Microbial Metabolites and Their Impact on Gut Homeostasis
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Microbiology in Human Health and Disease".
Deadline for manuscript submissions: 28 February 2025 | Viewed by 53
Special Issue Editors
Interests: inflammatory bowel disease; intestinal inflammation; colorectal cancer; intestinal epithelial barrier; microbiota
Special Issues, Collections and Topics in MDPI journals
Interests: colorectal cancer; immunotherapy; inflammatory bowel diseases; anti-cancer drugs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
A growing body of research pinpoints a significant impact of the gut microbiota on human health and disease due to its ability to influence the intestinal epithelial barrier’s function and the host’s immune response. In particular, the intestinal microbiome, taking advantage of dietary compounds, can produce and release numerous metabolites that play a role in the regulation of host physiology, and some microbial metabolites can even be synthesized by gut microbes. These microbe-related molecules can serve as substrates for metabolic reactions and are crucial in modulating host–microbiota interactions.
In this Special Issue, we will focus on the role of microbial metabolites in gut homeostasis, a fine-tuned balance between the intestinal epithelial barrier, commensals, and host immunity, ensuring the absorption of nutrients and protection against enteric pathogens and xenobiotic substances. We will also discuss these compounds’ potential therapeutic implications in treating intestinal and extra-intestinal disorders.
We invite researchers working on the gut microbiota and the related metabolites to submit original articles or reviews to improve our knowledge of this complex and fascinating field.
Dr. Federica Laudisi
Dr. Carmine Stolfi
Guest Editors
Manuscript Submission Information
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Keywords
- intestinal microbiota
- microbial metabolites
- gut homeostasis
- inflammatory response
- intestinal epithelial barrier
- immune response
- diet
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