Molecular Characterization and Antimicrobial Resistance of Pathogens Isolated from Animals

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotics in Animal Health".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 964

Special Issue Editor


E-Mail Website
Guest Editor
1. Microbiology and Antibiotic Resistance Team (MicroART), Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal
2. Biochemistry and Molecular Biology, University of La Rioja, Logrono, Spain
3. Laboratory Associated for Green Chemistry (LAQV-REQUIMTE), New University of Lisbon, Monte da Caparica, Portugal
Interests: antibiotic resistance; genetics; Enterobacteriaceae; microbiology; One Health; Maldi-TOF

Special Issue Information

Dear Colleagues,

Antibiotic resistance is considered a significant public health concern, caused by the use, overuse, and misuse of these drugs in clinic prescription and veterinary medicine. According to some estimations, around 700,000 human deaths every year worldwide are due to the failure of antibiotic treatments for bacterial infections. It has been predicted that this will increase to 10 million people/year by 2050, which represents more than the current mortality associated with different cancers. In recent decades, various studies have reported this situation in animals (including wildlife and pets), humans, and the environment, focusing on a One Health approach.

With this Special Issue, we are looking to gather together manuscripts related to antimicrobial resistance among animals, and studies performed in any part of the world are welcome. The isolation of pathogens harboring novel mutations and mobile genetic elements associated with extended-spectrum beta-lactams, carbapenems, methicillin, and vancomycin are strongly encouraged.

Prof. Dr. Isabel Carvalho
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antibiotic resistance
  • molecular biology
  • microbiology
  • genomics
  • multi-drug resistance
  • One Health
  • animals

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

19 pages, 7385 KiB  
Article
Genomic Profiling of Antimicrobial Resistance Genes in Clinical Salmonella Isolates from Cattle in the Texas Panhandle, USA
by Max Chung, Ethan Dudley, Hatem Kittana, Alexis C. Thompson, Matthew Scott, Keri Norman and Robert Valeris-Chacin
Antibiotics 2024, 13(9), 843; https://doi.org/10.3390/antibiotics13090843 - 4 Sep 2024
Viewed by 713
Abstract
Rising antimicrobial resistance (AMR) in Salmonella serotypes host-adapted to cattle is of increasing concern to the beef and dairy industry. The bulk of the existing literature focuses on AMR post-slaughter. In comparison, the understanding of AMR in Salmonella among pre-harvest cattle is still [...] Read more.
Rising antimicrobial resistance (AMR) in Salmonella serotypes host-adapted to cattle is of increasing concern to the beef and dairy industry. The bulk of the existing literature focuses on AMR post-slaughter. In comparison, the understanding of AMR in Salmonella among pre-harvest cattle is still limited, particularly in Texas, which ranks top five in beef and dairy exports in the United States; inherently, the health of Texas cattle has nationwide implications for the health of the United States beef and dairy industry. In this study, long-read whole genome sequencing and bioinformatic methods were utilized to analyze antimicrobial resistance genes (ARGs) in 98 isolates from beef and dairy cattle in the Texas Panhandle. Fisher exact tests and elastic net models accounting for population structure were used to infer associations between genomic ARG profiles and antimicrobial phenotypic profiles and metadata. Gene mapping was also performed to assess the role of mobile genetic elements in harboring ARGs. Antimicrobial resistance genes were found to be statistically different between the type of cattle operation and Salmonella serotypes. Beef operations were statistically significantly associated with more ARGs compared to dairy operations. Salmonella Heidelberg, followed by Salmonella Dublin isolates, were associated with the most ARGs. Additionally, specific classes of ARGs were only present within mobile genetic elements. Full article
Show Figures

Figure 1

Back to TopTop