New Advances in Insulin—100 Years Since Its Discovery: 2nd Edition
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 863
Special Issue Editor
2. Medical Faculty, University of Zagreb, Šalata 2, 10000 Zagreb, Croatia
Interests: diabetes type 1; diabetes type 2; metabolic syndrome; diabetic nephropathy; diabetic retinopathy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The discovery of insulin in 1921 represented a milestone in the treatment of diabetes. In 1923, the Nobel Prize for Medicine was awarded for its discovery, and it was one of the most important discoveries in the history of medical science, affecting hundreds of millions of people worldwide. Thousands of lives have been saved, and the life expectancy of people with diabetes has been significantly extended. Since its discovery, insulin has been continuously improved through pharmacological development and optimized for therapeutic purposes, including the development of intermediate- and long-acting insulins, the ability to produce human insulin, and finally, the development of insulin analogs with improved properties using recombinant DNA technology.
Despite increasing awareness, diabetes is still one of the most challenging health problems in the 21st century. In the last 15 years, the number of people diagnosed with type 1 diabetes has increased by 45%, and the number of people diagnosed with type 2 diabetes has increased by 95%. Recently, the focus in the treatment of diabetes has been on new therapeutic options; however, insulin is still one of the most potent therapeutic options for patients with type 2 diabetes and is the only one for patients with type 1 diabetes.
Considering this context, this Special Issue will focus on the roles of insulin and insulin action in a broad sense. We welcome submissions related to new knowledge about insulin secretion and action, as well as the development and action of insulin analogs and their effects on glycemic control and chronic complications in diabetes.
Dr. Tomislav Bulum
Guest Editor
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Keywords
- insulin action
- insulin analogs
- type 1 diabetes
- type 2 diabetes
- complications
- glucose homeostasis
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Related Special Issue
- New Advances in Insulin—100 Years since Its Discovery in Biomedicines (12 articles)
