Neuropathic Pain: Molecular Basis and Translational Research
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 6854
Special Issue Editor
Special Issue Information
Dear Colleagues,
Neuropathic pain triggered by a lesion or disease of the somatosensory nervous system is a common chronic pain disorder with a key impact on quality of life. Examples include postherpetic neuralgia, painful polyneuropathy, trigeminal neuralgia, and central poststroke pain. Most patients complain of current or intermittent spontaneous pain, for example, squeezing quality, burning, and pricking, which may be accompanied by evoked pain. Evoked pain may spread to neighboring areas, and the underlying pathophysiology involves peripheral and central sensitization.
This Special Issue aims to present evidence of the potential targets, therapeutic drugs and nanoformulations, and their mechanisms in treating neuropathic pain disorders. We welcome original research and review papers focused on the mechanism and therapeutic potential of phytochemicals, peptides, and synthetic nanoparticle-based formulations that are engaged in improving neuropathic pain in preclinical and clinical studies. Furthermore, we encourage studies using in vivo and in vitro models to explore the mechanism of action and interaction of nanoformulations with molecular mediators of oxidative/nitrosative stress caused by neuropathic pain conditions.
Specific topics covered by this Special Issue include:
- Basic and applied neuropathic pain research;
- Multidisciplinary neuropathic pain research;
- Neuromodulation;
- Palliative care and pain management;
- Behavioral management of neuropathic pain;
- Drug studies involving neuropathic pain;
- Opioids and NSAIDs;
- Genetics in neuropathic pain;
- Molecular mechanisms of neuropathic pain.
Dr. Gurjit Singh
Guest Editor
Manuscript Submission Information
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Keywords
- neurological disorders
- sensory nerve damage
- peripheral neuropathic pain
- diabetic neuropathy
- post stroke pain
