Bacterial Infections and Global Health: The Escalating Threat of Antibiotic Resistance

Dear Colleagues,

Bacterial infections, especially those induced by multidrug-resistant pathogens, have become a significant global health concern. Indeed, antimicrobial resistance (AMR) is one of the top threats to global public health and development. It is estimated that bacterial AMR was directly responsible for 1.27 million global deaths in 2019 and contributed to a further 4.95 million deaths.

Moreover, there are estimations that by 2050 the mortality rate attributed to AMR infections will reach 4.73 million (Asia), 4.15 million (Africa), 0.39 million (Europe), 0.392 million (Latin America), 0.317 million (North America), and 0.022 million (Oceania) in different areas of the world.

Additionally, there is more concern about this in developing countries, due to the misuse and overuse of antimicrobials in humans, animals, and plants.

This leads to difficult situations, such as a limited choice between treatments for physicians, increased lengths of hospitalization and expenses, and increased morbidity and mortality.

This Special Issue aims to focus on particular topics and will prioritize those that address AMR in human health with the aim of preventing all infections; stewardship and the inappropriate use of antimicrobials; the surveillance of AMR and antimicrobial consumption/use; universal access to quality diagnoses and appropriate treatments for infections; strategic information and innovations; and research and development for the creation of novel vaccines, diagnostics, and medicines.

Prof. Dr. Nicola Petrosillo
Dr. Guido Granata
Guest Editors

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