Antioxidants from Food and Food Wastes for Nutraceutical, Pharmaceutical and Cosmetic Fields

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Extraction and Industrial Applications of Antioxidants".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 668

Special Issue Editors


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Guest Editor
Department of Pharmaceutical Sciences, Università del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy
Interests: polyphenols, bioactive compounds, analytical methods, antioxidant activity, food processing, chemometrics, functional ingredients, bioaccessibility

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Guest Editor Assistant
Department of Pharmaceutical Sciences, Università del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy
Interests: dietary fibers; functional foods; food ingredients; polyphenols; antioxidants; food biotechnology

Special Issue Information

Dear Colleagues,

We are pleased to present a new Special Issue on the potential of food and agri-food wastes as sustainable sources of antioxidant compounds. While the potential of antioxidants from natural sources is vast, and their exploitation is now essential in the context of green and circular economies in multiple fields, challenges related to the extraction, characterization, stability, and bioavailability remain.

Antioxidant compounds derived from food and agricultural by-products can play an important role in nutraceutical, pharmaceutical, and cosmetic applications, providing health benefits through their antioxidant, anti-inflammatory, and antimicrobial properties and also developing specific activities. However, their successful use depends on the development of efficient extraction processes and innovative formulations that enhance their efficacy, stability, and bioavailability.

This Special Issue aims to address these challenges by focusing on extraction methods, the development of novel formulations, and sustainable technologies. We encourage you to submit original research and review articles that explore these topics, advance the design of functional ingredients and products, and provide solutions to improve the stability (both during storage and after processing), bioavailability, and delivery of antioxidant compounds from food and related wastes or by-products. Due to the importance of this field, research focused on analytical methods for the characterization of antioxidant compounds and the evaluation of their bioactivity will also be considered.

We look forward to receiving your valuable contributions.

Prof. Dr. Monica Locatelli
Guest Editor

Dr. Vincenzo Disca
Guest Editor Assistant

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • phenolic compounds
  • analytical methods
  • bioactivities
  • green extraction
  • functional ingredients
  • food supplements
  • by-products and up-cycled ingredients
  • nutraceutical
  • cosmetics
  • bioaccessibility

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Published Papers (1 paper)

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Research

14 pages, 2027 KiB  
Article
From Waste to Resource: Exploring Green Approaches for Phenolics Recovery from Olive Leaves
by Paulina Tapia-Quirós, Aina Mir-Cerdà, Mercè Granados, Sonia Sentellas and Javier Saurina
Antioxidants 2025, 14(2), 136; https://doi.org/10.3390/antiox14020136 - 24 Jan 2025
Viewed by 412
Abstract
Waste management presents a significant challenge for agri-food industries, but also an opportunity to recover valuable bioactive compounds, particularly phenolics, aligning with circular economy principles. This study compares the efficacy of conventional solvents and natural deep eutectic solvents (NADES) in extracting polyphenols from [...] Read more.
Waste management presents a significant challenge for agri-food industries, but also an opportunity to recover valuable bioactive compounds, particularly phenolics, aligning with circular economy principles. This study compares the efficacy of conventional solvents and natural deep eutectic solvents (NADES) in extracting polyphenols from olive leaves using the scalable techniques of solid–liquid extraction (SLE) with mechanical stirring and microwave-assisted extraction (MAE). Key factors affecting extraction yield, including solvent composition, time, and temperature were investigated. Extraction efficiency was evaluated by measuring total polyphenol content (TPC) by high-performance liquid chromatography (HPLC), antioxidant capacity (FRAP assay), and individual phenolic compounds, also quantified using HPLC. Additionally, differential pulse voltammetry (DPV) was employed to evaluate the antioxidant quality of the extracts. NADES demonstrated superior extraction performance compared to conventional solvents, with the choline–glycerol system showing the highest efficiency. The combination of MAE and NADES emerged as a green and sustainable alternative to traditional methods, offering improved yield and speed. In contrast, SLE with water or ethanol/water mixtures required extended times or higher temperatures for comparable results but offered easier scalability for industrial applications. Full article
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