Oxidative Stress Responses to Freshwater and Marine Toxins: From Molecular Mechanisms to Ecological Impacts

A special issue of Antioxidants (ISSN 2076-3921).

Deadline for manuscript submissions: 14 February 2025 | Viewed by 1479

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Laboratory of Marine Toxins, Physiology and Biophysics Program, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago 8380000, Chile
Interests: ecotoxicology; marine biology; marine toxins; oxidative stress
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Special Issue Information

Dear Colleagues,

Acute or chronic exposure to environmental pollutants, such as blooms associated with the production of marine toxins, may produce a number of alterations within aquatic organisms. Although they can tolerate a certain number of short-term pollutant-induced biological disturbances, long-term exposure can deplete repair and defense mechanisms, causing a negative impact on cell organization, known as oxidative stress.

Oxidative stress is an important component of the biological responses of freshwater and marine organisms when exposed to a wide variety of environmental stressors on different scales of time and space. Therefore, oxidative stress is produced when the rate of production of reactive oxygen species (ROS) exceeds the rate of elimination produced by endogenous antioxidant molecules. Thus, this imbalance leads to the production and accumulation of ROS, causing damage to lipids, proteins, and the DNA of cells of aquatic organisms. The damage can be determined depending on the species, age, organ, type of exposure, type of material, duration of the dose, and external environmental factors.

We invite you to submit your latest research findings or a review article to this Special Issue, entitled “Oxidative Stress Responses to Freshwater and Marine Toxins: From Molecular Mechanisms to Ecological Impacts”.

We look forward to your contribution.

Dr. Carlos García
Guest Editor

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Keywords

  • ecotoxicology

  • marine biology
  • oxidative stress
  • marine toxins
  • bivalves
  • gastropods
  • reactive oxygen species
  • antioxidant system
  • superoxide dismutase
  • harmful effects
  • cyanotoxins
  • cyanobacteria
  • human and animal health
  • molecular mechanisms
  • bioaccumulation
  • invertebrates
  • vertebrates

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Published Papers (1 paper)

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Review

17 pages, 1822 KiB  
Review
Domoic Acid: A Review of Its Cytogenotoxicity Within the One Health Approach
by Goran Gajski, Marko Gerić, Ana Baričević and Mirta Smodlaka Tanković
Antioxidants 2024, 13(11), 1366; https://doi.org/10.3390/antiox13111366 - 8 Nov 2024
Viewed by 907
Abstract
In this review, we toxicologically assessed the naturally occurring toxin domoic acid. We used the One Health approach because the impact of domoic acid is potentiated by climate change and water pollution on one side, and reflected in animal health, food security, human [...] Read more.
In this review, we toxicologically assessed the naturally occurring toxin domoic acid. We used the One Health approach because the impact of domoic acid is potentiated by climate change and water pollution on one side, and reflected in animal health, food security, human diet, and human health on the other. In a changing environment, algal blooms are more frequent. For domoic acid production, the growth of Pseudo-nitzschia diatoms is of particular interest. They produce this toxin, whose capability of accumulation and biomagnification through the food web impacts other organisms in the ecosystem. Domoic acid targets nervous system receptors inducing amnestic shellfish poisoning, among other less severe health-related problems. However, the impact of domoic acid on non-target cells is rather unknown, so we reviewed the currently available literature on cytogenetic effects on human and animal cells. The results of different studies indicate that domoic acid has the potential to induce early molecular events, such as oxidative imbalance and DNA damage, thus posing an additional threat which needs to be thoroughly addressed and monitored in the future. Full article
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