Deslorelin Implant: An Ethical and Medical Option in Small Animal Medicine
A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".
Deadline for manuscript submissions: closed (5 December 2022) | Viewed by 26019
Special Issue Editors
Interests: animal reproduction and obstetrics; male and female fertility; canine prostatic disorders; ultrasound of the male and female genital tract; reproductive surgery
Special Issue Information
Dear Colleagues,
The use of deslorelin, a GnRH agonist, in the form of slow-release implants, represents a pivotal interest in small animal theriogenology. Many ongoing studies seek to deepen its use in reproductive control while developing new applications in several fields of veterinary medicine.
The topic of contraception and controlling unwanted reproduction has been widely discussed in the last decades. For a long time, surgical castration was considered the only alternative to achieve contraception in small animals, but many concerns about the risks and benefits of this procedure progressively arose. The ethical approach to castration became of foundational importance. The scientific community actively looked for alternative contraceptive medications. For these reasons, the first and main use of deslorelin in clinical practice was the control of male fertility and reproductive potential.
Progressively, further applications were discovered.
Nowadays, deslorelin is used in several fields of small animal medicine with different indications: medical contraception and delay of puberty in male dogs; part of medical protocols to treat benign prostatic hyperplasia in male dogs; control of testosterone-linked unwanted behaviors in male dogs and tomcats; medical castration of tomcats; estrous induction and delay of puberty in bitches; treatment of post-spaying urinary incontinence and spay-induced coat changes in bitches; treatment of some cutaneous disorders, such as alopecia X, in dogs; estrous suppression and delay of puberty in queens; contraception and treatment of adrenal disorders in ferrets; management of reproduction in wild carnivores such as lions and cheetahs; and control of reproduction, hormonal-related diseases and behaviors in exotic species, such as avian species, small mammals and reptiles. Moreover, studies on the molecular mode of action of surgical and medical castration, especially the differences regarding LH secretions and their consequences, are ongoing.
High-quality original research papers and reviews concerning the wide variety of applications and uses of deslorelin in dogs, cats and exotic species are very welcome in this Special Issue that aims to share recent findings related to animal reproduction as well as any other branch of veterinary medicine
Dr. Salvatore Alonge
Dr. Monica Melandri
Guest Editors
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Keywords
- benign prostatic hyperplasia
- castration
- cat
- deslorelin
- dog
- exotics
- ferret
- FSH
- GnRH-agonists
- LH
- puberty
- tomcat
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