Artificial Intelligence in Deep Brain Stimulation

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".

Deadline for manuscript submissions: closed (15 June 2023) | Viewed by 3205

Special Issue Editors


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Guest Editor
Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL 32608, USA
Interests: deep brain stimulation; movement disorders; Parkinson’s disease; essential tremor; connectomics; neuroimaging; artificial intelligence; machine learning
Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL 32608, USA
Interests: invasive and noninvasive neuromodulation; neurophysiology; neuroimaging; neurotechnology; movement disorders

Special Issue Information

Dear Colleagues,

The use of deep brain stimulation (DBS) for a variety of neurological and psychiatric disorders is one of the most important advances in clinical neuroscience over the past two decades. DBS enables neuroscientists to obtain direct measures of neuronal activities, interrogate the function of neural circuits, and investigate the therapeutic potential of modulating these circuits with unprecedented spatial and temporal precision. Concurrently, artificial intelligence (AI), especially machine learning, has been increasingly and successfully used in a wide range of healthcare contexts, including DBS. AI methods enable the interpretation of large multimodal datasets and can help to inform DBS candidate selection, surgical targeting, programming optimization, and DBS mechanisms, potentially paving the way for precision neuromodulation. As more data become available and computational power continues to increase, opportunities for the application of AI in DBS are expected to skyrocket.

This Special Issue of Biomedicines, “Artificial Intelligence in Deep Brain Stimulation”, will mainly focus on the recent advances in the application of AI in DBS to contextualize the current body of research and discuss potential future directions. We cordially invite authors to submit original research or review articles pertaining to this important and fast-growing field. The goal is to stimulate research and clinical interests in this exciting field of biomedicine with the hope of developing strategies to integrate artificial intelligence for precision neuromodulation therapy.

Dr. Joshua Wong
Dr. Jun Yu
Guest Editors

Manuscript Submission Information

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Keywords

  • artificial intelligence
  • machine learning
  • deep brain stimulation
  • neuromodulation

Published Papers (1 paper)

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Review

12 pages, 261 KiB  
Review
Discovering Themes in Deep Brain Stimulation Research Using Explainable Artificial Intelligence
by Ben Allen
Biomedicines 2023, 11(3), 771; https://doi.org/10.3390/biomedicines11030771 - 3 Mar 2023
Cited by 2 | Viewed by 2276
Abstract
Deep brain stimulation is a treatment that controls symptoms by changing brain activity. The complexity of how to best treat brain dysfunction with deep brain stimulation has spawned research into artificial intelligence approaches. Machine learning is a subset of artificial intelligence that uses [...] Read more.
Deep brain stimulation is a treatment that controls symptoms by changing brain activity. The complexity of how to best treat brain dysfunction with deep brain stimulation has spawned research into artificial intelligence approaches. Machine learning is a subset of artificial intelligence that uses computers to learn patterns in data and has many healthcare applications, such as an aid in diagnosis, personalized medicine, and clinical decision support. Yet, how machine learning models make decisions is often opaque. The spirit of explainable artificial intelligence is to use machine learning models that produce interpretable solutions. Here, we use topic modeling to synthesize recent literature on explainable artificial intelligence approaches to extracting domain knowledge from machine learning models relevant to deep brain stimulation. The results show that patient classification (i.e., diagnostic models, precision medicine) is the most common problem in deep brain stimulation studies that employ explainable artificial intelligence. Other topics concern attempts to optimize stimulation strategies and the importance of explainable methods. Overall, this review supports the potential for artificial intelligence to revolutionize deep brain stimulation by personalizing stimulation protocols and adapting stimulation in real time. Full article
(This article belongs to the Special Issue Artificial Intelligence in Deep Brain Stimulation)
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