Advances in Thermal Therapy

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 2617

Special Issue Editors


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Guest Editor
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China
Interests: thermal treatment; thermal energy control; bioheat and mass modeling

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Guest Editor
Department of Thermal Science and Energy Engineering, University of Science and Technology Beijing, Beijing, China
Interests: biological heat and mass transfer; blood and lymph flow; delivery of nanomedicine; thermal therapy

Special Issue Information

Dear Colleagues,

Thermal therapy is becoming more and more important in clinical applications as it plays significant role in achieving personalized and precise treatment of human diseases by taking advantages of efficient thermal effects with high safety and low complications. This Special Issue of Bioengineering, entitled “Advances in thermal therapy”, aims to explore new techniques and new findings in thermal therapy or treatments greatly enhanced by thermal energy.

The topics of interest of this Special Issue include, but are not limited to, the following:

  1. Clinical findings of tumor thermal treatment or thermally enhanced treatments;
  2. New findings on thermally enhanced treatments in chemotherapy, radiotherapy, gene therapy, immune therapy, etc.;
  3. New techniques for more accurate delivery of thermal energy.

Prof. Dr. Aili Zhang
Prof. Dr. Kai Yue
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • thermal treatments
  • thermal ablation
  • hyperthermia
  • cryosurgery
  • thermally enhanced treatment

Published Papers (2 papers)

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Research

14 pages, 3691 KiB  
Article
Multiphotonic Ablation and Electro-Capacitive Effects Exhibited by Candida albicans Biofilms
by Jose Alberto Arano-Martinez, José Alejandro Hernández-Benítez, Hilario Martines-Arano, Aída Verónica Rodríguez-Tovar, Martin Trejo-Valdez, Blanca Estela García-Pérez and Carlos Torres-Torres
Bioengineering 2024, 11(4), 333; https://doi.org/10.3390/bioengineering11040333 - 28 Mar 2024
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Abstract
This work reports the modification in the homogeneity of ablation effects with the assistance of nonlinear optical phenomena exhibited by C. albicans ATCC 10231, forming a biofilm. Equivalent optical energies with different levels of intensity were irradiated in comparative samples, and significant changes [...] Read more.
This work reports the modification in the homogeneity of ablation effects with the assistance of nonlinear optical phenomena exhibited by C. albicans ATCC 10231, forming a biofilm. Equivalent optical energies with different levels of intensity were irradiated in comparative samples, and significant changes were observed. Nanosecond pulses provided by an Nd:YAG laser system at a 532 nm wavelength in a single-beam experiment were employed to explore the photodamage and the nonlinear optical transmittance. A nonlinear optical absorption coefficient −2 × 10−6 cm/W was measured in the samples studied. It is reported that multiphotonic interactions can promote more symmetric optical damage derived by faster changes in the evolution of fractional photoenergy transference. The electrochemical response of the sample was studied to further investigate the electronic dynamics dependent on electrical frequency, and an electro-capacitive behavior in the sample was identified. Fractional differential calculations were proposed to describe the thermal transport induced by nanosecond pulses in the fungi media. These results highlight the nonlinear optical effects to be considered as a base for developing photothermally activated phototechnology and high-precision photodamage in biological systems. Full article
(This article belongs to the Special Issue Advances in Thermal Therapy)
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15 pages, 23985 KiB  
Article
Model-Optimizing Radiofrequency Parameters of 3D Finite Element Analysis for Ablation of Benign Thyroid Nodules
by Fabiano Bini, Andrada Pica, Franco Marinozzi, Alessandro Giusti, Andrea Leoncini and Pierpaolo Trimboli
Bioengineering 2023, 10(10), 1210; https://doi.org/10.3390/bioengineering10101210 - 17 Oct 2023
Viewed by 1166
Abstract
Radiofrequency (RF) ablation represents an efficient strategy to reduce the volume of thyroid nodules. In this study, a finite element model was developed with the aim of optimizing RF parameters, e.g., input power and treatment duration, in order to achieve the target volume [...] Read more.
Radiofrequency (RF) ablation represents an efficient strategy to reduce the volume of thyroid nodules. In this study, a finite element model was developed with the aim of optimizing RF parameters, e.g., input power and treatment duration, in order to achieve the target volume reduction rate (VRR) for a thyroid nodule. RF ablation is modelled as a coupled electro-thermal problem wherein the electric field is applied to induce tissue heating. The electric problem is solved with the Laplace equation, the temperature distribution is estimated with the Pennes bioheat equation, and the thermal damage is evaluated using the Arrhenius equation. The optimization model is applied to RF electrode with different active tip lengths in the interval from 5 mm to 40 mm at the 5 mm step. For each case, we also explored the influence of tumour blood perfusion rate on RF ablation outcomes. The model highlights that longer active tips are more efficient as they require lesser power and shorter treatment time to reach the target VRR. Moreover, this condition is characterized by a reduced transversal ablation zone. In addition, a higher blood perfusion increases the heat dispersion, requiring a different combination of RF power and time treatment to achieve the target VRR. The model may contribute to an improvement in patient-specific RF ablation treatment. Full article
(This article belongs to the Special Issue Advances in Thermal Therapy)
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