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  • Clinical and Translational Neuroscience is published by MDPI from Volume 5 Issue 2 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with SAGE.
  • Review
  • Open Access

1 June 2021

Myocardial Injury in Acute Ischemic Stroke

,
and
1
Klinik für Neurologie mit Experimenteller Neurologie and Center for Stroke Research Berlin (CSB), Charité-Universitätsmedizin Berlin, Hindenburgdamm 30, 12203 Berlin, Germany
2
Berlin Institute of Health (BIH), 10178 Berlin, Germany
3
German Center for Cardiovascular Research (Deutsches Zentrum für Herz-Kreislaufforschung; DZHK), Partner Site Berlin, 10785 Berlin, Germany
4
German Center for Neurodegenerative Diseases (Deutsches Zentrum für Neurodegenerative Erkrankungen; DZNE), Partner Site Berlin, 10117 Berlin, Germany

Abstract

Since antiquity, the interaction of brain and heart has inspired physicians and philosophers. Today, our knowledge has vastly improved, but the exact way of their interaction still holds many secrets to reveal. The interaction between brain and heart merits particular attention in the aftermath of a sudden injury to the brain-like acute ischemic stroke (AIS). This narrative review gives an overview of current knowledge on frequency, prognosis, and potential pathophysiological mechanisms of myocardial injury following AIS.

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