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Tomography, Volume 9, Issue 1

2023 February - 36 articles

Cover Story: The impacts of metal artifacts (MAs) on the contouring workload for head and neck radiotherapy have not yet been clarified. Therefore, we evaluated the relationship between the contouring time of the MA area and MAs on head and neck radiotherapy treatment planning. The contouring time of MAs showed moderate positive correlations with the MA volume and the number of CT images containing MAs. Interobserver reliability of the extracted MAs volume and contouring time were excellent and poor, respectively. From our results, it was suggested that the contouring time of MA areas is related to individual commitment rather than clinical experience. Therefore, the development of software combining metal artifact reduction methods with automatic contouring methods is necessary for reducing interobserver variability and contouring workload. View this paper
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Articles (36)

  • Article
  • Open Access
3 Citations
3,457 Views
10 Pages

19 February 2023

We investigated the effect of post-labeling delay (PLD) on the evaluation of brain tumor blood flow using arterial spin labeling (ASL) magnetic resonance (MR) imaging to assess the need for imaging with two PLDs. Retrospective analysis was conducted...

  • Article
  • Open Access
4 Citations
2,600 Views
16 Pages

Repeatability and Reproducibility Uncertainty in Magnetic Resonance-Based Electric Properties Tomography of a Homogeneous Phantom

  • Alessandro Arduino,
  • Francesca Pennecchi,
  • Ulrich Katscher,
  • Maurice Cox and
  • Luca Zilberti

17 February 2023

Uncertainty assessment is a fundamental step in quantitative magnetic resonance imaging because it makes comparable, in a strict metrological sense, the results of different scans, for example during a longitudinal study. Magnetic resonance-based ele...

  • Case Report
  • Open Access
2 Citations
3,428 Views
7 Pages

16 February 2023

Traumatic optic nerve injury may lead to almost instantaneous blindness. We describe a case of sight loss after a perforating injury to the eye. The case is unusual in that the patient remained conscious and the trauma to the eye was isolated. A full...

  • Article
  • Open Access
9 Citations
4,181 Views
15 Pages

14 February 2023

Breast cancer was the most diagnosed cancer around the world in 2020. Screening programs, based on mammography, aim to achieve early diagnosis which is of extreme importance when it comes to cancer. There are several flaws associated with mammography...

  • Article
  • Open Access
2 Citations
6,107 Views
11 Pages

[18F]FDG PET/CT: Lung Nodule Evaluation in Patients Affected by Renal Cell Carcinoma

  • Lighea Simona Airò Farulla,
  • Laura Lavinia Travaini,
  • Mariarosaria Cuomo,
  • Domenico Galetta,
  • Francesco Mattana,
  • Samuele Frassoni,
  • Giuseppe Buonsanti,
  • Lorenzo Muraglia,
  • Giulia Anna Zuccotti and
  • Francesco Ceci
  • + 2 authors

10 February 2023

Renal Cell Carcinoma (RCC) is generally characterized by low-FDG avidity, and [18F]FDG-PET/CT is not recommended to stage the primary tumor. However, its role to assess metastases is still unclear. The aim of this study was to evaluate the diagnostic...

  • Article
  • Open Access
6 Citations
4,723 Views
12 Pages

Evaluation of Apparent Diffusion Coefficient Repeatability and Reproducibility for Preclinical MRIs Using Standardized Procedures and a Diffusion-Weighted Imaging Phantom

  • Dariya Malyarenko,
  • Ghoncheh Amouzandeh,
  • Stephen Pickup,
  • Rong Zhou,
  • Henry Charles Manning,
  • Seth T. Gammon,
  • Kooresh I. Shoghi,
  • James D. Quirk,
  • Renuka Sriram and
  • Thomas L. Chenevert
  • + 5 authors

7 February 2023

Relevant to co-clinical trials, the goal of this work was to assess repeatability, reproducibility, and bias of the apparent diffusion coefficient (ADC) for preclinical MRIs using standardized procedures for comparison to performance of clinical MRIs...

  • Article
  • Open Access
2 Citations
4,427 Views
13 Pages

A Novel Approach to Determining Tumor Progression Using a Three-Site Pilot Clinical Trial of Spectroscopic MRI-Guided Radiation Dose Escalation in Glioblastoma

  • Karthik K. Ramesh,
  • Vicki Huang,
  • Jeffrey Rosenthal,
  • Eric A. Mellon,
  • Mohammed Goryawala,
  • Peter B. Barker,
  • Saumya S. Gurbani,
  • Anuradha G. Trivedi,
  • Alexander S. Giuffrida and
  • Brent D. Weinberg
  • + 8 authors

6 February 2023

Glioblastoma (GBM) is a fatal disease, with poor prognosis exacerbated by difficulty in assessing tumor extent with imaging. Spectroscopic MRI (sMRI) is a non-contrast imaging technique measuring endogenous metabolite levels of the brain that can ser...

  • Opinion
  • Open Access
8 Citations
3,884 Views
10 Pages

‘Ultrasound Examination’ of the Musculoskeletal System: Bibliometric/Visualized Analyses on the Terminology (Change)

  • Carmelo Pirri,
  • Nina Pirri,
  • Carla Stecco,
  • Veronica Macchi,
  • Andrea Porzionato,
  • Raffaele De Caro and
  • Levent Özçakar

2 February 2023

Ultrasound imaging of the musculoskeletal system is paramount for physicians of different specialties. In recent years, its use has become the extension of physical examinations like using a “magnifying glass”. Likewise, the eventual conc...

  • Article
  • Open Access
3 Citations
8,109 Views
10 Pages

T1-Weighted Contrast Enhancement, Apparent Diffusion Coefficient, and Cerebral-Blood-Volume Changes after Glioblastoma Resection: MRI within 48 Hours vs. beyond 48 Hours

  • Davide Negroni,
  • Romina Bono,
  • Eleonora Soligo,
  • Vittorio Longo,
  • Christian Cossandi,
  • Alessandro Carriero and
  • Alessandro Stecco

2 February 2023

Background: The aim of the study is to identify the advantages, if any, of post-operative MRIs performed at 48 h compared to MRIs performed after 48 h in glioblastoma surgery. Materials and Methods: To assess the presence of a residual tumor, the T1-...

  • Review
  • Open Access
15 Citations
6,396 Views
14 Pages

Advances in the Assessment of Coronary Artery Disease Activity with PET/CT and CTA

  • Jacek Kwiecinski,
  • Rafal Wolny,
  • Alicja Chwala and
  • Piotr Slomka

1 February 2023

Non-invasive testing plays a pivotal role in the diagnosis, assessment of progression, response to therapy, and risk stratification of coronary artery disease. Although anatomical plaque imaging by computed tomography angiography (CTA) and ischemia d...

  • Article
  • Open Access
2 Citations
5,148 Views
13 Pages

Structural Relationship between Cerebral Gray and White Matter Alterations in Degenerative Cervical Myelopathy

  • Chencai Wang,
  • Francesco Sanvito,
  • Talia C. Oughourlian,
  • Sabah Islam,
  • Noriko Salamon,
  • Langston T. Holly and
  • Benjamin M. Ellingson

31 January 2023

Patients with degenerative cervical myelopathy (DCM) undergo adaptive supraspinal changes. However, it remains unknown how subcortical white matter changes reflect the gray matter loss. The current study investigated the interrelationship between gra...

  • Article
  • Open Access
2 Citations
2,930 Views
16 Pages

Accelerated Simultaneous T2 and T2* Mapping of Multiple Sclerosis Lesions Using Compressed Sensing Reconstruction of Radial RARE-EPI MRI

  • Carl J. J. Herrmann,
  • Ludger Starke,
  • Jason M. Millward,
  • Joseph Kuchling,
  • Friedemann Paul and
  • Thoralf Niendorf

31 January 2023

(1) Background: Radial RARE-EPI MRI facilitates simultaneous T2 and T2* mapping (2in1-RARE-EPI). With modest undersampling (R = 2), the speed gain of 2in1-RARE-EPI relative to Multi-Spin-Echo and Multi-Gradient-Recalled-Echo references is limited. Fu...

  • Case Report
  • Open Access
6,681 Views
14 Pages

Ligamentum Flavum Rupture by Epidural Injection Using Ultrasound with SMI Method

  • Manabu Maeda,
  • Nana Maeda,
  • Keisuke Masuda,
  • Yoshiyuki Kamatani,
  • Shimizu Takamasa and
  • Yasuhito Tanaka

30 January 2023

The loss of resistance (LOR) method has been used exclusively to identify epidural space. It is difficult to find the epidural space without the risk of dural puncture. Various devices have been developed to improve the accuracy of the LOR method; ho...

  • Review
  • Open Access
4 Citations
4,986 Views
11 Pages

Labeling T Cells to Track Immune Response to Immunotherapy in Glioblastoma

  • John Y. Rhee,
  • Jack Y. Ghannam,
  • Bryan D. Choi and
  • Elizabeth R. Gerstner

30 January 2023

While the advent of immunotherapy has revolutionized cancer treatment, its use in the treatment of glioblastoma (GBM) has been less successful. Most studies using immunotherapy in GBM have been negative and the reasons for this are still being studie...

  • Article
  • Open Access
2 Citations
3,076 Views
10 Pages

Radiation Dose Assessment for Myocardial Perfusion Imaging: A Single Institution Survey

  • Essam Alkhybari,
  • Salman Albeshan,
  • Bandar Alanazi,
  • Raghad Alfarraj,
  • Rakan Alduhaim,
  • Intidhar El Bez Chanem and
  • Rima Tulbah

30 January 2023

Objective: This study aims to establish a local diagnostic reference level (LDRL) for single-photon emission tomography/computed tomography (SPECT/CT) and positron emission tomography/CT (PET/CT) with respect to myocardial perfusion imaging (MPI). Ma...

  • Article
  • Open Access
2 Citations
2,509 Views
9 Pages

30 January 2023

Acute lower extremity ischemia (ALI) is a cardiovascular emergency resulting from embolic and thrombotic causes. Although endovascular techniques have advanced, surgical thromboembolectomy is still the gold standard. Emergency thromboembolectomy surg...

  • Article
  • Open Access
3 Citations
6,727 Views
8 Pages

Can Intrapartum Ultrasonography Improve the Placement of the Vacuum Cup in Operative Vaginal Deliveries?

  • Rocio Garcia-Jimenez,
  • Irene Valero,
  • Carlota Borrero,
  • Jose Antonio Garcia-Mejido,
  • Ana Fernandez-Palacin,
  • Rosa Serrano and
  • Jose Antonio Sainz-Bueno

27 January 2023

Although the fetal head position has traditionally been evaluated by digital examination (DE), it has a failure rate ranging between 20 and 70%; hence, intrapartum transabdominal ultrasonography (TUS) has become relevant. We aimed to evaluate the uti...

  • Review
  • Open Access
16 Citations
6,511 Views
30 Pages

Diagnostic Management of Gastroenteropancreatic Neuroendocrine Neoplasms: Technique Optimization and Tips and Tricks for Radiologists

  • Fabio Pellegrino,
  • Vincenza Granata,
  • Roberta Fusco,
  • Francesca Grassi,
  • Salvatore Tafuto,
  • Luca Perrucci,
  • Giulia Tralli and
  • Mariano Scaglione

27 January 2023

Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) comprise a heterogeneous group of neoplasms, which derive from cells of the diffuse neuroendocrine system that specializes in producing hormones and neuropeptides and arise in most cases spor...

  • Review
  • Open Access
63 Citations
18,760 Views
22 Pages

Pros and Cons of Dual-Energy CT Systems: “One Does Not Fit All”

  • Ana P. Borges,
  • Célia Antunes and
  • Luís Curvo-Semedo

27 January 2023

Dual-energy computed tomography (DECT) uses different energy spectrum x-ray beams for differentiating materials with similar attenuation at a certain energy. Compared with single-energy CT, it provides images with better diagnostic performance and a...

  • Article
  • Open Access
14 Citations
6,987 Views
17 Pages

Dual Magnetic Particle Imaging and Akaluc Bioluminescence Imaging for Tracking Cancer Cell Metastasis

  • Ryan J. Williams,
  • Olivia C. Sehl,
  • Julia J. Gevaert,
  • Shirley Liu,
  • John J. Kelly,
  • Paula J. Foster and
  • John A. Ronald

25 January 2023

Magnetic particle imaging (MPI) provides hotspot tracking and direct quantification of superparamagnetic iron oxide nanoparticle (SPIO)-labelled cells. Bioluminescence imaging (BLI) with the luciferase reporter gene Akaluc can provide complementary i...

  • Review
  • Open Access
19 Citations
6,415 Views
12 Pages

Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned?

  • Chiara Pozzessere,
  • Christophe von Garnier and
  • Catherine Beigelman-Aubry

24 January 2023

Lung cancer screening (LCS) programs through low-dose Computed Tomography (LDCT) are being implemented in several countries worldwide. Radiation exposure of healthy individuals due to prolonged CT screening rounds and, eventually, the additional exam...

  • Article
  • Open Access
9 Citations
6,096 Views
12 Pages

15 January 2023

Background: Multidetector computer tomography (CT) has been used to diagnose pathologies such as osteoporosis via opportunistic screening, where the assessment of the bone structure and the measurement of bone mineral density (BMD) are of great relev...

  • Article
  • Open Access
3 Citations
5,040 Views
11 Pages

A Combined Region- and Pixel-Based Deep Learning Approach for Quantifying Abdominal Adipose Tissue in Adolescents Using Dixon Magnetic Resonance Imaging

  • Olanrewaju A. Ogunleye,
  • Harish Raviprakash,
  • Ashlee M. Simmons,
  • Rhasaan T.M. Bovell,
  • Pedro E. Martinez,
  • Jack A. Yanovski,
  • Karen F. Berman,
  • Peter J. Schmidt,
  • Elizabeth C. Jones and
  • Li-Yueh Hsu
  • + 2 authors

15 January 2023

Background: The development of adipose tissue during adolescence may provide valuable insights into obesity-associated diseases. We propose an automated convolutional neural network (CNN) approach using Dixon-based magnetic resonance imaging (MRI) to...

  • Article
  • Open Access
8 Citations
6,589 Views
9 Pages

Comparison between PSMA PET/CT and MRI for Characterizing Hepatocellular carcinoma: A Real-World Study

  • Veronica Chi Ken Wong,
  • Joshua Yip,
  • Vincenzo Fragomeli,
  • Martin Weltman,
  • Han Loh,
  • Ken Le,
  • Diep Nguyen,
  • Chuong Bui and
  • Robert Mansberg

13 January 2023

Prostate specific membrane antigen (PSMA) is expressed by hepatocellular carcinoma (HCC). PSMA PET/CT has potential as an imaging agent for the detection of HCC including early diagnosis and monitoring for recurrence following surgical resection. Thi...

  • Article
  • Open Access
13 Citations
5,114 Views
25 Pages

Radiation-Free Microwave Technology for Breast Lesion Detection Using Supervised Machine Learning Model

  • Soumya Prakash Rana,
  • Maitreyee Dey,
  • Riccardo Loretoni,
  • Michele Duranti,
  • Mohammad Ghavami,
  • Sandra Dudley and
  • Gianluigi Tiberi

12 January 2023

Mammography is the gold standard technology for breast screening, which has been demonstrated through different randomized controlled trials to reduce breast cancer mortality. However, mammography has limitations and potential harms, such as the use...

  • Article
  • Open Access
3 Citations
3,876 Views
7 Pages

The Relationship between the Contouring Time of the Metal Artifacts Area and Metal Artifacts in Head and Neck Radiotherapy

  • Kouji Katsura,
  • Satoshi Tanabe,
  • Hisashi Nakano,
  • Madoka Sakai,
  • Atsushi Ohta,
  • Motoki Kaidu,
  • Marie Soga,
  • Taichi Kobayashi,
  • Masaki Takamura and
  • Takafumi Hayashi

11 January 2023

(1) Background: The impacts of metal artifacts (MAs) on the contouring workload for head and neck radiotherapy have not yet been clarified. Therefore, this study evaluated the relationship between the contouring time of the MAs area and MAs on head a...

  • Article
  • Open Access
5 Citations
3,127 Views
9 Pages

Multilesion Segmentations in Patients with Intracerebral Hemorrhage: Reliability of ICH, IVH and PHE Masks

  • Estelle Vogt,
  • Ly Huong Vu,
  • Haoyin Cao,
  • Anna Speth,
  • Dmitriy Desser,
  • Frieder Schlunk,
  • Andrea Dell’Orco and
  • Jawed Nawabi

11 January 2023

Background and Purpose: Fully automated methods for segmentation and volume quantification of intraparenchymal hemorrhage (ICH), intraventricular hemorrhage extension (IVH), and perihematomal edema (PHE) are gaining increasing interest. Yet, reliabil...

  • Article
  • Open Access
3 Citations
2,310 Views
19 Pages

Measurement of Charge and Refractive Indices in Optically Trapped and Ionized Living Cells

  • Endris Muhammed,
  • Daniel B. Erenso,
  • Ying Gao,
  • Li Chen,
  • Michele Kelley,
  • Carina Vazquez,
  • Mitchell Gale,
  • Cody Nichols and
  • Horace T. Crogman

29 December 2022

The post-ionization dynamics of chemo-treated and untreated 4T1 breast cancer cells ionized by laser trapping techniques are studied. We have determined each cell’s charge and refractive index by developing a theoretical model for the forces de...

  • Article
  • Open Access
3 Citations
4,966 Views
10 Pages

29 December 2022

This study aimed to optimize velocity-selective magnetic resonance angiography (VS-MRA) protocols for whole-neck angiography and demonstrate its feasibility in healthy subjects with comparisons to clinical 3D time-of-flight (TOF) angiography. To help...

  • Article
  • Open Access
7 Citations
4,514 Views
10 Pages

Stereotactic Microwave Ablation of Hepatocellular Carcinoma: The Impact of Tumor Size and Minimal Ablative Margin on Therapeutic Success

  • Antonia-Maria Pausch,
  • Tamam Ghali,
  • Tobias Wertheimer,
  • Florian Zeman,
  • Karolina Mueller,
  • Michael Christian Doppler,
  • Ingo Einspieler,
  • Lukas Philipp Beyer,
  • Stephan Schleder and
  • Lukas Luerken
  • + 1 author

26 December 2022

Background: Microwave ablation (MWA) has gained relevance in the treatment of hepatic malignancies and especially in hepatocellular carcinoma (HCC), and it is an important alternative to surgery. The purpose of the study was to evaluate whether the m...

  • Article
  • Open Access
2 Citations
2,640 Views
14 Pages

Myocardial Contractility Pattern Characterization in Radiation-Induced Cardiotoxicity Using Magnetic Resonance Imaging: A Pilot Study with ContractiX

  • El-Sayed H. Ibrahim,
  • Antonio Sosa,
  • Sherry-Ann Brown,
  • Dayeong An,
  • Slade Klawikowski,
  • John Baker and
  • Carmen Bergom

22 December 2022

Radiation therapy (RT) plays an integral role in treating thoracic cancers, despite the risk of radiation-induced cardiotoxicity. We hypothesize that our newly developed magnetic resonance imaging (MRI)-based contractility index (ContractiX) is a sen...

  • Article
  • Open Access
5 Citations
3,804 Views
11 Pages

22 December 2022

(1) Background: This study investigates the early evaluation value of magnetic resonance imaging (MRI) and multidetector computed tomography (MDCT) in diagnosing the recurrence of bladder cancer (BC) after trans-urethral resection (TUR) alone or comb...

  • Article
  • Open Access
1 Citations
4,853 Views
13 Pages

Reduction in Radiation Exposure in Minimally Invasive Pedicle Screw Placement Using a Tubular Retractor: A Pilot Study

  • Takeshi Oki,
  • Alan Kawarai Lefor,
  • Kentaro Nakamura,
  • Takahiro Higashi and
  • Isao Oki

20 December 2022

Background and Objectives: Percutaneous pedicle screw (PPS) placement is a minimally invasive spinal procedure that has been rapidly adopted over the last decade. However, PPS placement has elicited fear of increased radiation exposure from some surg...

  • Article
  • Open Access
7 Citations
4,735 Views
11 Pages

20 December 2022

The prediction of an occult invasive component in ductal carcinoma in situ (DCIS) before surgery is of clinical importance because the treatment strategies are different between pure DCIS without invasive component and upgraded DCIS. We demonstrated...

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Tomography - ISSN 2379-139X