent biological properties, such as mechanical pro...

  • Review
  • Open Access
69 Citations
9,308 Views
29 Pages

22 May 2023

Alginates are polysaccharides that are produced naturally and can be isolated from brown sea algae and bacteria. Sodium alginate (SA) is utilized extensively in the field of biological soft tissue repair and regeneration owing to its low cost, high b...

  • Article
  • Open Access
10 Citations
3,798 Views
12 Pages

21 May 2023

Objectives: Impression materials could be a source of cross-contamination due to the presence of microorganisms from blood and saliva inside the oral cavity. Nevertheless, routinely performed post-setting disinfection could compromise the dimensional...

  • Article
  • Open Access
15 Citations
4,107 Views
17 Pages

Polyurethane Shape Memory Polymer/pH-Responsive Hydrogel Hybrid for Bi-Function Synergistic Actuations

  • Shuyi Peng,
  • Xingyu Cao,
  • Ye Sun,
  • Lin Chen,
  • Chao Ma,
  • Lang Yang,
  • Hongliang Zhao,
  • Qijie Liu,
  • Zhenzhong Liu and
  • Chunxin Ma

21 May 2023

Stimuli-responsive actuating hydrogels response to the external stimulus with complex deformation behaviors based on the programmable anisotropic structure design are one of the most important smart soft materials, which have great potential applicat...

  • Article
  • Open Access
11 Citations
2,657 Views
12 Pages

Experimental Study on Enhanced Oil Recovery of PPG/ASP Heterogeneous System after Polymer Flooding

  • Yanfu Pi,
  • Zailai Su,
  • Ruibo Cao,
  • Bo Li,
  • Jinxin Liu,
  • Xinyu Fan and
  • Mingjia Zhao

19 May 2023

Following the application of polymer flooding in Daqing Oilfield, the heterogeneity between different layers has intensified, resulting in the formation of more favorable seepage channels and cross-flow of displacement fluids. Consequently, the circu...

  • Article
  • Open Access
8 Citations
2,755 Views
14 Pages

19 May 2023

Gamma radiation technique for the preparation of pure hydrogels is gaining popularity worldwide. Superabsorbent hydrogels play vital roles in different fields of application. The present work mainly focuses on the preparation and characterization of...

  • Article
  • Open Access
7 Citations
3,075 Views
19 Pages

Microbial Polysaccharide-Based Formulation with Silica Nanoparticles; A New Hydrogel Nanocomposite for 3D Printing

  • Maria Minodora Marin,
  • Ioana Catalina Gifu,
  • Gratiela Gradisteanu Pircalabioru,
  • Madalina Albu Kaya,
  • Rodica Roxana Constantinescu,
  • Rebeca Leu Alexa,
  • Bogdan Trica,
  • Elvira Alexandrescu,
  • Cristina Lavinia Nistor and
  • Raluca Ianchis
  • + 1 author

19 May 2023

Natural polysaccharides are highly attractive biopolymers recommended for medical applications due to their low cytotoxicity and hydrophilicity. Polysaccharides and their derivatives are also suitable for additive manufacturing, a process in which va...

  • Review
  • Open Access
8 Citations
4,053 Views
21 Pages

Coinage Metals Doped ZnO Obtained by Sol-Gel Method—A Brief Review

  • Cristina Maria Vlăduț,
  • Oana-Cătălina Mocioiu and
  • Elena Mirabela Soare

18 May 2023

ZnO is one of the most studied oxides due to its nontoxic nature and remarkable properties. It has antibacterial and UV-protection properties, high thermal conductivity, and high refractive index. Various ways have been used to synthesize and fabrica...

  • Review
  • Open Access
44 Citations
7,682 Views
22 Pages

Progress in Surface Modification of Titanium Implants by Hydrogel Coatings

  • Huangqin Chen,
  • Rui Feng,
  • Tian Xia,
  • Zhehan Wen,
  • Qing Li,
  • Xin Qiu,
  • Bin Huang and
  • Yuesheng Li

18 May 2023

Although titanium and titanium alloys have become the preferred materials for various medical implants, surface modification technology still needs to be strengthened in order to adapt to the complex physiological environment of the human body. Compa...

  • Article
  • Open Access
5 Citations
3,123 Views
23 Pages

Theoretical and Experimental Aspects of Sodium Diclofenac Salt Release from Chitosan-Based Hydrogels and Possible Applications

  • Loredana Maria Himiniuc,
  • Razvan Socolov,
  • Irina Nica,
  • Maricel Agop,
  • Constantin Volovat,
  • Lacramioara Ochiuz,
  • Decebal Vasincu,
  • Ana Maria Rotundu,
  • Iulian Alin Rosu and
  • Simona Ruxandra Volovat
  • + 1 author

17 May 2023

Two formulations based on diclofenac sodium salt encapsulated into a chitosan hydrogel were designed and prepared, and their drug release was investigated by combining in vitro results with mathematical modeling. To understand how the pattern of drug...

  • Review
  • Open Access
11 Citations
2,940 Views
32 Pages

17 May 2023

Hydrogels have many useful physicochemical properties which, in combination with their biocompatibility, suggest their application as a drug delivery system for the local and prorogated release of drugs. However, their drug-absorption capacity is lim...

  • Article
  • Open Access
12 Citations
3,318 Views
15 Pages

Gel Properties and Structural Characteristics of Composite Gels of Soy Protein Isolate and Silver Carp Protein

  • Li Zheng,
  • Joe M. Regenstein,
  • Linyi Zhou,
  • Sayed Mohamed Mokhtar and
  • Zhongjiang Wang

17 May 2023

Problems with silver carp protein (SCP) include a strong fishy odor, low gel strength of SCP surimi, and susceptibility to gel degradation. The objective of this study was to improve the gel quality of SCP. The effects of the addition of native soy p...

  • Article
  • Open Access
5 Citations
2,838 Views
13 Pages

Graphene Oxide/Styrene-Butadiene Latex Hybrid Aerogel with Improved Mechanical Properties by PEI Grafted GO and CNT

  • Zetian Zhao,
  • Lina Zhang,
  • Yinghu Song,
  • Lichun Ma,
  • Jialiang Li,
  • Min Zhao,
  • Xueliang Ji,
  • Jianfei Gao,
  • Guojun Song and
  • Xiaoru Li

16 May 2023

Graphene oxide aerogel (GOA) has wide application prospects due to its low density and high porosity. However, the poor mechanical properties and unstable structure of GOA have limited its practical applications. In this study, polyethyleneimide (PEI...

  • Review
  • Open Access
57 Citations
7,742 Views
19 Pages

16 May 2023

The enervating side effects of chemotherapeutic drugs have necessitated the use of targeted drug delivery in cancer therapy. To that end, thermoresponsive hydrogels have been employed to improve the accumulation and maintenance of drug release at the...

  • Review
  • Open Access
15 Citations
11,205 Views
38 Pages

Recent Progress in Gels for Neuropathic Pain

  • Ciprian Pușcașu,
  • Anca Zanfirescu and
  • Simona Negreș

16 May 2023

Neuropathic pain is a complex and debilitating condition that affects millions of people worldwide. While several treatment options are available, they often have limited efficacy and are associated with adverse effects. In recent years, gels have em...

  • Review
  • Open Access
52 Citations
6,639 Views
26 Pages

Recent Advances in Nanocellulose Aerogels for Efficient Heavy Metal and Dye Removal

  • Azfaralariff Ahmad,
  • Mohamad Anuar Kamaruddin,
  • Abdul Khalil H.P.S.,
  • Esam Bashir Yahya,
  • Syaifullah Muhammad,
  • Samsul Rizal,
  • Mardiana Idayu Ahmad,
  • Indra Surya and
  • C. K. Abdullah

16 May 2023

Water pollution is a significant environmental issue that has emerged because of industrial and economic growth. Human activities such as industrial, agricultural, and technological practices have increased the levels of pollutants in the environment...

  • Article
  • Open Access
3 Citations
2,828 Views
22 Pages

Alginate Hydrogel Formulation with Ketorolac for the Treatment of Pain Related Sialolithiasis

  • Cristina Silva,
  • Gladys Ramos-Yacasi,
  • Mireia Mallandrich,
  • Helena Colom-Codina,
  • Joaquim Suñer-Carbó,
  • Noelia Pérez-González,
  • Ana Cristina Calpena and
  • Francisco Fernández-Campos

16 May 2023

Sialolithiasis mainly affects the oral salivary glands due to the presence of small stones that obstruct the secretion of saliva. The treatment and control of pain and inflammation during the course of this pathology is essential to guarantee the pat...

  • Article
  • Open Access
3 Citations
3,352 Views
16 Pages

Optimal Concentration and Duration of Endotracheal Tube Coating to Achieve Optimal Antimicrobial Efficacy and Safety Balance: An In Vitro Study

  • Manar Fathy Al-Sayed,
  • Mohamed Tarek El-Wakad,
  • Mohammed A. Hassan,
  • Ahmed M. Soliman and
  • Amal S. Eldesoky

16 May 2023

Background: Ventilator-associated pneumonia (VAP) is a common and genuine complication in fundamentally sick patients accepting mechanical ventilation. Silver nitrate sol-gel (SN) has been proposed as a potential preventative measure against VAP. Be...

  • Review
  • Open Access
20 Citations
4,055 Views
23 Pages

16 May 2023

Polymer gel materials are formed by physically crosslinking and chemically crosslinking to form a gel network system with high mechanical properties and reversible performance. Due to their excellent mechanical properties and intelligence, polymer ge...

  • Article
  • Open Access
6 Citations
4,350 Views
21 Pages

Clotrimazole-Loaded Borneol-Based In Situ Forming Gel as Oral Sprays for Oropharyngeal Candidiasis Therapy

  • Nutdanai Lertsuphotvanit,
  • Sarun Tuntarawongsa,
  • Kritamorn Jitrangsri and
  • Thawatchai Phaechamud

15 May 2023

Oral candidiasis encompasses fungal infections of the tongue and other oral mucosal sites with fungal overgrowth and its invasion of superficial oral tissues. Borneol was assessed in this research as the matrix-forming agent of clotrimazole-loaded in...

  • Article
  • Open Access
9 Citations
2,231 Views
14 Pages

15 May 2023

An efficient redox initiating system, ceric ammonium nitrate/nitric acid, has been employed for the first time to carry out photo-induced graft copolymerization of acrylonitrile (AN) onto sodium salt of partially carboxymethylated sodium alginate, ha...

  • Protocol
  • Open Access
1 Citations
3,037 Views
14 Pages

A LC-QTOF Method for the Determination of PEGDE Residues in Dermal Fillers

  • Giuseppe Alonci,
  • Anna Boussard,
  • Martina Savona,
  • Fabiana Cordella,
  • Gaetano Angelici,
  • Roberto Mocchi,
  • Sabrina Sommatis and
  • Damiano Monticelli

13 May 2023

Hyaluronic acid is one of the most important ingredients in dermal fillers, where it is often cross-linked to gain more favorable rheological properties and to improve the implant duration. Poly(ethylene glycol) diglycidyl ether (PEGDE) has been rece...

  • Article
  • Open Access
2 Citations
2,483 Views
14 Pages

Dielectric Study on Supramolecular Gels by Fiber Structure Formation from Low-Molecular-Weight Gelator/Water Mixtures

  • Kenta Shimizu,
  • Fumiya Abe,
  • Yasuhiro Kishi,
  • Rio Kita,
  • Naoki Shinyashiki and
  • Shin Yagihara

12 May 2023

There are various types of gel materials used in a wide range of fields, and their gelation mechanisms are extremely diverse. Furthermore, in the case of hydrogels, there exist some difficulties in understanding complicated molecular mechanisms espec...

  • Article
  • Open Access
14 Citations
2,468 Views
17 Pages

12 May 2023

The water absorption measurements of a novel superabsorbent anionic hydrogel, H-Na-PCMSA-g-PAN, has been reported first time in water with a poor conductivity, 0.15 M saline (NaCl, CaCl2, and AlCl3) solutions, and simulated urine (SU) solutions at va...

  • Article
  • Open Access
12 Citations
3,389 Views
19 Pages

Comparison of Different Aerogel Granules for Use as Aggregate in Concrete

  • Torsten Welsch,
  • Yannick Vievers,
  • Martina Schnellenbach-Held,
  • Danny Bialuschewski and
  • Barbara Milow

12 May 2023

In previous work of this group, a structural lightweight concrete was developed by embedding silica aerogel granules in a high-strength cement matrix. This concrete, called high-performance aerogel concrete (HPAC), is a lightweight building material...

  • Article
  • Open Access
3 Citations
3,164 Views
13 Pages

Superhydrophobic/Superoleophilic PDMS/SiO2 Aerogel Fabric Gathering Device for Self-Driven Collection of Floating Viscous Oil

  • Feng Liu,
  • Xin Di,
  • Xiaohan Sun,
  • Xin Wang,
  • Tinghan Yang,
  • Meng Wang,
  • Jian Li,
  • Chengyu Wang and
  • Yudong Li

12 May 2023

The persistent challenge of removing viscous oil on water surfaces continues to pose a major concern and requires immediate attention. Here, a novel solution has been introduced in the form of a superhydrophobic/superoleophilic PDMS/SiO2 aerogel fabr...

  • Article
  • Open Access
12 Citations
3,535 Views
23 Pages

New Photocrosslinked 3D Foamed Scaffolds Based on GelMA Copolymers: Potential Application in Bone Tissue Engineering

  • Jesús L. Pablos,
  • Javier Jiménez-Holguín,
  • Sandra Sánchez Salcedo,
  • Antonio J. Salinas,
  • Teresa Corrales and
  • María Vallet-Regí

11 May 2023

The production of customized polymeric hydrogels in the form of 3D scaffolds with application in bone tissue engineering is currently a topic of great interest. Based on gelatin methacryloyl (GelMa) as one of the most popular used biomaterials, GelMa...

  • Article
  • Open Access
4 Citations
2,389 Views
16 Pages

Probing the Effect of Young’s Modulus on the Reservoir Regulation Abilities of Dispersed Particle Gels

  • Zizhao Wang,
  • Zhixuan Zhu,
  • Tianyu Jiang,
  • Jinming Liu,
  • Yunbo Dong,
  • Yining Wu,
  • Mingwei Zhao,
  • Caili Dai and
  • Lin Li

11 May 2023

The mechanical strength of dispersed particle gels (DPGs), which can be directly characterized by Young’s modulus, is an important parameter affecting reservoir regulation performance. However, the effect of reservoir conditions on the mechanic...

  • Article
  • Open Access
26 Citations
3,795 Views
21 Pages

10 May 2023

Niosomes are multilamellar vesicles that effectively transfer active ingredients into the skin’s layers. To improve the active substance’s penetration across the skin, these carriers are frequently utilized as topical drug delivery system...

  • Article
  • Open Access
9 Citations
2,967 Views
19 Pages

10 May 2023

The aim of the present study is to formulate highly permeable carriers (i.e., transethosomes) for enhancing the delivery of prednisolone combined with tacrolimus for both topical and systemic pathological conditions. A Box–Behnken experimental...

  • Article
  • Open Access
5 Citations
2,522 Views
13 Pages

10 May 2023

Sucrose esters (SE) have been investigated as structuring agents in oleogels. Due to the low structuration power of SE as single agent, this component has recently been explored in combination with other oleogelators to form multicomponent systems. T...

  • Article
  • Open Access
13 Citations
2,709 Views
14 Pages

Biocompatible Glycol Chitosan Microgels as Effective Drug Carriers

  • Mehtap Sahiner,
  • Aynur S. Yilmaz,
  • Ramesh S. Ayyala and
  • Nurettin Sahiner

10 May 2023

Glycol chitosan (GC) is a chitosan (CH) derivative with improved water solubility with regards to CH which affords significant solubility advantages. In this study, microgels of GC as p(GC) were synthesized by a microemulsion technique at various cro...

  • Article
  • Open Access
18 Citations
5,243 Views
14 Pages

Effects of Alkaline Solvent Type and pH on Solid Physical Properties of Carrageenan from Eucheuma cottonii

  • Rival Ferdiansyah,
  • Marline Abdassah,
  • Achmad Zainuddin,
  • Revika Rachmaniar and
  • Anis Yohana Chaerunisaa

10 May 2023

The effects of alkali type and pH on the physical properties of carrageenan have been extensively studied. However, their effects on certain characteristics of solid-state properties of carrageenan have not been identified. This research aimed to inv...

  • Article
  • Open Access
23 Citations
6,249 Views
15 Pages

9 May 2023

We report the synthesis and characterization of poly (vinyl alcohol) (PVA)/Chitosan (CT) cryogels for applications involving the uptake and entrapment of particulate and bacterial colonies. In particular, we systematically investigated the network an...

  • Article
  • Open Access
4 Citations
2,595 Views
14 Pages

9 May 2023

Agarose hydrogel was enriched by chitosan as an active substance for the interactions with dyes. Direct blue 1, Sirius red F3B, and Reactive blue 49 were chosen as representative dyes for the study of the effect of their interaction with chitosan on...

  • Article
  • Open Access
25 Citations
5,814 Views
21 Pages

In Vitro and In Silico Characterization of Curcumin-Loaded Chitosan–PVA Hydrogels: Antimicrobial and Potential Wound Healing Activity

  • Hitesh Chopra,
  • Shabana Bibi,
  • Yugal Kishore Mohanta,
  • Tapan Kumar Mohanta,
  • Sandeep Kumar,
  • Inderbir Singh,
  • Muhammad Saad Khan,
  • Pradipta Ranjan Rauta,
  • Abdulrahman Alshammari and
  • Abdullah F. Alasmari
  • + 1 author

9 May 2023

Curcumin has been used in traditional medicine forages. The present study aimed to develop a curcumin-based hydrogel system and assess its antimicrobial potential and wound healing (WH) activity on an invitro and in silico basis. A topical hydrogel w...

  • Article
  • Open Access
22 Citations
5,819 Views
15 Pages

9 May 2023

As the market for plant-based meat analogs grows, the development of plant-based animal fat analogs has become increasingly important. In this study, we propose an approach by developing a gelled emulsion based on sodium alginate, soybean oil (SO), a...

  • Article
  • Open Access
3 Citations
2,850 Views
13 Pages

In-Situ Transformation of Li-ABW Zeolites Based on Li-Geopolymer

  • Huaiyuan Dou,
  • Quan Ye,
  • Yan He and
  • Xuemin Cui

9 May 2023

Lithium batteries, as energy storage devices, are playing an increasingly important role in human society. As a result of the low safety of the liquid electrolyte in batteries, more attention has been paid to solid electrolytes. Based on the applicat...

  • Article
  • Open Access
7 Citations
4,381 Views
18 Pages

Emulsion-Based Gel Loaded with Ibuprofen and Its Derivatives

  • Adebukola Abiola Agboola,
  • Anna Nowak,
  • Wiktoria Duchnik,
  • Łukasz Kucharski,
  • Anna Story,
  • Grzegorz Story,
  • Łukasz Struk,
  • Adrian Krzysztof Antosik and
  • Paula Ossowicz-Rupniewska

8 May 2023

The aim of this study was to evaluate the effect of vehicle and chemical modifications of the structure of active compounds on the skin permeation and accumulation of ibuprofen (IBU). As a result, semi-solid formulations in the form of an emulsion-ba...

  • Review
  • Open Access
11 Citations
3,616 Views
17 Pages

Cellulose-Based Metallogels—Part 1: Raw Materials and Preparation

  • Aleksandra Mikhailidi,
  • Irina Volf,
  • Dan Belosinschi,
  • Bogdan-Marian Tofanica and
  • Elena Ungureanu

8 May 2023

Metallogels are a class of materials produced by the complexation of polymer gels with metal ions that can form coordination bonds with the functional groups of the gel. Hydrogels with metal phases attract special attention due to the numerous possib...

  • Review
  • Open Access
26 Citations
4,742 Views
15 Pages

8 May 2023

Bone regenerative medicine is a clinical approach combining live osteoblast progenitors, such as mesenchymal stromal cells (MSCs), with a biocompatible scaffold that can integrate into host bone tissue and restore its structural integrity. Over the l...

  • Article
  • Open Access
10 Citations
3,050 Views
13 Pages

8 May 2023

A common problem associated with conventional gel breakers is that they can cause a premature reduction in gel viscosity at high temperatures. To address this, a urea-formaldehyde (UF) resin and sulfamic acid (SA) encapsulated polymer gel breaker was...

  • Article
  • Open Access
9 Citations
2,794 Views
16 Pages

Alginate-Bentonite-Based Hydrogels Designed to Obtain Controlled-Release Formulations of Dodecyl Acetate

  • Francisco Flores-Céspedes,
  • Matilde Villafranca-Sánchez and
  • Manuel Fernández-Pérez

6 May 2023

Dodecyl acetate (DDA), a volatile compound present in insect sex pheromones, was incorporated into alginate-based granules to obtain controlled-release formulations (CRFs). In this research, not only was the effect of adding bentonite to the basic al...

  • Review
  • Open Access
54 Citations
12,899 Views
42 Pages

Food-Grade Oleogels: Trends in Analysis, Characterization, and Applicability

  • Simona Perța-Crișan,
  • Claudiu-Ștefan Ursachi,
  • Bianca-Denisa Chereji,
  • Iolanda Tolan and
  • Florentina-Daniela Munteanu

6 May 2023

Currently, a large number of scientific articles can be found in the research literature in the field focusing on the use of oleogels for food formulation to improve their nutritional properties. The present review focuses on the most representative...

  • Article
  • Open Access
11 Citations
5,116 Views
16 Pages

Effects of Steam Sterilization on the Properties of Stimuli-Responsive Polymer-Based Hydrogels

  • Inês Ferreira,
  • Ana Camila Marques,
  • Paulo Cardoso Costa and
  • Maria Helena Amaral

6 May 2023

Hydrogels based on stimuli-responsive polymers can change their characteristics in response to small variations in environmental conditions, such as temperature, pH, and ionic strength, among others. In the case of some routes of administration, such...

  • Article
  • Open Access
3 Citations
3,312 Views
12 Pages

5 May 2023

The low ionic conductivity and unstable interface of electrolytes/electrodes are the key issues hindering the application progress of lithium-ion batteries (LiBs). In this work, a cross-linked gel polymer electrolyte (C-GPE) based on epoxidized soybe...

  • Article
  • Open Access
18 Citations
3,254 Views
20 Pages

Chitosan-Silica Hybrid Biomaterials for Bone Tissue Engineering: A Comparative Study of Xerogels and Aerogels

  • Antonio Pérez-Moreno,
  • Manuel Piñero,
  • Rafael Fernández-Montesinos,
  • Gonzalo Pinaglia-Tobaruela,
  • María V. Reyes-Peces,
  • María del Mar Mesa-Díaz,
  • José Ignacio Vilches-Pérez,
  • Luis Esquivias,
  • Nicolás de la Rosa-Fox and
  • Mercedes Salido

5 May 2023

Chitosan (CS) is a natural biopolymer that shows promise as a biomaterial for bone-tissue regeneration. However, because of their limited ability to induce cell differentiation and high degradation rate, among other drawbacks associated with its use,...

  • Feature Paper
  • Article
  • Open Access
7 Citations
2,541 Views
17 Pages

Tunability of Hybrid Silica Xerogels: Surface Chemistry and Porous Texture Based on the Aromatic Precursor

  • Beatriz Rosales-Reina,
  • Guillermo Cruz-Quesada,
  • Nataly Padilla-Postigo,
  • Marian Irigoyen-Razquin,
  • Ester Alonso-Martínez,
  • María Victoria López-Ramón,
  • Maialen Espinal-Viguri and
  • Julián J. Garrido

5 May 2023

The interest in new materials with specific properties has increased because they are essential for the environmental and technological needs of our society. Among them, silica hybrid xerogels have emerged as promising candidates due to their simple...

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Gels - ISSN 2310-2861