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Bioactive Compounds in Algae
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Bioactive Compounds in Algae

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (15 April 2022) | Viewed by 5341

Special Issue Editor

Dr. Sanggil Lee

E-Mail Website
Guest Editor
Department of Food Science and Nutrition, Pukyong National University, Busan 48513, Republic of Korea
Interests: marine bioactive compounds; redox medicine; anti-obesity; molecular nutrition; bioactive compound analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

I would like to kindly invite you to contribute to this Special Issue entitled “Bioactive Compounds in Algae”. This Special Issue aims to cover the latest outstanding discoveries on bioactive compounds derived from algae. Algae are a remarkably diverse group of aquatic plants, ranging from the microscopic microalgae to large seaweeds (macroalgae). They contain a vast array of biologically active compounds, such as peptides, polyunsaturated fatty acids, vitamins, carotenoids, polyphenols, dietary fiber, and polysaccharides. Algae have been used in food, feed, cosmeceutical, nutraceutical, and biofuel production industries.

With the growing interest on bioactive compounds from algae, this Special Issue aims to present some of the most significant and recent research on bioactive compounds derived from macroalgae and microalgae. This issue focuses on a panel of research of algae-derived bioactive compounds, for instance, extraction, identification, potential health-promoting effects, and innovative exploitation and utilization. Both research and review papers are welcome.

Potential topics include but are not limited to:

  • Extraction methodologies for extraction of bioactive compounds from algae;
  • Identification of bioactive compounds from algae;
  • Health-promoting effects of algae-derived compounds;
  • Molecular mechanisms regulated by bioactive compounds from algae.

Prof. Dr. Sanggil Lee
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • algae
  • seaweed
  • microalgae
  • macroalgae
  • bioactive compounds
  • health benefit

Published Papers (2 papers)

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Research

26 pages, 952 KiB  
Article
Microalgae as Potential Sources of Bioactive Compounds for Functional Foods and Pharmaceuticals
by Mélanie Silva, Farah Kamberovic, Sisay Tesema Uota, Ismael-Mohammed Kovan, Carla S. B. Viegas, Dina C. Simes, Katkam N. Gangadhar, João Varela and Luísa Barreira
Appl. Sci. 2022, 12(12), 5877; https://doi.org/10.3390/app12125877 - 9 Jun 2022
Cited by 16 | Viewed by 2883
Abstract
Microalgae are an untapped source of bioactive compounds with various biotechnological applications. Several species are industrially produced and commercialized for the feed or cosmetic industries, however, other applications in the functional food and pharmaceutical markets can be foreseen. In this study, nine industrial/commercial [...] Read more.
Microalgae are an untapped source of bioactive compounds with various biotechnological applications. Several species are industrially produced and commercialized for the feed or cosmetic industries, however, other applications in the functional food and pharmaceutical markets can be foreseen. In this study, nine industrial/commercial species were evaluated for in vitro antioxidant, calcium-chelating, anti-tumoral, and anti-inflammatory activities. The most promising extracts were fractionated yielding several promising fractions namely, of Tetraselmis striata CTP4 with anti-inflammatory activity (99.0 ± 0.8% reduction in TNF-α production in LPS stimulated human macrophages at 50 µg/mL), of Phaeodactylum Tricornutum with cytotoxicity towards cancerous cell lines (IC50 = 22.3 ± 1.8 μg/mL and 27.5 ± 1.6 μg/mL for THP-1 and HepG2, respectively) and of Porphyridium sp. and Skeletonema sp. with good chelating activity for iron, copper and calcium (IC50 = 0.047, 0.272, 0.0663 mg/mL and IC50 = 0.055, 0.240, 0.0850 mg/mL, respectively). These fractions were chemically characterized by GC–MS after derivatization and in all, fatty acids at various degrees of unsaturation were the most abundant compounds. Some of the species under study proved to be potentially valuable sources of antioxidant, metal chelators, anti-tumoral and anti-inflammatory compounds with possible application in the functional food and pharmaceutical industries. Full article
(This article belongs to the Special Issue Bioactive Compounds in Algae)
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12 pages, 2094 KiB  
Article
Effects of UV and Heating on the Stability of Fucoxanthin, Total Phlorotannin and Total Antioxidant Capacities in Saccharina japonica Ethanol Extract and Solvent Fractions
by Suhyeon Baek, Lei Cao, Hyeju Lee, Yoonmi Lee and Sanggil Lee
Appl. Sci. 2021, 11(17), 7831; https://doi.org/10.3390/app11177831 - 25 Aug 2021
Cited by 2 | Viewed by 1686
Abstract
The brown alga Saccharina japonica is widely consumed in Asian countries, and post-harvest drying methods such as sun drying and oven drying are commonly used to extend the shelf life of S. japonica. Thus, the present study analyzed the ethanol extract and [...] Read more.
The brown alga Saccharina japonica is widely consumed in Asian countries, and post-harvest drying methods such as sun drying and oven drying are commonly used to extend the shelf life of S. japonica. Thus, the present study analyzed the ethanol extract and organic solvent fractions of S. japonica to examine the effects of UVA and heating on certain bioactive compounds (fucoxanthin, phlorotannin compounds, and total antioxidants) during the drying process. The fucoxanthin contents in the ethanol extract and different solvent fractions significantly decreased in response to UVA. However, fucoxanthin in the ethanol extract and other fractions showed resistance to thermal treatment. It is noteworthy that the total phlorotannin content (TPC) in the ethanol extract and all fractions showed an approximately 2.5-fold increase upon UVA radiation. The TPC also increased in all samples exposed to high temperatures, except for those in the chloroform fraction. The total antioxidant capacity (TAC) also exhibited significant increases in a pattern similar to the TPC. The findings demonstrate that UVA exposure and heating stimulated the degradation of fucoxanthin while it increased the TPC and TAC in the extract and fractions of S. japonica. Full article
(This article belongs to the Special Issue Bioactive Compounds in Algae)
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