Antioxidant and Antidiabetic Activities of Plant Matrices: Methods, Mechanisms, and Translational Relevance
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: 31 March 2026 | Viewed by 21
Special Issue Editor
2. Department of Production Engineering, Wroclaw University of Economics and Business, Komandorska 118/120, 53‑345 Wrocław, Poland
Interests: nutraceuticals and functional foods; medicinal plants; bioactive compounds; HPLC; LC-MS; nutrition; antioxidant agent; prebiotics; probiotics; symbiotics; bioavailability in vitro
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue will focus on the robust assessment of antioxidant and antidiabetic activities across diverse plant matrices, ranging from conventional sources (e.g., Camellia sinensis) to wild and underexplored species. We invite studies that close the gap between in vitro assays and physiological relevance, linking chemistry, processing, delivery systems, and mechanistic endpoints. Plant-derived antioxidants and antidiabetic agents continue to show promise at the interface of redox biology and metabolic health, yet translation from bench to bedside is often hindered by fragmented methodology and limited physiological anchoring. For this Special Issue, we welcome original research articles and critical reviews that integrate chemical assays into cellular and mechanistic results, to form a coherent evidence chain spanning from composition to function. We particularly encourage submissions discussing conventional crops and teas alongside wild, neglected, and underutilized species (NUSs), as well as the valorization of side streams and by-products, to broaden the portfolio of sustainable bioactive sources. Contributions may feature processing and formulation strategies that modulate stability, bioaccessibility, and bioavailability, such as drying technologies, sonication, microwave treatment, fermentation, and food-grade carriers (layer-by-layer systems and hydrogels). We especially encourage method harmonization, transparent reporting (e.g., effect sizes, IC₅₀), and inter-laboratory comparability to improve reproducibility and enable meta-analyses. By showcasing work that couples assays with cellular endpoints (ROS handling, Nrf2/ARE signaling, and mitochondrial function) and antidiabetic mechanisms (e.g., α-glucosidase, α-amylase, DPP-IV, antiglycation), this Special Issue will foster rigorous, mechanism-informed development of plant-based interventions for metabolic health.
Dr. Sabina Lachowicz-Wiśniewska
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antioxidant assays
- antidiabetic activity
- α-glucosidase
- α-amylase
- DPP-IV
- antiglycation/AGEs
- tea (Camellia sinensis)
- wild plants
- neglected and underutilized species (NUS)
- stachys
- root and tuber crops
- ultrasound
- microwave
- bioavailability
- metabolomics
- layer-by-layer
- hydrogels
- alginate
- pectin
- chitosan
- zein
- processing by-products
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