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Most Cited

  • Review
  • Open Access
22 Citations
8,954 Views
19 Pages

Salivary Biomarkers Identification: Advances in Standard and Emerging Technologies

  • Vlad Constantin,
  • Ionut Luchian,
  • Ancuta Goriuc,
  • Dana Gabriela Budala,
  • Florinel Cosmin Bida,
  • Cristian Cojocaru,
  • Oana-Maria Butnaru and
  • Dragos Ioan Virvescu

9 April 2025

Introduction: Salivary biomarkers have been extensively studied in relation to oral disease, such as periodontal disease, oral cancer, and dental caries, as well as systemic conditions including diabetes, cardiovascular diseases, and neurological dis...

  • Article
  • Open Access
18 Citations
4,553 Views
15 Pages

One-Stage Methods of Computer Vision Object Detection to Classify Carious Lesions from Smartphone Imaging

  • S. M. Siamus Salahin,
  • M. D. Shefat Ullaa,
  • Saif Ahmed,
  • Nabeel Mohammed,
  • Taseef Hasan Farook and
  • James Dudley

4 April 2023

The current study aimed to implement and validate an automation system to detect carious lesions from smartphone images using different one-stage deep learning techniques. 233 images of carious lesions were captured using a smartphone camera system a...

  • Systematic Review
  • Open Access
17 Citations
10,635 Views
12 Pages

Malignant Transformation of Oral Lichen Planus—An Umbrella Study of Systematic Reviews

  • Saman Warnakulasuriya,
  • Pablo Ramos-García and
  • Miguel Ángel González-Moles

3 July 2023

Oral lichen planus (OLP) is classified as a potentially malignant disorder. Systematic reviews collating longitudinal observation studies provide evidence of the rate or proportion of malignant transformation. We conducted an umbrella study of publis...

  • Feature Paper
  • Review
  • Open Access
13 Citations
8,285 Views
11 Pages

3 April 2023

The use of digital health technologies, including telemedicine and teledentistry, has become a necessity in healthcare due to the SARS-CoV-19 pandemic. These technologies allow for the reduction of the workload of healthcare providers and the improve...

  • Feature Paper
  • Article
  • Open Access
12 Citations
5,127 Views
19 Pages

3 August 2023

Triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA), two resin monomers often used in dental restorative materials, are leached due to insufficient polymerization and contact cells of the oral cavity. Despite reports on...

  • Article
  • Open Access
10 Citations
4,509 Views
11 Pages

Mechanical Properties of Direct Composite Resins and CAD/CAM Composite Blocks

  • João Carlos Ramos,
  • Alfredo Marinho,
  • Ana Messias,
  • Gabriela Almeida,
  • Alexandra Vinagre and
  • Ricardo Dias

3 May 2024

The widespread application of CAD/CAM technology in contemporary dentistry led to the development of promising restorative materials, such as resin composite blocks (RCBs). Thus, the present study aims to evaluate the mechanical properties of RCBs, c...

  • Feature Paper
  • Review
  • Open Access
9 Citations
11,399 Views
27 Pages

27 November 2023

A partial or complete pulpotomy is a type of vital pulp therapy (VPT) that aims to remove the inflamed, infected pulp, leaving behind healthy, vital pulp that is capable of healing. VPT has gained renewed popularity as a treatment option in permanent...

  • Review
  • Open Access
8 Citations
5,620 Views
22 Pages

The Influence of Polishing on the Mechanical Properties of Zirconia—A Systematic Review

  • Xiaoyun Liu,
  • John M. Aarts,
  • Sunyoung Ma and
  • Joanne Jung Eun Choi

13 March 2023

Purpose: To systematically review studies that investigated the consequences of various polishing protocols on the mechanical properties of zirconia. The effects on the roughness and crystalline phase transformation were also evaluated. Materials and...

  • Review
  • Open Access
8 Citations
11,402 Views
20 Pages

Silicon-, Silica-, and Silicate-Toothpastes for Remineralization and Repair of Teeth: A Scoping Review

  • Fabio Correia Sampaio,
  • Andressa Feitosa Bezerra de Oliveira,
  • Nayanna Lana Soares Fernandes,
  • Ana Carolina Cheron Gentile,
  • Giovanna Bueno Marinho,
  • Marcelo José Strazzeri Bönecker,
  • Marco Aurelio Benini Paschoal,
  • Paulo Henrique Perlatti D’Alpino and
  • Fabiano Vieira Vilhena

15 October 2024

Objective: The purpose of this scoping review was to identify gaps in the literature and summarize findings from studies examining the use of silicon-, silica-, and silicate-based toothpastes for the remineralization and repair of mineralized tooth t...

  • Article
  • Open Access
8 Citations
3,251 Views
13 Pages

Role of Glutathione in Neutrophil Chemotaxis in Periodontitis

  • Nurul Iman Binti Badlishah Sham and
  • Melissa M. Grant

23 November 2023

Periodontitis is a common non-communicable inflammatory disease that leads to the destruction of periodontal tissues and tooth loss. Initiated by the plaque biofilm, there is a strong innate immune response with an abundance of neutrophils in the per...

  • Review
  • Open Access
8 Citations
16,204 Views
32 Pages

Experiences with Cling Film and Dental Dam Use in Oral Sex: A Mixed-Methods Systematic Review

  • Kehinde Kazeem Kanmodi,
  • Eyinade Adeduntan Egbedina,
  • Misheck Julian Nkhata and
  • Lawrence Achilles Nnyanzi

17 May 2023

This study aimed to conduct a mixed-methods SR of the literature investigating the experiences (knowledge, attitudes, practices, and effects of use) concerning dental dam and cling film use. The SR methodology was informed by the Preferred Reporting...

  • Review
  • Open Access
7 Citations
3,198 Views
24 Pages

The Role of Tissue Engineering in Orthodontic and Orthognathic Treatment: A Narrative Review

  • Rosana Farjaminejad,
  • Samira Farjaminejad,
  • Melika Hasani,
  • Franklin Garcia-Godoy,
  • Babak Sayahpour,
  • Anand Marya and
  • Abdolreza Jamilian

20 March 2025

Background: Orthodontics and orthognathic surgery present challenges such as extended treatment durations, patient discomfort, and complications like root resorption. Recent advancements in tissue engineering and nanotechnology offer promising soluti...

  • Review
  • Open Access
7 Citations
10,132 Views
26 Pages

2 April 2025

Three-dimensional (3D) printing is transforming dentistry by enabling precise and personalized treatments in prosthodontics, orthodontics, and endodontics. However, challenges such as high costs, material limitations, and post-processing requirements...

  • Article
  • Open Access
7 Citations
4,795 Views
26 Pages

Estimating Age and Sex from Dental Panoramic Radiographs Using Neural Networks and Vision–Language Models

  • Salem Shamsul Alam,
  • Nabila Rashid,
  • Tasfia Azrin Faiza,
  • Saif Ahmed,
  • Rifat Ahmed Hassan,
  • James Dudley and
  • Taseef Hasan Farook

8 January 2025

Purpose: The purpose of this study was to compare multiple deep learning models for estimating age and sex using dental panoramic radiographs and identify the most successful deep learning models for the specified tasks. Methods: The dataset of 437 p...

  • Systematic Review
  • Open Access
7 Citations
5,903 Views
15 Pages

Use of Biosensors within the Oral Environment for Systemic Health Monitoring—A Systematic Review

  • Natalie Archer,
  • Sa’ada Ladan,
  • Henry T. Lancashire and
  • Haralampos Petridis

30 March 2024

Scientific advances in biosensor technology are leading to the potential of wearable biosensors for salivary biomarker detection. This review aims to identify the current status of intraoral biosensor technology that can be used to monitor systemic d...

  • Perspective
  • Open Access
7 Citations
5,970 Views
12 Pages

Improving Patient Experience through Meaningful Engagement: The Oral Health Patient’s Journey

  • Shamiso Chakaipa,
  • Sarah J. Prior,
  • Sue Pearson and
  • Pieter J. van Dam

8 November 2023

Healthcare organisations around the world have embraced the valuable role that patient experience plays in the improvement of health care delivery. Engaging with patients is a vital component of understanding how to deliver safe, high-quality, respec...

  • Feature Paper
  • Review
  • Open Access
7 Citations
3,906 Views
19 Pages

Photodynamic Therapy of Oral Cancer and Novel Liposomal Photosensitizers

  • Nejat Düzgüneş,
  • Jaroslaw Piskorz,
  • Paulina Skupin-Mrugalska,
  • Metin Yıldırım,
  • Melike Sessevmez and
  • Jennifer Cheung

25 June 2023

Photodynamic therapy facilitates the selective destruction of cancer tissue by utilizing a photosensitizer drug, the light near the absorbance wavelength of the drug, and oxygen. Methylene Blue, 5-aminolevulinic acid (the precursor of the photosensit...

  • Review
  • Open Access
7 Citations
7,621 Views
17 Pages

Oral Cancer Disease among the Poor: A Sri Lankan Context

  • Kalpani Senevirathna,
  • Yovanthi Anurangi Jayasinghe,
  • Shalindu Malshan Jayawickrama,
  • Hemantha Amarasinghe and
  • Ruwan Duminda Jayasinghe

4 September 2023

Oral cancer (OC) is the 16th most common cancer worldwide. In Sri Lanka, OC is the most prevalent cancer among men and the eighth among women. In most instances, OC is preceded by clinically recognizable disorders appearing on the oral mucosa, termed...

  • Feature Paper
  • Article
  • Open Access
6 Citations
5,863 Views
12 Pages

A Social Media Intervention for Promoting Oral Health Behaviors in Adolescents: A Non-Randomized Pilot Clinical Trial

  • Susana J. Calderon,
  • Carissa L. Comnick,
  • Alissa Villhauer,
  • Teresa Marshall,
  • Jan-Ulrik Dahl,
  • Jeffrey A. Banas and
  • David R. Drake

9 May 2023

Poor oral hygiene and excessive consumption of soda are among the main drivers of systemic health issues in adolescents in the United States. This non-randomized pilot clinical trial focused on the effects of a health text message system and smartpho...

  • Case Report
  • Open Access
6 Citations
4,520 Views
8 Pages

Residual Cyst Mimicking an Aggressive Neoplasm—A Life-Threatening Condition

  • Emilia Lis,
  • Michał Gontarz,
  • Tomasz Marecik,
  • Grażyna Wyszyńska-Pawelec and
  • Jakub Bargiel

26 August 2024

Odontogenic cysts are frequently encountered in clinical practice. However, residual cysts, a specific type of inflammatory odontogenic cyst, are relatively rare. These cysts may slowly expand over time, damaging surrounding soft tissues and bone, ty...

  • Review
  • Open Access
6 Citations
8,007 Views
20 Pages

3 June 2024

Digital models and three-dimensional technology in orthodontics have become an integral part of everyday clinical practice. Nevertheless, there is currently no consensus regarding in which cases a digital model is really necessary. Therefore, this sc...

  • Article
  • Open Access
6 Citations
19,248 Views
14 Pages

Effectiveness of Bioactive Toothpastes against Dentin Hypersensitivity Using Evaporative and Tactile Analyses: A Randomized Clinical Trial

  • Roberta Caroline Bruschi Alonso,
  • Letícia de Oliveira,
  • Jaqueline Alves Batista Silva,
  • Williane Bernadete Bezerra dos Santos,
  • Lúria Ribeiro de Souza Laranja Ferreira,
  • Ricardo Danil Guiraldo,
  • Fabiano Vieira Vilhena and
  • Paulo Henrique Perlatti D’Alpino

10 January 2024

The objective of this study was to investigate and compare the effectiveness of toothpastes containing bioactives to relieve dentin hypersensitivity with that of a commercial desensitizing toothpaste containing REFIX technology, associated or not wit...

  • Article
  • Open Access
6 Citations
12,500 Views
12 Pages

Evaluation of Enamel Volume Loss after Exposure to Energy Drinks

  • Karen A. Schulze,
  • Noëlle M. Santucci,
  • Bina Surti,
  • Stefan Habelitz,
  • Mouchumi Bhattacharyya and
  • Warden Noble

23 February 2024

Objectives: This study was conducted to determine the erosive potential of various commercial energy drinks (EDs), sports drinks (SDs), and sugar sweetened beverages (SSBs) and to correlate quantitative changes in tooth enamel volume loss based on th...

  • Case Report
  • Open Access
5 Citations
3,768 Views
9 Pages

Introduction to Surgical Navigation in Oral Surgery: A Case-Series

  • Giorgio Novelli,
  • Mattia Moretti,
  • Maria Costanza Meazzini,
  • Cristina Maria Angela Cassé,
  • Fabio Mazzoleni and
  • Davide Sozzi

28 March 2023

The application of surgical navigation in oral and maxillo-facial surgery has been increasing over time. In fact, computer-assisted surgery provides real-time, precise, and accurate position and guidance during surgery. The purpose of our work is to...

  • Review
  • Open Access
5 Citations
7,840 Views
13 Pages

Corticotomy-Assisted Orthodontic Treatment: A Literature Review

  • Athanasia Patatou,
  • Niovi Iacovou,
  • Paraskevi Zaxaria,
  • Michail Vasoglou and
  • Georgios Vasoglou

14 August 2023

The increased number of adults seeking orthodontic treatment has led to the need for faster results as social limitations arise with the use of fixed or even removable appliances. Corticotomy-assisted orthodontic treatment (CAOT) has been proposed as...

  • Review
  • Open Access
5 Citations
5,270 Views
24 Pages

Cultural Themes Related to Oral Health Practices, Beliefs, and Experiences in Nigeria: A Scoping Review

  • Taofeek Kolawole Aliyu,
  • Olusegun Stephen Titus,
  • Oluwabunmi Tope Bernard,
  • Omolola Titilayo Alade,
  • Adebola Oluyemisi Ehizele and
  • Moréniké Oluwátóyìn Foláyan

2 April 2025

The objective of this scoping review was to map out the cultural themes related to oral health practices, beliefs, and experiences in Nigeria; explore mythologies about oral health in Nigeria; identify the perceived cultural significance of oral heal...

  • Article
  • Open Access
5 Citations
4,261 Views
10 Pages

26 July 2024

Chelating gels may initially assist in root canal preparations to help establish a glide path. While irrigation surveys have investigated liquid chelators and gels to a minor extent, no endodontic survey has focused on EDTA gels and why clinicians us...

  • Feature Paper
  • Review
  • Open Access
5 Citations
14,752 Views
13 Pages

Periodontitis and Alzheimer’s Disease: Is There a Connection?

  • William Lundergan,
  • Kavitha Parthasarathy and
  • Navid Knight

22 January 2024

The oral health/systemic health connection has been an area of research interest that increased dramatically during the 1990s. Periodontal disease has been associated with a number of systemic conditions, including cardiovascular disease, diabetes, p...

  • Review
  • Open Access
4 Citations
7,881 Views
14 Pages

20 December 2024

Background: The adoption of digital technology in dentistry is rapidly increasing worldwide. Intraoral scanners (IOSs) have been mainly used to create 3D digital dental models but recently attracted attention as an important device for diagnosing ora...

  • Systematic Review
  • Open Access
4 Citations
3,754 Views
10 Pages

Saliva-Based Biomarkers in Oral Squamous Cell Carcinoma Using OMICS Technologies: A Systematic Review

  • Fariba Esperouz,
  • Domenico Ciavarella,
  • Andrea Santarelli,
  • Mauro Lorusso,
  • Lorenzo Lo Muzio,
  • Luigi Laino and
  • Lucio Lo Russo

2 July 2024

(1) Background: Head and neck cancer (HNC) is a major public health challenge worldwide, with oral squamous cell carcinoma (OSCC) being the predominant form. Despite advances in treatment, OSCC remains a major cause of morbidity and mortality due to...

  • Review
  • Open Access
4 Citations
11,368 Views
12 Pages

The Public Health Approach to Oral Health: A Literature Review

  • Mariel Cabrera,
  • Raman Bedi and
  • Marta Lomazzi

20 May 2024

Background: Oral health (OH) has evolved beyond dental concerns to encompass psychosocial dimensions and overall well-being. This study reviews OH strategies within a public health framework to identify key elements for effective OH promotion. Method...

  • Review
  • Open Access
4 Citations
6,226 Views
15 Pages

5 October 2023

Introduction: The provision of dental care for paediatric patients with inherited bleeding disorders (IBD) can present a challenging scenario for dentists. Although patients with a low bleeding risk can safely receive preventive procedures in the com...

  • Article
  • Open Access
4 Citations
5,218 Views
12 Pages

14 July 2023

Background: Surveys in Tanzania show that pregnant women have a significant burden of oral disease, although there is still little literature on the variation of their intraoral electrolytes. The present study investigated changes in salivary calcium...

  • Review
  • Open Access
4 Citations
7,297 Views
16 Pages

1 February 2024

Today, molar incisor hypomineralization (MIH), which affects approximately one in seven children, is defined as a hypomineralized developmental enamel defect that often impacts at least one permanent first molar and frequently affects permanent incis...

  • Case Report
  • Open Access
4 Citations
13,936 Views
9 Pages

Life-Threatening Hemorrhage from the Lingual Artery after a Genioplasty—Case Report and Review of Possible Complications Associated with Orthognathic Surgeries

  • Nikoletta Vargas,
  • Dasha Donado,
  • José S. Sifuentes-Cervantes,
  • Jaime Castro-Núñez,
  • Lidia M. Guerrero and
  • Luis Ferrer-Nuin

20 February 2023

Life-threatening hemorrhage after orthognathic surgery is rare. However, when it occurs, immediate diagnosis of the source of bleeding is imperative for successful management. The current report is the first to describe a rare life-threatening bleed...

  • Review
  • Open Access
4 Citations
4,508 Views
13 Pages

Future Prospects and Challenges in Additive Manufacturing for Complete Dentures: A Narrative Review

  • Mariya Dimitrova,
  • Angelina Vlahova,
  • Yavor Kalachev,
  • Rada Kazakova and
  • Saverio Capodiferro

26 December 2023

The utilization of computer-assisted design and computer-assisted manufacturing (CAD/CAM) techniques in the creation of complete dentures (CDs) has piqued the interest of many people. This article seeks to provide a comprehensive, critical, and objec...

  • Review
  • Open Access
4 Citations
4,374 Views
15 Pages

1 August 2025

Background: Obstructive sleep apnea (OSA) is a prevalent disorder in both pediatric and adult populations, characterized by substantial morbidity encompassing cardiovascular, neurocognitive, and metabolic impairments. Management strategies vary by ag...

  • Communication
  • Open Access
3 Citations
6,334 Views
11 Pages

Oral Toxicities in Cancer Patients, Who Receive Immunotherapy: A Case Series of 24 Patients

  • Ourania Nicolatou-Galitis,
  • Amanda Psyrri,
  • Nikolaos Tsoukalas,
  • Evangelos Galitis,
  • Helena Linardou,
  • Dimitra Galiti,
  • Ilias Athansiadis,
  • Despoina Kalapanida,
  • Evangelia Razis and
  • Konstantinos Syrigos
  • + 10 authors

20 March 2023

The oral problems of 24 cancer patients on immunotherapy between 2017–2022 and referred by their oncologists, were reported. The age range was 49–80 years, and the median was 64 years. Lung cancer was the most common disease. Three patien...

  • Systematic Review
  • Open Access
3 Citations
6,583 Views
12 Pages

21 March 2023

The main objective of this systematic review was to evaluate the microbiology of maxillary sinus infections and to determine whether an odontogenic origin of the infection can be established. The PIE question posed was the following: In patients with...

  • Article
  • Open Access
3 Citations
4,466 Views
14 Pages

Evaluating Post-Insertion Complications and Patient Satisfaction of Conventional Complete Dentures: A Retrospective Study

  • Lavanya Ajay Sharma,
  • Navodika Yaparathna,
  • Nithya Cheruka,
  • Peng Shao and
  • Menaka Abuzar

29 August 2024

Conventional complete dentures remain to be an important treatment for edentulous patients, especially those of low socioeconomic status. This study is a retrospective analysis that aims to elucidate influencing factors of post-insertion complication...

  • Article
  • Open Access
3 Citations
3,330 Views
20 Pages

22 October 2024

Objectives: Dental implants have become a cornerstone of restorative dentistry, providing a long-lasting method for tooth replacement. The degree of osseointegration has a significant effect on biomechanical stability at the bone–implant contac...

  • Review
  • Open Access
3 Citations
4,141 Views
11 Pages

Adjunctive Effects of Diode Laser in Surgical Periodontal Therapy: A Narrative Review of the Literature

  • Giuseppe D’Albis,
  • Marta Forte,
  • Maria Chiara Fioriello,
  • Alexandra Artin,
  • Anna Montaruli,
  • Adriano Di Grigoli,
  • Rada Kazakova,
  • Mariya Dimitrova and
  • Saverio Capodiferro

27 February 2025

The surgical procedures in the treatment of periodontitis generally aim to reduce pocket depth, improve teeth maintenance, and enhance long-term stability. Several approaches have been proposed over the years including different techniques, drugs, an...

  • Review
  • Open Access
3 Citations
2,714 Views
12 Pages

10 June 2025

Interim fixed dental prostheses (FDPs) play a crucial role in maintaining oral stability during the construction of final FDPs. Traditionally, interim FDPs were fabricated using conventional methods. However, advancements in digital dentistry have in...

  • Article
  • Open Access
3 Citations
3,289 Views
15 Pages

20 May 2025

Aim: This study aimed to determine the oral health profile of children with autism spectrum disorder and to analyze the impact of their oral health status on their personal quality of life and the quality of life of their families. Materials and Meth...

  • Article
  • Open Access
3 Citations
2,174 Views
14 Pages

10 May 2024

Background: The influence of medical and dental factors on jaw clicking within the South Australian population remains unexplored, and there is a lack of research on the impact of occlusal therapy on dynamic jaw movement parameters in this population...

  • Systematic Review
  • Open Access
3 Citations
4,820 Views
23 Pages

Artificial Intelligence Applications in Dentistry: A Systematic Review

  • Shareef Araidy,
  • George Batshon and
  • Roman Mirochnik

7 November 2025

Background: Artificial intelligence technologies are increasingly integrated into dental practice, offering potential improvements in diagnostic accuracy, treatment planning, and patient outcomes. However, the extent and quality of evidence supportin...

  • Conference Report
  • Open Access
3 Citations
2,529 Views
9 Pages

Oro-Dental Pharmacovigilance in the Digital Age: Promoting Knowledge, Awareness, and Practice in Italy through a Smart Combined System—A Conference at the 30th National Congress of the Italian College of University Professors of Dental Disciplines

  • Gaetano La Mantia,
  • Fortunato Buttacavoli,
  • Vera Panzarella,
  • Giuseppe Colella,
  • Annalisa Capuano,
  • Liberata Sportiello,
  • Gaspare Parrinello,
  • Ilaria Morreale,
  • Giacomo Oteri and
  • Giuseppina Campisi
  • + 7 authors

1 September 2023

Adverse drug reactions (ADRs) represent a significant threat to patients’ safety in dentistry, necessitating proactive measures for prevention and treatment. However, identifying ADRs of dental and oral interest can be challenging, and underrep...

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Oral - ISSN 2673-6373