Gastrointestinal Tract Health in Pigs – 2nd Edition

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Pigs".

Deadline for manuscript submissions: 4 November 2024 | Viewed by 1079

Special Issue Editors


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Guest Editor
Department of Animal Production, University of Murcia, Avenida Teniente Flomesta 5, 30860 Murcia, Spain
Interests: pigs; intestinal disease; intestinal integrity; intestinal immune system; vaccine; nutrition additives; piglet management
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Guest Editor
Escola de Vetérinaria, Universidade Federal de Goiás, Goiánia 74001-970, Brazil
Interests: intestinal disease; nutrition modelization; immune system activation; intestinal integrity; vaccines
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Intestinal health has become a major concern for producers and swine practitioners. In recent decades, we have continuously lost the tools required to maintain intestinal health in piglets and pigs, which has resulted in worse health status and loss of performance in pig production. The lack of vaccines, the ban on antimicrobials or zinc oxide usage, for example, have greatly contributed to this situation. Therefore, it is critical to create of knowledge to improve intestinal integrity and digestive health and to help producers to maintain the health of animals and the profitability of agribusiness related to swine production. Intestinal integrity, nutrition (formulation, modelization), microbiome, nutritional additives, probiotics and prebiotics, and vaccines are some of the topics that will be addressed in this Special Issue of Animals.

The aim of the present Special Issue is to compile some of the most recent advances in intestinal integrity and digestive health into one publication.

Considering the success of our previous Special Issue, "Gastrointestinal Tract Health in Pigs", we are pleased to launch “Gastrointestinal Tract Health in Pigs – 2nd Edition”. We welcome the submission of research articles and literature reviews.

Prof. Dr. Guillermo Ramis
Dr. Livia Mendonça Pascoal
Guest Editors

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Keywords

  • intestinal integrity
  • porcine enteric disease syndrome
  • tight junctions
  • vaccine
  • microbiome
  • nutrition

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Published Papers (1 paper)

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Research

14 pages, 2911 KiB  
Article
Effects of Luteolin in an In Vitro Model of Porcine Intestinal Infections
by Dóra Kovács, Nikolett Palkovicsné Pézsa, Alma Virág Móritz, Ákos Jerzsele and Orsolya Farkas
Animals 2024, 14(13), 1952; https://doi.org/10.3390/ani14131952 - 2 Jul 2024
Cited by 1 | Viewed by 682
Abstract
Intestinal infections caused by Escherichia coli and Salmonella enterica pose a huge economic burden on the swine industry that is exacerbated by the development of antimicrobial resistance in these pathogens, thus raising the need for alternative prevention and treatment methods. Our aim was [...] Read more.
Intestinal infections caused by Escherichia coli and Salmonella enterica pose a huge economic burden on the swine industry that is exacerbated by the development of antimicrobial resistance in these pathogens, thus raising the need for alternative prevention and treatment methods. Our aim was to test the beneficial effects of the flavonoid luteolin in an in vitro model of porcine intestinal infections. We infected the porcine intestinal epithelial cell line IPEC-J2 with E. coli and S. enterica subsp. enterica serovar Typhimurium (106 CFU/mL) with or without previous, concurrent, or subsequent treatment with luteolin (25 or 50 µg/mL), and measured the changes in the reactive oxygen species and interleukin-6 and -8 levels of cells. We also tested the ability of luteolin to inhibit the adhesion of bacteria to the cell layer, and to counteract the barrier integrity damage caused by the pathogens. Luteolin was able to alleviate oxidative stress, inflammation, and barrier integrity damage, but it could not inhibit the adhesion of bacteria to IPEC-J2 cells. Luteolin is a promising candidate to be used in intestinal infections of pigs, however, further studies are needed to confirm its efficacy. The use of luteolin in the future could ultimately lead to a reduced need for antibiotics in pig production. Full article
(This article belongs to the Special Issue Gastrointestinal Tract Health in Pigs – 2nd Edition)
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