Oxidative Stress in Lung Diseases

Dear Colleagues,

Oxidative stress plays a pivotal role in both the host defense mechanisms and the pathogenesis and progression of lung injury caused by bacterial, viral or fungal pathogens. This Special Issue "Oxidative Stress in Lung Diseases" aims to explore the intricate mechanisms by which oxidative stress contributes to pulmonary pathology as well as to immune defense mechanisms and to highlight potential therapeutic interventions.

We invite submissions that focus on the molecular and cellular mechanisms by which oxidative stress influences lung diseases. Topics of interest include, but are not limited to, the following:

• Mechanisms of Oxidative Damage: Investigations into how reactive oxygen species (ROS) and reactive nitrogen species (RNS) generated by pathogens or by host immune cells cause cellular and tissue damage in lung diseases such as pneumonia, ARDS, chronic obstructive pulmonary disease (COPD), asthma, idiopathic pulmonary fibrosis (IPF), and lung cancer.
• Antioxidant Defense Systems: Studies on the role of endogenous antioxidants and the therapeutic potential of antioxidant supplementation in mitigating oxidative stress-related lung damage.
• Inflammatory Responses: Research on the interplay between oxidative stress and inflammation, and how this contributes to disease progression and exacerbation in respiratory conditions.
• Biomarkers of Oxidative Stress: Identification and validation of biomarkers for early detection, prognosis, and monitoring of lung diseases accompanied by oxidative stress.
• Therapeutic Approaches: Development and evaluation of novel antioxidants and pharmacological interventions aimed at reducing oxidative stress in lung diseases.
• Environmental and Lifestyle Factors: Analysis of how external factors, such as air pollution, smoking, and diet, influence oxidative stress and lung health.

We welcome original research articles, reviews, and clinical studies that provide insights into oxidative stress mechanisms, novel therapeutic targets, and interventions in the context of lung diseases. This Special Issue aims to foster a comprehensive understanding of oxidative stress in lung diseases and promote the development of innovative treatments to enhance respiratory health.

Prof. Dr. Rudolf Lucas
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• ROS
• RNS
• lung diseases
• antioxidant defense
• respiratory health