The Electrochemical Tentacles of Oxidative Stress

A special issue of Antioxidants (ISSN 2076-3921).

Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 2669

Special Issue Editors


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Guest Editor
Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceio, Brazil
Interests: oxidative-stress-based diseases; antioxidants; bioactive plant products; biomarkers, molecular electrochemistry
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Departamento de Química, Universidade Federal do Rio Grande do Norte, Natal, Brazil
Interests: analytical chemistry; electrochemistry; environmental chemistry; water/wastewater treatment; photocatalysis; electrochemical techniques
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue looks at oxidative stress (OS), often known as the red/ox state of biological systems and food, and the source knowledge on it, with an emphasis on the relationship between electrochemistry, life, and antioxidant species. Rapid, easy, and sensitive methods are available from the field of electroanalytical chemistry for determining the redox properties and antioxidant activity of physiologically relevant substances in a wide range of samples.

OS is a relatively novel physiological response concept, recognized in medicine and biology in the last three decades. An imbalance of (pro)oxidants and antioxidants in living organisms is at the root of this phenomenon, which is linked to the fundamental redox reactions that are responsible for health signaling and other essential life activities. Many diseases and disorders have been linked to OS. In fact, a notable rise in electrochemical investigations of OS and quantification of its reductant–oxidant indicators (signaling agents), such as reactive oxygen species and antioxidants, has been demonstrated in recent years.

This Special Issue aims to provide a high-level introduction to the contemporary electrochemical analysis and sensor technologies used to track indicators of OS and antioxidant status in living systems or in lab systems via scientific contributions published by experts in the field. A link between cutting-edge electrochemical study and 21st-century medical diagnostics is also the aim of this Special Issue through a discussion of the promising applications of potentiometric and voltammetric techniques in human health evaluation, antioxidants species, and the redox properties and antioxidant activity of relevant substances.

Prof. Dr. Marília O. F. Goulart
Prof. Dr. Carlos Alberto Martinez Huitle
Guest Editors

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Keywords

  • electrochemistry
  • antioxidant activity
  • oxidative stress
  • redox properties

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Published Papers (1 paper)

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Research

16 pages, 1732 KB  
Article
Electrochemical Measures for Determining the Total Antioxidant Capacity of Açaí Pulp (Euterpe oleracea) at a Glassy Carbon Electrode
by Tabata N. Feijoó, Luis D. Loor-Urgilés, Danyelle M. de Araújo, Elisama V. dos Santos, Marília Oliveira Fonseca Goulart and Carlos A. Martínez-Huitle
Antioxidants 2025, 14(9), 1082; https://doi.org/10.3390/antiox14091082 - 3 Sep 2025
Viewed by 1019
Abstract
Antioxidants, such as flavonoids, are influential secondary metabolites that play a significant role in regulating human health. Açaí, known for its potent antioxidant properties, has gained popularity in the nutritional field. However, there is a need for accurate methods to quantify its antioxidant [...] Read more.
Antioxidants, such as flavonoids, are influential secondary metabolites that play a significant role in regulating human health. Açaí, known for its potent antioxidant properties, has gained popularity in the nutritional field. However, there is a need for accurate methods to quantify its antioxidant capacity. Therefore, the goal of this investigation was to determine the total antioxidant capacity of frozen açaí pulp by applying the concept of the electrochemical quantitative index (EQI) using the cyclic voltammetry technique. The electrochemical response of ethanolic extracts obtained by a nonconventional ultrasound bath was investigated in the anodic region. The results clearly showed redox behavior at +0.37 V and +0.27 V (vs. Ag/AgCl) for the anodic and cathodic peaks, respectively, when evaluated by cyclic voltammetry at a glassy carbon (GC) electrode. By investigating a constant ethanolic extract concentration (0.2%) and analyzing the scan rate and supporting electrolyte effects, it was determined that the frozen açaí pulp extract presented an EQI of about 2.3 µA/V. Similarly, the concept of the EQI was extended to the use of the differential pulse voltammetry profile of a 0.2% ethanolic açaí extract on different supporting electrolytes, which showed that some experimental conditions needed improvement. Still, maintaining pH with a buffer solution in the anodic region is crucial to ensure reproducibility. The antioxidant capacity was also determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical assay to compare the electrochemical results. The Folin–Ciocalteu colorimetric test was applied to determine the total phenolic content of the extract. Full article
(This article belongs to the Special Issue The Electrochemical Tentacles of Oxidative Stress)
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