Special Issues

Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria, 2nd Edition submission deadline 31 Oct 2026 | Viewed by 295 | Submission Open
Keywords: antimicrobial resistance mechanism; mobile genetic element; horizontal gene transfer; resistome; evolution; molecular phylogenetics; genomics; bioinformatics analysis; next-generation sequencing
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Antimicrobial Treatment Challenges in Gastroenterology and Malignancy-Associated Infections: Current Trends, Debates and Future Perspectives
edited by and Péter Birinyi
submission deadline 31 Oct 2026 | Viewed by 260 | Submission Open
Keywords: gastroenterology; oncology; antibiotic resistance; antimicrobial treatment
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Combating Biofilm-Related Infections: Novel Therapeutics and Strategies, 2nd Edition
edited by Veronica Panichi and
submission deadline 31 Oct 2026 | Viewed by 248 | Submission Open
Keywords: biofilm-related infections; anti-biofilm agents; antimicrobial tolerance; advanced biofilm studies
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Genomic Analysis and Molecular Characterization of Antimicrobial-Resistant Bacteria
edited by
submission deadline 31 Oct 2026 | Viewed by 234 | Submission Open
Keywords: carbapenem-resistant Gram-negative bacteria; methicillin-resistant Staphylococcus aureus; next-generation sequencing; digital PCR; real-time PCR; antimicrobial resistance genes; plasmids
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Antibiotic Use and Antibiotic Residues in Food Production
edited by Ismail Murat Palabiyik and
submission deadline 31 Oct 2026 | Viewed by 217 | Submission Open
Keywords: antibiotic use in animals; veterinary drug legislation; food safety; antimicrobial resistance (AMR); risk assessment; one-health approach; sample preparation techniques; antibiotic residue analysis in food
Multidrug-Resistant Gram-Negative Bacteria Infections: Current Epidemiology, Prognosis and Treatment Options, 2nd Edition
edited by Novella Carannante
submission deadline 31 Oct 2026 | Viewed by 214 | Submission Open
Keywords: multidrug-resistant gram-negative bacteria; epidemiology and prognosis; antibiotic treatment options; antimicrobial resistance; infection control and antibiotic use
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Invasive Fungal Infections: Pathogenesis, Resistance, and Treatment Advances
edited by
submission deadline 31 Oct 2026 | Viewed by 201 | Submission Open
Keywords: invasive fungal infections; antifungal resistance; candida auris; aspergillus fumigatus; emerging fungal pathogens; fungal pathogenesis; host–pathogen interactions; biofilms; rapid molecular diagnostics; genomic surveillance; novel antifungal agents; combination therapy; immunotherapy; one health; environmental azole resistance
(This special issue belongs to the Section Fungi and Their Metabolites)
Antibiotics and Gut Microbiota: Mechanisms and Biological Consequences of Antibiotic Exposure
edited by
submission deadline 31 Oct 2026 | Viewed by 166 | Submission Open
Keywords: antibiotics; gut microbiota; dysbiosis; gut microbial ecology; antibiotic–microbiome interactions; antibiotic resistance genes; gut microbial resilience
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Epidemiology and Genomics of Antimicrobial Resistance of Difficult-to-Treat Pathogens, 2nd Edition
edited by Simone Ambretti
submission deadline 31 Oct 2026 | Viewed by 135 | Submission Open
Keywords: antimicrobial resistance; difficult-to-treat pathogens; epidemiology; genomics; MRSA; VRE; ESBL; CRE; CRAB; MDR pseudomonas aeruginosa
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Polymicrobial Biofilms and Antimicrobial Resistance Across Human, Animal, and Environmental Health
edited by
submission deadline 10 Nov 2026 | Viewed by 177 | Submission Open
Keywords: antimicrobial resistance; polymicrobial biofilms; interspecies interactions; biofilm-associated infections; antibiotic tolerance; One Health; ESKAPE pathogens; antimicrobial stewardship
(This special issue belongs to the Section Antibiofilm Strategies)
Optimizing Antimicrobial Use: Antimicrobial Stewardship and Surveillance, 2nd Edition
edited by
submission deadline 15 Nov 2026 | 1 articles | Viewed by 1333 | Submission Open
Keywords: antimicrobial stewardship; antimicrobial cycling; antimicrobial resistance; decision support; antibiotic optimization; antibiotic therapy
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Optimizing Antibiotic Use and Consumption: Integrating Surveillance, Policy and Practice submission deadline 15 Nov 2026 | 1 articles | Viewed by 783 | Submission Open
Keywords: infectious disease; antimicrobial stewardship; antibiotic use; antimicrobial consumption; point prevalence survey
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
The Global Antibiotic Imperative: Bridging Access, Stewardship, and Innovation
edited by and Aslihan Kurt Kizildogan
submission deadline 15 Nov 2026 | Viewed by 88 | Submission Open
Keywords: antimicrobial resistance (AMR); antibiotic stewardship (AMS); global health equity; One Health approach; drug discovery pipeline; point-of-care diagnostics; sustainable access; LMIC health systems; public–private partnerships; pathogen surveillance.
(This special issue belongs to the Section The Global Need for Effective Antibiotics)
Challenges and Emerging Strategies to Tackle the Global Burden of Antimicrobial Resistance submission deadline 30 Nov 2026 | 5 articles | Viewed by 23369 | Submission Open
Keywords: antimicrobial resistance (AMR); global burden of AMR; AMR in the context of public and global health; diagnostic and treatment of AMR; new approaches to AMR surveillance; antibiotic stewardship; local and global policy initiatives on AMR; prevention of AMR
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Emerging Challenges in Food Safety: Addressing Antimicrobial Resistance, Virulence Factors, and Biofilm Formation in Food-Borne Pathogens
edited by , Marian Mihaiu and
submission deadline 30 Nov 2026 | 4 articles | Viewed by 13766 | Submission Open
Keywords: antimicrobial resistance; food-borne pathogens; food safety; virulence factors; biofilm formation; resistance genes; food production; public health; molecular epidemiology; infection control
Optimizing Antimicrobial Therapy in NICU Settings: Strategies and Implications submission deadline 30 Nov 2026 | 3 articles | Viewed by 8765 | Submission Open
Keywords: neonatal ICU; antimicrobial stewardship; antimicrobial resistance; neonatal sepsis; biomarkers
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Antimicrobial Resistance and One Health: New Solutions for an Old Problem? submission deadline 30 Nov 2026 | 3 articles | Viewed by 7560 | Submission Open
Keywords: antimicrobial resistance; one health; global health; surveillance; primary porduction; food safety; environment health; nosocomial infections
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Genomic Surveillance of Antimicrobial Resistance (AMR)
edited by Linzy Elton
submission deadline 30 Nov 2026 | 7 articles | Viewed by 7360 | Submission Open
Keywords: antimicrobial resistance; sequencing; genomics; surveillance; mobile genetic elements; multi-drug-resistant organisms; One Health; metagenomics; whole-genome sequencing
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Novel Antimicrobial Strategies to Combat Multidrug-Resistant (MDR) Gram-Negative Bacteria, 2nd Edition
edited by
submission deadline 30 Nov 2026 | 3 articles | Viewed by 4876 | Submission Open
Keywords: gram negative; antibiotic resistance; antiseptic resistance; multidrug resistant; extensively drug resistant; pandrug resistant; MDR; XDR; PDR; efflux pumps; mechanisms of resistance; beta-lactamase; outer membrane
Structure and Function of Antimicrobial Peptides
edited by Daniel Balleza and
submission deadline 30 Nov 2026 | 2 articles | Viewed by 4110 | Submission Open
Keywords: antimicrobial peptides; natural peptides; lipidomics; synergistic action; bioactivity mechanisms; structure reconfiguration
(This special issue belongs to the Section Antimicrobial Peptides)
Optimizing Empirical Antibiotic Therapy in Critical Care: Innovations in Diagnostics, Digitalization, and Stewardship submission deadline 30 Nov 2026 | 2 articles | Viewed by 2396 | Submission Open
Keywords: critical care; intensive care units; empirical antibiotic therapy; antimicrobial stewardship; rapid molecular diagnostics; digital health; artificial intelligence; antimicrobial resistance; targeted therapy; polypharmacy reduction; novel antibiotics; sepsis management
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Rethinking Tuberculosis Treatment: Integrating Antimicrobial Compounds, Host Responses, and Comorbidities submission deadline 30 Nov 2026 | 2 articles | Viewed by 2269 | Submission Open
Keywords: tuberculosis; Mycobacterium tuberculosis; anti-tubercular drugs; antimicrobial resistance; host-directed therapy; TB vaccines; TB comorbidities; translational therapeutics
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Advances in Streptococcus spp. Research: Pathogenicity, Resistance, and Clinical Implications submission deadline 30 Nov 2026 | 1 articles | Viewed by 2160 | Submission Open
Keywords: Streptococcus; Corynebacterium; epidemiology; virulence; antimicrobial resistance
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Synthetic Biology Brings New Opportunity for Antibiotics Discovery, 2nd Edition
edited by , , Zixin Deng, Lixin Zhang and
submission deadline 30 Nov 2026 | 1 articles | Viewed by 1752 | Submission Open
Keywords: bioactive natural products; biosynthesis; microbial cell factory; synthetic biology; metabolic engineering; advanced biotechnology; antibiotics
(This special issue belongs to the Section Plant-Derived Antibiotics)
Virulence, Antimicrobial Resistance and Biofilm Production in Veterinary, Zoonotic and Food-Related Pathogens, 2nd Edition
edited by Óscar Mencía-Ares, Paula Fernández-Gómez and
submission deadline 30 Nov 2026 | 1 articles | Viewed by 1738 | Submission Open
Keywords: animal health; antimicrobial resistance; biofilm; food-borne pathogens; microbiology; pathogenicity; public health; veterinary pathogens; virulence; zoonosis
(This special issue belongs to the Section Antibiotics in Animal Health)
Antibiotic Surveillance and Related Infections in Intensive Care Unit
edited by Lucia Brescini
submission deadline 30 Nov 2026 | 2 articles | Viewed by 985 | Submission Open
Keywords: ICUs; antibiotic surveillance; multidrug resistance; bacterial infections; antimicrobial stewardship; compromised patients
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Detection of Bacteria and Antimicrobial Resistance in Clinical Infections
edited by , Juana Mercedes Del Valle-Mendoza and
submission deadline 30 Nov 2026 | 1 articles | Viewed by 910 | Submission Open
Keywords: bacterial detection; clinical microbiology; antimicrobial resistance (AMR); multidrug-resistant bacteria (MDR); rapid diagnostics; molecular diagnostics; whole-genome sequencing (WGS); antimicrobial susceptibility testing (AST); carbapenem resistance; resistance genes; nosocomial infections; One Health
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Feature Reviews in Pharmacokinetics and Pharmacodynamics of Drugs 2026
edited by
submission deadline 30 Nov 2026 | 1 articles | Viewed by 719 | Submission Open
Keywords: pharmacokinetics; pharmacodynamics; antibiotics; antimicrobial resistance; antimicrobial stewardship; therapeutic drug monitoring; population pharmacokinetic analysis; model-informed precision dosing; physiologically based pharmacokinetic modeling; dose optimization
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)
Therapeutic Strategies for Complicated Hospital-Acquired Infections in the Era of Antimicrobial Resistance submission deadline 30 Nov 2026 | 1 articles | Viewed by 664 | Submission Open
Keywords: hospital-acquired infections; antimicrobial resistance; multidrug-resistant pathogens; novel antibiotics; antimicrobial stewardship; invasive fungal infections
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Drug Discovery in the Fight Against Bacterial Infections submission deadline 30 Nov 2026 | Viewed by 564 | Submission Open
Keywords: drug discovery against gram-positive bacteria; drug discovery against gram-negative bacteria; drug discovery against fungi; drug discovery against biofilms
Bacteriophage- and Protein-Based Strategies to Fight Against Bacterial Infections
edited by Joseph Atia Ayariga
submission deadline 30 Nov 2026 | 1 articles | Viewed by 422 | Submission Open
Keywords: bacteriophage therapy; antimicrobial resistance; phage-derived proteins; endolysins; antimicrobial peptides; protein engineering
(This special issue belongs to the Section Bacteriophages)
Feature Reviews in Genetic and Biochemical Studies of Antibiotic Activity and Drug Resistance 2026 submission deadline 30 Nov 2026 | Viewed by 381 | Submission Open
Keywords: multidrug resistance; persistence mechanisms; stress response pathways; drug–target interactions; antibiotic mechanism of action; antibiotic discovery
(This special issue belongs to the Section Genetic and Biochemical Studies of Antibiotic Activity and Resistance)
Phage Therapy in Clinical Practice: Combating Antibiotic Resistance
edited by
submission deadline 30 Nov 2026 | Viewed by 240 | Submission Open
Keywords: phage therapy; multidrug resistance; biofilm; infection; bacteriophages; MDR pathogens
(This special issue belongs to the Section Bacteriophages)
Challenges to ‘One Health’: Zoonotic and Antimicrobial-Resistant Diseases
edited by and Shan Wang
submission deadline 30 Nov 2026 | Viewed by 220 | Submission Open
Keywords: zoonotic diseases; antimicrobial resistance (AMR); One Health; zoonotic pathogens; whole-genome sequencing (WGS); foodborne pathogens; human–animal interface; AMR transmission; multi-omics; artificial intelligence; surveillance systems; wastewater and environmental contamination; public health microbiology
Clinical Guidelines and Real Practice of Antimicrobial Pharmacotherapy, 2nd Edition
edited by
submission deadline 30 Nov 2026 | Viewed by 215 | Submission Open
Keywords: adverse drug reaction; patient adherence; antimicrobial resistance; clinical guidelines; clinical settings; regional factors; pharmacotherapy
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Computational Approaches in Discovery and Design of Antimicrobial Peptides—3rd Edition submission deadline 30 Nov 2026 | Viewed by 202 | Submission Open
Keywords: search/design of AMPs; bioinformatics; machine-learning; artificial intelligence; biodiscovery; computational analyses/tools; omics sciences; similarity networks; in vitro evaluations
(This special issue belongs to the Section Antimicrobial Peptides)
Safer Hospitals: Hygiene, Decontamination, and Antimicrobial Stewardship for HAI Control submission deadline 30 Nov 2026 | Viewed by 191 | Submission Open
Keywords: hospital hygiene; healthcare-associated infections; infection prevention and control; environmental monitoring; disinfection; decontamination; antimicrobial stewardship; antimicrobial resistance; biofilms; behavioral interventions
Mining Actinomycetes for New Antimicrobial Agents
edited by
submission deadline 30 Nov 2026 | Viewed by 190 | Submission Open
Keywords: actinomycetes; antimicrobial agents; antimicrobial discovery; natural products; secondary metabolites; drug discovery; genome mining; biosynthetic gene clusters; antimicrobial resistance; OMICS approaches
From Farm to Fork: Integrating One Health Approaches to Monitor and Mitigate Antimicrobial Resistance
edited by
submission deadline 30 Nov 2026 | Viewed by 168 | Submission Open
Keywords: One Health; farm to fork; antimicrobial use; antimicrobial resistance; monitoring; food safety
Fibrous and Composite Materials as Antimicrobial Drug Delivery Systems submission deadline 30 Nov 2026 | Viewed by 165 | Submission Open
Keywords: antimicrobial biomaterials; drug delivery systems; electrospinning; fibrous scaffolds; nanomaterials; wound healing; infection-responsive materials; controlled release; medical textiles; composite materials
(This special issue belongs to the Section Novel Antimicrobial Agents)
Natural Antimicrobial Compounds: From Phytochemicals to Novel Therapeutic Candidates
edited by Sevgi Kolaylı
submission deadline 30 Nov 2026 | Viewed by 161 | Submission Open
Keywords: antimicrobial resistance; natural products; bee products; bioactive compounds; drug-resistant pathogens
(This special issue belongs to the Section Plant-Derived Antibiotics)
Presence, Dissemination and Removal of Antibiotics Resistance in Water Environments
edited by Denga Ramutshatsha-Makhwedzha and
submission deadline 30 Nov 2026 | Viewed by 158 | Submission Open
Keywords: antibiotic resistance; wastewater; water treatment technologies; pharmaceticals; resistant bacteria; material synthesis; nanotechnology; biosorbents; nanocomposite
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Antimicrobial Resistance from the One Health Perspective
edited by Samuel Paulo Cibulski
submission deadline 30 Nov 2026 | Viewed by 156 | Submission Open
Keywords: antimicrobial resistance; One Health; multidrug-resistant pathogens; environmental resistome; horizontal gene transfer; novel antimicrobials; bioprospecting; antimicrobial stewardship; genomics; public health
Natural Antimicrobials from Discovery to Application: Challenges and Opportunities submission deadline 30 Nov 2026 | Viewed by 148 | Submission Open
Keywords: natural antimicrobials; biocides; antibiotic alternatives; antimicrobial resistance; biofilms; applied microbiology; microbial ecology; sustainable antimicrobials; cultural heritage biodeterioration; one health
(This special issue belongs to the Section Plant-Derived Antibiotics)
Preventing Antimicrobial Resistance in Hospitals: Infection Control and Antibiotic Use—2nd Edition
edited by
submission deadline 30 Nov 2026 | Viewed by 143 | Submission Open
Keywords: clinical antibiotic use; hospital infection control; healthcare-associated infections; resistance mitigation strategies; alternative therapies; antibiotic stewardship; molecular mechanisms of AMR; new therapeutic combinations of antibiotics; antimicrobial synergy
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
A Themed Issue in Honor of Professor David A. Stevens—Outstanding Contributions in the Fields of Epidemiology and Therapy of Fungal Infections submission deadline 30 Nov 2026 | Viewed by 77 | Submission Open
Keywords: sporotrichosis; Sporothrix brasiliensis; new antifungal treatment; endemic mycoses
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Identification, Surveillance and Interventional Strategies for Antimicrobial Resistance submission deadline 30 Nov 2026 | Viewed by 68 | Submission Open
Keywords: antimicrobial resistance; surveillance; genomic epidemiology; One Health; antimicrobial stewardship; resistance mechanisms; infection control; alternative therapies; predictive modeling
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Strategies to Combat Antibiotic Resistance and Microbial Biofilms, 2nd Edition submission deadline 30 Nov 2026 | Viewed by 60 | Submission Open
Keywords: antibiotic resistance; biofilms; nanotechnology; medicinal plants; synthetic
(This special issue belongs to the Section Novel Antimicrobial Agents)
Epidemiology of Zoonotic Pathogens in Ruminants: A One Health Perspective
edited by and
submission deadline 30 Nov 2026 | Viewed by 28 | Submission Open
Keywords: one health; epidemiology; zoonoses; ruminant infections
(This special issue belongs to the Section Antibiotics in Animal Health)
Advances in Infective Endocarditis Research: From Bench to Bedside
edited by Joya-Rita Hindy
submission deadline 15 Dec 2026 | 4 articles | Viewed by 7246 | Submission Open
Keywords: infective endocarditis; prosthetic valve endocarditis; cardiac implantable electronic devices; recurrent infective endocarditis; valvular heart disease; cardiac surgery; molecular diagnostics; innovative drug delivery; antimicrobial resistance; suppressive therapy
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
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