Advanced Research in Age-Related Macular Degeneration (AMD)
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 22362
Special Issue Editor
Interests: retina; AMD; aging; autophagy; transcriptome; animal model; RPE; oxidative stress; neurodegeneration; Alzheimer’s disease; chloroquine; medical genetics; retinopathy; anti-VEGF; neovascular AMD
Special Issue Information
Dear Colleagues,
Age-related macular degeneration (AMD) is an eye disease that is the main cause of irreversible vision loss in people over 60 years of age. Due to the aging of the global population predicted in the coming decades, the number of patients with AMD is expected to increase significantly. AMD is a disease of a complex nature, the development of which is controlled by many interacting genetic and environmental factors that determine the form, rate of disease progression, and response to therapy.
The pathogenesis of AMD is based on a decrease in metabolic and regenerative processes characteristic of aging, a violation of the microcirculation and structural organization of the retina, the prerequisites and mechanisms for the transition of which into the pathological process remain unclear. Therefore, studies of the molecular mechanisms of AMD pathogenesis and new approaches to its early diagnostics, treatments, and prevention are urgently needed. In this Special Issue of the journal Biomedicines, we would like to invite you to provide original clinical and experimental studies and reviews on all aspects related to the theme of “Advanced Research in AMD”. Submissions dealing with the topics mentioned in the keywords listed below are welcome.
Dr. Oyuna Kozhevnikova
Guest Editor
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Keywords
- dry AMD pathogenesis
- neovascular age-related macular degeneration
- optical coherence tomography and angiography
- anti-VEGF resistance and incomplete response to anti-VEGF therapy
- early diagnosis biomarkers
- biomarkers for predicting treatment response
- lipofusciogenesis and drusogenesis in AMD
- oxidative stress and antioxidant system in AMD
- chronic inflammation and complement system dysregulation in AMD
- AMD genetics: mutations and polymorphisms of genes related to AMD
- epigenetics and miRNA regulation in AMD
- AMD animal and cell models
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