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14 November 2018

Ultrasound-Assisted One Pot Synthesis of Novel 5-(1-(Substituted phenyl)-4,5-diphenyl-1H-imidazol-2-yl)-4-methylthiazole †

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1
Maulana Azad Post Graduate and Research Centre, Rafiq Zakaria Campus, Rauza Baug, Aurangabad 431001, India
2
Departamento de Química Orgánica, Facultad de Ciencias, Universidad of Santiago de Compostela, Alfonso X el Sabio, 27002 Lugo, Spain
3
Wilson College, Girgaon Chawpatty, Mumbai 400007, India
*
Author to whom correspondence should be addressed.
Proceedings2019, 9(1), 63;https://doi.org/10.3390/ecsoc-22-05795
This article belongs to the Proceedings 22nd International Electronic Conference on Synthetic Organic Chemistry
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Abstract

This work reports synthesis of ten novel derivatives of 5-(1-(substituted phenyl)-4,5-diphenyl-1H-imidazol-2-yl)-4-methylthiazole 5(a–o). The reaction of benzil, primary aryl amines, 4-methylthiazole-5-carbaldehyde and ammonium acetate was carried out in one pot in the presence of eco-friendly catalyst Ceric ammonium nitrate in solvent ethanol to give final compounds. The structures of the synthesized compounds were confirmed by spectral characterization such as IR, 1H-NMR, 13C-NMR and mass spectral studies.

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