Animal Immune Response to Parasitic Infections

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 1519

Special Issue Editors


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Guest Editor
1. Instituto Politécnico de Viseu, Escola Superior Agrária de Viseu, Viseu, Portugal
2. Global Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, Lisboa, Portugal
3. CERNAS-IPV Research Centre, Instituto Politécnico de Viseu, Viseu, Portugal
Interests: canine leishmaniasis; parasite immunology; cellular immunology; molecular immunology; innate immune response; parasite–host interaction; neutrophils; macrophages
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Global Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, Lisboa, Portugal
Interests: immunology; parasitology; leishmania; molecular biology; cellular biology; vaccine; new drugs
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Global Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, Lisboa, Portugal
Interests: immunology; host-parasite interaction; parasitology; extracellular vesicles; 3D cell models; cell biology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Parasitic diseases in domestic and wild animals are a major cause of concern due to their interference with animal welfare and health, which can also lead to significant economic losses. Although the establishment of a parasitic infection depends on several factors related to the parasite, the environment and the host, the immune competence an animal often determines the outcome of the infection. Unraveling the complexity of the host’s immune responses at different stages of the infection will contribute to the development of more effective diagnostics and innovative control strategies. The application of novel and sophisticated approaches, such as genomics, reverse genetic analysis, proteomics, and bioinformatics techniques, can reveal the complexity of the immune response induced by protozoa, trematodes, cestodes, nematodes, and arthropods. Thus, we cordially invite authors to submit original research or review articles pertaining to the immunology of parasitic infection in animals.

Dr. Maria Pereira
Dr. Gabriela Santos Gomes
Dr. Armanda Rodrigues
Guest Editors

Manuscript Submission Information

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Keywords

  • domestic animals
  • wild animals
  • host–parasite interaction
  • immunology of zoonosis
  • parasitic immunology
  • anti-parasitic drugs
  • anti-parasitic vaccines
  • immunomodulators for parasitic infections

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Published Papers (1 paper)

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Review

17 pages, 1228 KiB  
Review
Techniques, Databases and Software Used for Studying Polar Metabolites and Lipids of Gastrointestinal Parasites
by Phurpa Wangchuk and Karma Yeshi
Animals 2024, 14(18), 2671; https://doi.org/10.3390/ani14182671 - 13 Sep 2024
Viewed by 1052
Abstract
Gastrointestinal parasites (GIPs) are organisms known to have coevolved for millennia with their mammalian hosts. These parasites produce small molecules, peptides, and proteins to evade or fight their hosts’ immune systems and also to protect their host for their own survival/coexistence. The small [...] Read more.
Gastrointestinal parasites (GIPs) are organisms known to have coevolved for millennia with their mammalian hosts. These parasites produce small molecules, peptides, and proteins to evade or fight their hosts’ immune systems and also to protect their host for their own survival/coexistence. The small molecules include polar compounds, amino acids, lipids, and carbohydrates. Metabolomics and lipidomics are emerging fields of research that have recently been applied to study helminth infections, host–parasite interactions and biochemicals of GIPs. This review comprehensively discusses metabolomics and lipidomics studies of the small molecules of GIPs, providing insights into the available tools and techniques, databases, and analytical software. Most metabolomics and lipidomics investigations employed LC-MS, MS or MS/MS, NMR, or a combination thereof. Recent advancements in artificial intelligence (AI)-assisted software tools and databases have propelled parasitomics forward, offering new avenues to explore host–parasite interactions, immunomodulation, and the intricacies of parasitism. As our understanding of AI technologies and their utilisation continue to expand, it promises to unveil novel perspectives and enrich the knowledge of these complex host–parasite relationships. Full article
(This article belongs to the Special Issue Animal Immune Response to Parasitic Infections)
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