Mitochondrial Oxidative Stress and Inflammation
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 10 February 2025 | Viewed by 1739
Special Issue Editor
2. Department of Physiology and Membrane Biology, University of California, Davis, CA 95616, USA
Interests: antioxidants; cardiovascular diseases; mitochondrial metabolism; muscle contraction; proteasome; proteomics; reactive oxygen species
Special Issue Information
Dear Colleagues,
The main source of reactive oxygen species (ROS) responsible for oxidative stress in cells is mitochondrial respiration. When the excessive formation of ROS overwhelms the intrinsic antioxidant, a condition known as oxidative stress occurs. ROS can have damaging effects on proteins, lipids, and DNA, disrupting mitochondrial function and causing the subsequent development of various disease processes. Mitochondrial oxidative stress has been implicated in a wide variety of diseases including Alzheimer’s disease (AD), cardiovascular disease, and autoimmune type 1 diabetes. Research also suggests that mitochondria play an important role in pro-inflammatory signaling. Likewise, pro-inflammatory mediators may also alter mitochondrial function. Both processes increase mitochondrial oxidative stress, promoting an inflammatory cycle.
As Guest Editors, we invite you to contribute to this Special Issue, where the focus of which will be on the role of mitochondrial oxidative stress and/or inflammation in disease progression and during therapeutic interventions.
Prof. Dr. Aldrin V. Gomes
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- oxidative stress
- mitochondria
- antioxidants
- disease
- inflammation
- mitochondrial oxidative stress
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