Targeting Oxidative Stress to Manage Pain
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: 20 December 2024 | Viewed by 56
Special Issue Editor
Interests: pain; analgesic; anti-inflammatory; pharmacology; mechanisms of chronic pain
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chronic pain is a global health problem in modern society affecting more than 30% of people worldwide according to some studies. The experience of pain seriously affects the patient's daily activities and quality of life, as well as representing a high burden on the healthcare system, not only resulting from the costs of healthcare but also from lost productivity. Regardless of the amount of clinically available analgesic drugs, there is still a gap in the therapeutic management of pain, as even the most widely used analgesics are still ineffective or unsafe for some patients suffering from chronic pain. Given the important role of oxidative stress in the pathogenesis of pain, antioxidants can be allies in pain control. Oxidative stress can lead to peripheral and central sensitization in pain pathways, which is associated with the development of chronic pain. In fact, the therapeutic potential of antioxidants in chronic pain syndromes has been increasingly highlighted.
In this context, the Special Issue “Targeting Oxidative Stress to Manage Pain” invites researchers to contribute original research articles and review articles focused on the studies of antioxidant compounds with analgesic properties or that highlight oxidative stress as a target for the development of analgesic drugs. Topics of interest include the characterization of the pharmacological properties of analgesic antioxidants, covering basic science studies on the mechanisms of action, pharmacokinetic profiles, and adverse effects, in addition to clinical trials. Studies aimed at establishing the role of oxidative stress in the pathophysiology of pain, pointing out the possible therapeutic targets, are also welcome.
Prof. Dr. Cristiane Flora Villarreal
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- chronic pain
- antioxidants
- analgesics
- nociceptive sensitization
