Assessing Targets with Multiple Antioxidative Mechanisms of Phytochemicals Using a Poly-Pharmacological Strategy
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: 15 November 2024 | Viewed by 202
Special Issue Editors
Interests: diabetic complications; NASH; IBD; Toll-like receptor signal pathway; innate immunity
Special Issues, Collections and Topics in MDPI journals
Interests: skin aging; whitening; skin barrier; nuclear receptors; atopic dermatitis; NRF2; wound healing
Interests: aging; age-related diseases; skin and skin disorders; cosmeceuticals; nutraceuticals; natural plants; polyphenol; fermentation
Special Issues, Collections and Topics in MDPI journals
Interests: diabetes; obesity; NASH; inflammation; Toll-like receptor signal pathway
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Plant-derived phytochemicals act as antioxidants and have been a productive source of leading compounds for the development of novel medications. Owing to the diversity of phytochemicals, they cover a wide spectrum of therapeutic indications against various oxidative stress-related diseases such as cancer, cardiovascular, autoimmune, and neurological diseases.
The number of young hair loss patients has increased recently. This is because they are exposed to various internal and external stresses. The accumulation of oxidative stress appears in aging phenotypes such as decreased skin elasticity and wrinkles and has been reported to affect skin aging diseases such as vitiligo. To study the various mechanisms of action of phytochemicals in targeting these conditions, there are many difficulties with existing research techniques. In order to understand the poly-pharmacological effects of phytochemicals, much time and effort is required when exclusively using conventional experimental methods. In pursuit of a better understanding of oxidative stress-related diseases, rapid advances have been made in the integration of conventional molecular biological experiments, big biodata analysis, and AI technologies. Therefore, it is possible to develop a deeper understanding of diseases and innovate better treatments through a more integrated approach. An important direction for future investigation is to further optimize integrated phytochemical analytical, molecular biological, systems biological, and network pharmacological attempts to predict multiple targets for treatment. This Special Issue aims to identify molecular targets and mechanisms of phytochemicals for oxidative stress-related diseases through a poly-pharmacological approach.
Dr. Ki Sung Kang
Dr. Su-Nam Kim
Dr. Dong Wook Shin
Dr. Dahae Lee
Guest Editors
Manuscript Submission Information
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Keywords
- phytochemicals
- antioxidants
- systems biology
- oxidative stress
- hair loss
- skin aging
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