Oxidative Stress and Immune Regulation in Respiratory Diseases
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 1985
Special Issue Editor
2. Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain
Interests: respiratory diseases; COPD; asthma; pulmonary fibrosis; oxidative stress; redox balance; mitochondrial dysfunction; immune system; inflammation; pulmonary hypertension; heart failure
Special Issue Information
Dear Colleagues,
Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD), asthma, and idiopathic pulmonary fibrosis (IPF), are characterized by increased oxidative stress, which contributes to the disease process. Exposure to pollutants, smoking, and poor diets are major contributors to oxidative stress. On the other hand, the interplay between oxidative stress and immune regulation plays a central role in the pathophysiology, exacerbation, and progression of these chronic respiratory diseases. Interventions aimed at optimizing these factors can support better disease outcomes; therefore, research aimed at uncovering the mechanisms that trigger oxidative stress and immune dysregulation offers valuable insights into the underlying processes of such diseases. Additionally, lungs cells contain various enzymatic and non-enzymatic antioxidant responses that counteract these pro-oxidant effects or generations. An imbalance between pro-oxidants and antioxidants causes oxidative stress, which is known to be associated with the pathogenesis of different chronic respiratory diseases. This Special Issue of Antioxidants aims to publish articles that address the pathophysiological mechanisms of various stimuli that lead to oxidative stress and examine all aspects of airway inflammation in chronic respiratory diseases. This knowledge can drive the development of new therapeutic targets and strategies. Original research papers detailing recent discoveries in lung redox biology and inflammation are welcome, along with reviews from experts in this field.
Prof. Dr. María José Calzada
Guest Editor
Manuscript Submission Information
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Keywords
- chronic respiratory diseases
- oxidative stress
- immune regulation
- airway inflammation
- mitochondrial dysfunction
- pulmonary hypertension
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