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Oral, Volume 5, Issue 3

2025 September - 26 articles

Cover Story: Periodontal disease is a significant oral health concern worldwide, particularly amongst individuals living with the human immunodeficiency virus (HIV). Biological aging is associated with a natural decline in the immune system, which can also affect the severity of periodontitis. In people living with HIV (PLWH), the contribution of both the HIV infection and the aging process can lead to increased susceptibility to periodontal disease. This paper reviewed recent literature about the relationships between HIV infection and early aging and their impact on periodontitis. This exploration through molecular and cellular mechanisms underlying the relationships between aging, HIV, and periodontitis can provide therapeutic implications for dental clinicians to prevent and treat their affected patients. View this paper
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Articles (26)

  • Review
  • Open Access
2,024 Views
18 Pages

Analgesic Efficacy of Postoperative Ibuprofen in Third Molar Surgery: A Meta-Analysis

  • Itzel Joselyn Mora-Falcón,
  • Iván Agustín Amador-Beas,
  • Ronell Bologna-Molina,
  • Nelly Molina-Frechero,
  • Othoniel Hugo Aragón-Martínez,
  • Nicolás Serafín-Higuera,
  • Sandra López-Verdín and
  • Mario Alberto Isiordia-Espinoza

18 September 2025

Purpose: The aim of this study is to determine the analgesic efficacy of ibuprofen 200, 400, and 600 mg after lower third molar surgery. Material and Methods: Clinical trials that included patients undergoing third molar surgery comparing ibuprofen w...

  • Article
  • Open Access
1,181 Views
11 Pages

Income Inequalities and Dental Caries in 12-Year-Olds: An Ecological Comparison Between a High- and a Lower-Middle-Income Country

  • Dilini Lalanthi Ratnayake,
  • Wayne Richards,
  • Jamal Ameen,
  • Anne-Marie Coll and
  • Teresa Filipponi

9 September 2025

Background/Objectives: This study aimed to assess whether income was associated with dental caries experience and dental care levels among 12-year-old children in two contrasting economic contexts, Sri Lanka (lower-middle-income) and Wales (high-inco...

  • Systematic Review
  • Open Access
1,295 Views
13 Pages

Bond Strength of Impression Materials to Conventional and Additively Manufactured Custom Tray Materials: A Systematic Review

  • Petra Clarkson,
  • Xiaoyun Liu,
  • Andrew B. Cameron,
  • John M. Aarts and
  • Joanne J. E. Choi

8 September 2025

Purpose: We aimed to systematically review the current literature on the bond strength between custom tray materials and impression materials, including the various parameters affecting the strength. Methods: Four electronic databases were used: Ovid...

  • Article
  • Open Access
1,956 Views
26 Pages

Oral Lesions in a Teaching Clinic: A Retrospective Study and Systematic Review

  • Luke Wandzura,
  • Michelle Sperandio,
  • Melanie Hamilton and
  • Felipe F. Sperandio

8 September 2025

Background/Objectives: Oral lesions can present with a wide range of clinical appearances, often making diagnosis challenging, particularly for dental students. This study aimed to identify the most common oral lesions treated at a teaching dental cl...

  • Review
  • Open Access
3,458 Views
15 Pages

5 September 2025

Peri-implantitis is marked by ongoing bone loss and soft tissue inflammation surrounding dental implants. Due to its ability to intensify tissue healing and its compatibility with the body, hyaluronic acid (HA) has appeared as a viable biomaterial fo...

  • Systematic Review
  • Open Access
1,333 Views
22 Pages

Bidirectional Relationship Between Periodontal Disease and Reproductive Disorders: Focus on Polycystic Ovary Syndrome

  • Francesca Angiolani,
  • Davide Gerardi,
  • Sara Bernardi,
  • Diana Torge,
  • Serena Bianchi,
  • Maurizio Piattelli and
  • Giuseppe Varvara

5 September 2025

Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by hyperandrogenism, irregular ovulation, and polycystic ovarian morphology. The severity of periodontal inflammation in PCOS may be linked to elevated levels of infl...

  • Review
  • Open Access
2 Citations
3,120 Views
33 Pages

Composition and Interactions of the Oral–Gastrointestinal Microbiome Populations During Health, Disease, and Long-Duration Space Missions: A Narrative Review

  • Mahmoud M. Bakr,
  • Gabrielle M. Caswell,
  • Mahmoud Al Ankily,
  • Sarah I. Zeitoun,
  • Nada Ahmed,
  • Mohammed Meer and
  • Mohamed Shamel

3 September 2025

All forms of life on Earth are dependent on microbes. In vertebrates, the oral cavity and the gastrointestinal tract are colonized by large numbers of microorganisms, which includes species from many life forms: bacteria, fungi, archaea, and protozoa...

  • Article
  • Open Access
1,756 Views
23 Pages

Trauma, Terror, and Toothpaste: Exploring Memories for Dental Visits Across a Range of Patient Fear

  • Kelly A. Daly,
  • Jennie Ochshorn,
  • Richard E. Heyman,
  • Ronni D. Lipnitsky,
  • Suher Baker,
  • Adrianna O. Rozbicka,
  • Sidhant Athilat and
  • Allan Pike

1 September 2025

Background/Objectives: Emotional fear memories are increasingly recognized as contributors to the development of specific fears and phobias. Despite this, relatively little dental fear research has specifically focused on patient memories or their po...

  • Review
  • Open Access
4 Citations
2,302 Views
18 Pages

The Impact of HIV Infection and Aging on Periodontitis

  • Sophia DeVore,
  • Dalia Seleem and
  • Miou Zhou

1 September 2025

Background: Periodontal disease is a common chronic inflammatory disease affecting the oral cavity involving the tissues supporting teeth. It is a significant oral health concern worldwide, particularly amongst individuals living with human immunodef...

  • Systematic Review
  • Open Access
3 Citations
3,808 Views
24 Pages

Wet vs. Dry Dentin Bonding: A Systematic Review and Meta-Analysis of Adhesive Performance and Hybrid Layer Integrity

  • Mircea Popescu,
  • Mădălina Malița,
  • Andrei Vorovenci,
  • Andreea Angela Ștețiu,
  • Viorel Ștefan Perieanu,
  • Radu Cătălin Costea,
  • Mihai David,
  • Raluca Mariana Costea,
  • Maria Antonia Ștețiu and
  • Mihai Burlibașa
  • + 4 authors

28 August 2025

Objective: This systematic review and meta-analysis aimed to evaluate the effects of moisture control strategies (including wet-bonding techniques, universal adhesives, and etching type) on dentin bonding performance in restorative dentistry. Methods...

  • Article
  • Open Access
1 Citations
1,996 Views
9 Pages

Effects of Mandibular Advancement Device on Cardiovascular and Respiratory Parameters in OSA Patients

  • Domenico Ciavarella,
  • Donatella Ferrara,
  • Carlotta Fanelli,
  • Fariba Esperouz,
  • Carlotta Burlon,
  • Giuseppe Burlon,
  • Lucio Lo Russo,
  • Michele Tepedino and
  • Mauro Lorusso

22 August 2025

Background: Mandibular advancement devices (MADs) are considered an effective therapeutic option for managing obstructive sleep apnea syndrome (OSAS) in adults. Obstructive sleep apnea (OSA) is associated with a range of comorbidities, notably cardio...

  • Review
  • Open Access
2,155 Views
18 Pages

The Obesity–Periodontitis Axis: Microbial Mechanisms and Clinical Implications

  • Evelyn Lins Araújo,
  • Lorena Abreu Fernandes,
  • Tamires Szeremeske Miranda and
  • Sabri Saeed Sanabani

18 August 2025

Background: Obesity and periodontitis are two chronic inflammatory diseases with a bidirectional relationship possibly mediated by microbial and immunologic signaling pathways. This narrative review aims to investigate how microbial dysbiosis and inf...

  • Review
  • Open Access
1,391 Views
12 Pages

Adjunctive Use of Biologics in Alveolar Ridge Preservation: A Narrative Review

  • Celine Soon,
  • Pradeep Koppolu and
  • Leticia Algarves Miranda

15 August 2025

Background: The purpose of alveolar ridge preservation (ARP) is to minimise the physiological alveolar ridge reduction occurring after dental extraction, which can prevent the need for future alveolar ridge augmentation. Biologic materials (biologics...

  • Case Report
  • Open Access
1 Citations
2,609 Views
7 Pages

Brown Tumor in Jaw Associated with Hyperparathyroidism: A Case Report

  • Verónica Montserrat Silva-Gutiérrez,
  • Judith Berenice Macías-Jiménez,
  • Adriana Molotla-Fragoso,
  • Claudia Patricia Mejía-Velázquez,
  • Gabriel Levi Estévez-González and
  • Luis Fernando Jacinto-Alemán

14 August 2025

Background/Objectives: Brown tumors are bone manifestations of hyperparathyroidism, and they are characterized by histologic similarities with Central Giant Cell Granuloma (CGCG). Their diagnosis requires clinical, microscopic, macroscopic, and serol...

  • Article
  • Open Access
1,372 Views
11 Pages

Proposal of a Cephalometric Method in Computed Tomography to Mandibular Analysis in Infants with Pierre Robin Sequence Treated by Fast and Early Mandibular Osteo-Distraction: Pilot Study

  • Francesca Imondi,
  • Adriana Assunta De Stefano,
  • Rachele Podda,
  • Martina Horodynski,
  • Roberto Antonio Vernucci,
  • Valentina Mazzoli,
  • Piero Cascone and
  • Gabriella Galluccio

13 August 2025

Background: Newborns with Pierre Robin Sequence (PRS) usually show varying degrees of upper airway obstruction and difficulty feeding due to severe micrognatia. Mandibular distraction osteogenesis has become popular as an alternative treatment option...

  • Case Report
  • Open Access
1 Citations
2,350 Views
12 Pages

Oral Rehabilitation Following Surgical Treatment of Mandibular Ameloblastoma: Case Report and Comprehensive Literature Review

  • Sepideh Goudarzi,
  • Chiara Cinquini,
  • Rossana Izzetti,
  • Marco Nisi,
  • Mattia Priami,
  • Bruno Carlo Brevi,
  • Luca Bruschini,
  • Fulvio Lorenzetti,
  • Simonetta Santarelli and
  • Antonio Barone

8 August 2025

Objectives: Ameloblastoma is a locally aggressive odontogenic tumor of the jaws characterized by a high recurrence rate. This work aims to present our clinical experience in managing patient oral rehabilitation following an extensive mandibular amelo...

  • Review
  • Open Access
2 Citations
2,324 Views
13 Pages

Salivary Biomarkers for Early Detection of Autism Spectrum Disorder: A Scoping Review

  • Margherita Tumedei,
  • Niccolò Cenzato,
  • Sourav Panda,
  • Funda Goker and
  • Massimo Del Fabbro

4 August 2025

Background: Autism spectrum disorder (ASD) represents a neurobiological disorder with a high prevalence in the children’s population. The aim of the present review was to assess the current evidence on the use of salivary biomarkers for the ear...

  • Review
  • Open Access
4 Citations
4,374 Views
15 Pages

1 August 2025

Background: Obstructive sleep apnea (OSA) is a prevalent disorder in both pediatric and adult populations, characterized by substantial morbidity encompassing cardiovascular, neurocognitive, and metabolic impairments. Management strategies vary by ag...

  • Article
  • Open Access
2,759 Views
15 Pages

29 July 2025

Objectives: Torus mandibularis (TM) is a benign bony exostosis on the lingual surface of the mandible, typically developing from the third decade of life with slow progression; its etiology remains unclear. As TM excision causes no functional or aest...

  • Review
  • Open Access
2,309 Views
16 Pages

Topical Oxygen Therapy (blue®m) for Post-Surgical Care Protocols to Promote Wound Healing in Periodontology and Dental Implants: A Case-Based Literature Review

  • Cristian Scognamiglio,
  • Alessandro Perucchi,
  • Chalini Sundar,
  • Tatiana Miranda Deliberador and
  • Hamdan Alghamdi

29 July 2025

Background: Stable post-surgical wound healing surrounding teeth and dental implants is essential for achieving excellent clinical outcomes, both during the initial phases of treatment and over the long term. Objectives: This work follows the new eme...

  • Review
  • Open Access
1 Citations
2,955 Views
19 Pages

24 July 2025

Background/Objectives: Emerging evidence links diabetes to increased cancer risk. This study aimed to assess the association between diabetes mellitus (DM)(type 1, type 2, or gestational) and the development of head and neck cancer. Methods: An umbre...

  • Article
  • Open Access
1,787 Views
11 Pages

10 July 2025

Background: Periodontitis is a chronic inflammatory disease influenced by host aging, yet the specific effects of aging on disease susceptibility remain unclear. Objective: This study aimed to evaluate whether aging increases susceptibility to Porphy...

  • Article
  • Open Access
1,105 Views
13 Pages

Experiences and Attitudes Toward the Treatment of Patients with Mental Disorders Among Dentists in Croatia: A Cross-Sectional Pilot Study

  • Branimir Ninčević,
  • Antonija Tadin,
  • Marija Franka Žuljević and
  • Tina Poklepović Peričić

10 July 2025

Background: The aim of this study was to assess the experiences and attitudes of dentists toward treating patients with mental disorders and to investigate how these attitudes correlate with factors such as sex, age, and years of clinical experience....

  • Review
  • Open Access
3,002 Views
14 Pages

8 July 2025

Objectives: This review examines the efficacy of each laser type in the field of periodontal surgery and analyzes published articles that focus on the use of lasers in periodontal surgery. Methods: Automatic and manual searches were made in 3 separat...

  • Article
  • Open Access
1,522 Views
12 Pages

Effects of Functional Therapy in Patients Affected by Craniofacial Microsomia: A Retrospective Study

  • Ersilia Leontini,
  • Martina Mezio,
  • Roberto Antonio Vernucci,
  • Roberto Di Giorgio,
  • Gabriella Galluccio and
  • Ersilia Barbato

2 July 2025

Background/Objectives: Craniofacial microsomia (CFM), previously known as hemifacial microsomia, is a congenital condition involving structures derived from the first and second pharyngeal arches. CFM is characterized by asymmetrical craniofacial gro...

  • Review
  • Open Access
10,146 Views
18 Pages

Can New Remineralizing Agents Serve as Fluoride Alternatives in Caries Prevention? A Scoping Review

  • Jekaterina Gudkina,
  • Bennett T. Amaechi,
  • Stephen H. Abrams and
  • Anda Brinkmane

2 July 2025

Background: Due to limitations of fluoride (F) treatment as a main caries preventive measure, it is important to consider the use of other dental caries preventive measures to reduce caries prevalence, especially in its early stages. Recently, new re...

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Oral - ISSN 2673-6373