Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Noncoding RNAs (ncRNAs): The Role in Gene Regulation and Human Diseases
edited by and
submission deadline 31 Jul 2025 | Viewed by 571 | Submission Open
Keywords: ncRNAs; genomic editing; epigenetics; stem cell biology and regenerative medicine
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
New Trends in Cancer Immunotherapy
edited by Markella Zannikou
submission deadline 31 Jul 2025 | Viewed by 409 | Submission Open
Keywords: tumor microenvironment; cancer vaccines; tumor-infiltrating lymphocytes; combination therapy; BITEs; checkpoint inhibitors; CAR T cell therapy; NK cells; antigen presenting cells; tumor associated antigens
(This special issue belongs to the Section Immunology and Immunotherapy)
Novel Progress in Cancer Immunotherapy
edited by
submission deadline 31 Jul 2025 | Viewed by 387 | Submission Open
Keywords: immune checkpoint blockers; CAR-T; solid tumor; liquid tumor; cancer therapy; immunology
(This special issue belongs to the Section Cancer Biology and Oncology)
New Insights into the Diagnosis and Treatment of Breast Cancer submission deadline 31 Jul 2025 | Viewed by 355 | Submission Open
Keywords: Breast cancer; prognostic; medical imaging; chemotherapy; immunotherapy; diagnostics; screening
(This special issue belongs to the Section Cancer Biology and Oncology)
Recent Advances in Craniofacial Pain and Headaches—Second Edition submission deadline 31 Jul 2025 | Viewed by 330 | Submission Open
Keywords: craniofacial pain; headache; migraine; painful temporomandibular disorders; orofacial pain; biomedical advances; treatment; assessment; innovation
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Immunosuppressive Treatment in Glomerular Diseases
edited by Henry H.L. Wu and Rajkumar Chinnadurai
submission deadline 31 Jul 2025 | Viewed by 329 | Submission Open
Keywords: immunosuppressive treatment; glomerular diseases; nephrology
(This special issue belongs to the Section Immunology and Immunotherapy)
Innate Immunity Orchestration in Lung Health and Diseases, 2nd Edition
edited by
submission deadline 31 Jul 2025 | Viewed by 209 | Submission Open
Keywords: innate immune cells; neutrophils; NETs; NETosis; macrophages; phagocytosis; innate lymphoid cells; epithelial cells; lung inflammation; lung cancer; immunotherapy
(This special issue belongs to the Section Immunology and Immunotherapy)
Advances in Therapeutics for Retinal Degeneration
edited by
submission deadline 31 Jul 2025 | Viewed by 209 | Submission Open
Keywords: neuroinflammation; apoptosis; metabolic and oxidative stress; neuroprotection; molecular and cellular pathways; therapeutic strategies; molecular and cellular targets
(This special issue belongs to the Section Molecular and Translational Medicine)
Microcirculation, Thrombosis, and Inflammation in Peripheral Artery Disease and in the Brain submission deadline 31 Jul 2025 | Viewed by 199 | Submission Open
Keywords: microcirculation; thrombosis; inflammation; peripheral artery disease; brain
(This special issue belongs to the Section Molecular and Translational Medicine)
Role of Microbiota in Colonic Inflammation and Colon Cancer
edited by
submission deadline 31 Jul 2025 | Viewed by 194 | Submission Open
Keywords: microbiota; colon inflammation; colon cancer; molecular mechanism; clinical treatment
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Wound Healing: From Mechanisms to Therapeutic Approaches
edited by
submission deadline 31 Jul 2025 | Viewed by 166 | Submission Open
Keywords: wound healing; acute wounds; chronic wounds; keloids; hypertrophic scar; therapies; photobiomodulation; neuroimmunomodulation
(This special issue belongs to the Section Molecular and Translational Medicine)
Amyloid-β Dynamics and Neurodegeneration: Mechanistic Insights and Therapeutic Strategies
edited by
submission deadline 31 Jul 2025 | Viewed by 150 | Submission Open
Keywords: Alzheimer’ s disease (AD); amyloid-β clearance; brain and periphery; cerebral amyloid angiopathy (CAA)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Pathogenesis and Treatment of Mycobacterium Tuberculosis Infection
edited by Sajid Nadeem
submission deadline 31 Jul 2025 | Viewed by 150 | Submission Open
Keywords: mycobacterium tuberculosis; pathogenesis; host-directed therapy; inflammation; necrosis; innate and adaptive immunity
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Innovations in Nanomedicine for Disease Management
edited by Anna Valentino and
submission deadline 31 Jul 2025 | Viewed by 141 | Submission Open
Keywords: nanomedicine; nanoparticles; smart drug delivery; personalized medicine; minimally invasive treatments; gene therapy; regenerative medicine
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Novel Strategies for Oncogene-Addicted Lung Cancers: Not Rare Anymore submission deadline 31 Jul 2025 | Viewed by 61 | Submission Open
Keywords: target therapy; EMT; biomarkers; cancer mutations; preclinical models
(This special issue belongs to the Section Cancer Biology and Oncology)
Diabetes Mellitus: Pharmacological Innovations and Related Therapeutic Benefits submission deadline 31 Jul 2025 | Viewed by 60 | Submission Open
Keywords: therapy of diabetes mellitus; pharmacological innovations; incretins; GLP-1 receptor agonists; SGLT-2 inhibitors; weight control; diabetes-related cardiovascular risk; non-glycemic benefits of diabetes drugs; diabetes-related technologies; diabetes outcomes
(This special issue belongs to the Section Molecular and Translational Medicine)
New Insights in Hypoxic Response Modulation
edited by Rafał Bartoszewski
submission deadline 31 Jul 2025 | Viewed by 49 | Submission Open
Keywords: hypoxia; oxygen homeostasis; oxidative damage; cell death; ischemic events; stroke; myocardial infarction; tumor microenvironment (TME); noncoding RNA; MicroRNAs; long noncoding RNAs; PiRNA; hypoxia-inducible factors (HIFs); targeted delivery; hypoxic cells; regulatory networks; therapeutic opportunities
(This special issue belongs to the Section Cell Biology and Pathology)
Saving Lives from Myocardial Infarction: Prevention vs. Therapy
edited by Dong Wang
submission deadline 31 Jul 2025 | Viewed by 48 | Submission Open
Keywords: myocardial infarction; molecular markers; AI-powered early detection; wearable devices; ischemia– reperfusion injury; artificial intelligence; ventricular remodeling; fibrosis control; molecular imaging; genomics; transcriptomics; proteomics; metabolomics; MI prevention
(This special issue belongs to the Section Molecular and Translational Medicine)
Animal Models of Neurological Disorders: Where Are We Now? (3rd Edition)
edited by
submission deadline 31 Jul 2025 | Viewed by 34 | Submission Open
Keywords: animal model of neurological disorders; Parkinson’ s disease; Alzheimer’ s disease; epilepsy; seizures; Huntington’ s disease; schizophrenia
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
State-of-the-Art Molecular and Translational Medicine in Japan
edited by
submission deadline 31 Jul 2025 | Viewed by 32 | Submission Open
Keywords: molecular and translational research; targeting inflammatory cytokines; targeted drugs; skin diseases; basic mechanisms; novel therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Advances in Oral Medicine—2nd Edition submission deadline 31 Jul 2025 | Viewed by 32 | Submission Open
Keywords: oral medicine; oral manifestations of systemic conditions; drug-induced lesions; oral pathologies; head and neck cancer; autoimmune; oral lesions; bisphosphonates; systemic pharmacotherapy; infectious diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
The Role of Ion Channels and Transporters in Human Health and Diseases (2nd Edition)
edited by Teresa Soda
submission deadline 31 Jul 2025 | Viewed by 28 | Submission Open
Keywords: ion channels; transporters; ion pumps; voltage-gated channels; ionotropic receptors; TRP channels; store-operated channels; piezo channels; NALCN channels; inositol-1; 4; 5-receptors; ryanodine receptors; two-pore channels; synaptic transmission; channelopathies; neurodegenerative disorders; cardiovascular disorders
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Head and Neck Cancer: Mechanisms, Diagnosis, and Therapeutic Progress
edited by and Hideto Saijo
submission deadline 31 Jul 2025 | Viewed by 17 | Submission Open
Keywords: head and neck cancer; oral cancer; laryngeal cancer; nasopharyngeal cancer; thyroid cancer; diagnostic and treatment strategies
(This special issue belongs to the Section Cancer Biology and Oncology)
Demyelinating Diseases: Pathophysiology and Emerging Therapeutic Targets
edited by Jude Taylor
submission deadline 31 Jul 2025 | Viewed by 14 | Submission Open
Keywords: demyelinating diseases; pathophysiological processes; diagnostic accuracy and predicting disease; emerging strategies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Hepatotoxicity: From Pathology to Novel Therapeutic Approaches (2nd Edition)
edited by
submission deadline 31 Jul 2025 | Viewed by 6 | Submission Open
Keywords: cell death; reactive metabolites; oxidative stress; stress signaling; mitochondria; adaptive immunity; HLA associations; hepatotoxicity; drugs; liver injury; adverse drug reaction; drug-induced autoimmune hepatitis; idiosyncratic-drug-induced liver injury; bile acid; drug-induced cholestasis; hepatotoxins; steatosis; fibrosis
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Gynecologic Oncology
edited by Abdelrahman AlAshqar
submission deadline 31 Jul 2025 | Submission Open
Keywords: advancements; molecular techniques; endometrial cancer; personalized treatment; ovarian cancer; immunotherapy; gynecologic cancer outcomes
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Molecular and Translational Medicine in Poland, 3rd Edition submission deadline 31 Aug 2025 | 5 articles | Viewed by 6926 | Submission Open
Keywords: molecular medicine; molecular mechanisms; disease pathogenesis; genetic variants; gene expression; epigenetics; metabolic disorders; cancer
(This special issue belongs to the Section Molecular and Translational Medicine)
Progress in Cardiovascular Pharmacology submission deadline 31 Aug 2025 | 1 articles | Viewed by 1727 | Submission Open
Keywords: cardiovascular diseases; cardiovascular pharmacology; target therapies; molecular pharmacology; heart failure; preventive cardiology; atherosclerosis
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advances in Cancer Biology and Experimental Anticancer Therapies (2nd Edition)
edited by and
submission deadline 31 Aug 2025 | 1 articles | Viewed by 711 | Submission Open
Keywords: cancer biology; experimental anticancer therapies; immunotherapy; immunotoxins; signalling pathways; targeted therapies
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Immune Cell Biology: Insights from Molecular Perspectives
edited by
submission deadline 31 Aug 2025 | Viewed by 299 | Submission Open
Keywords: immune cell biology; cell signaling cascades; autoimmune disorders; immunoinflammatory pathways; hematological disorders
(This special issue belongs to the Section Cell Biology and Pathology)
Progress in Immunopharmacy
edited by and Shun-Hua Chen
submission deadline 31 Aug 2025 | Viewed by 200 | Submission Open
Keywords: immunopharmacy; immunopharmacology; immunomodulation; pharmacological intervention; immunotherapy; drug– immune system interaction; vaccine development; personalized pharmacotherapy
(This special issue belongs to the Section Immunology and Immunotherapy)
New Trends in Regional Anesthesia and Pain Management
edited by
submission deadline 31 Aug 2025 | Viewed by 23 | Submission Open
Keywords: regional anesthesia; ultrasound-guided/stimulator-guided nerve blocks; novel techniques for motor-sparing neural intervention; continuous catheter infusions; opioid-sparing techniques; perioperative pain management; novel local anesthetics; cadaveric dissection exploring the anatomical knowledge of motor-sparing techniques; modalities (techniques; technologies; or drug regimen) to prolong the effect of local anesthetics; ERAS-related studies; AI applications in regional anesthesia and pain management; innovations and protocols/curriculum regarding regional anesthesia and pain management in the battlefield; studies comparing new technologies/simulation (such as EpiFaith; SPRint PNS system; or CompuFlo) with traditional methods in improving regional anesthesia and pain management; regenerative medicine; nutritional pain medicine; application of bone marrow aspirate concentration or other stem cell components in pain medicine; multidisciplinary/comprehensive care program; transarterial embolization for pain management; joint denervation for pain management
(This special issue belongs to the Section Molecular and Translational Medicine)
Nanoparticle-Labeled Exosomes as Theranostic Agents
edited by Karrer M. Alghazali
submission deadline 31 Aug 2025 | Viewed by 8 | Submission Open
Keywords: exosomes; nanotheranostic agent; nanoparticles; exosome labeling; photothermal therapy; drug delivery vehicle; imaging probe
(This special issue belongs to the Section Cell Biology and Pathology)
Emerging Trends in Malignant Mesothelioma
edited by Yuan Xu
submission deadline 31 Aug 2025 | Viewed by 7 | Submission Open
Keywords: mesothelioma; asbestos; novel therapeutic strategies; treatment resistance; multi-omics analysis
(This special issue belongs to the Section Cancer Biology and Oncology)
Hepato-Pancreato-Biliary Cancers: Pathogenesis, Comorbidities and Therapy Updated submission deadline 30 Sep 2025 | 1 articles | Viewed by 934 | Submission Open
Keywords: liver; bile; cancer; microbiome; pathogenesis; MiRNA; jaundice; disease; therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research on the Role of Biogenic Amines in Physiological and Pathological Conditions submission deadline 30 Sep 2025 | Viewed by 247 | Submission Open
Keywords: biogenic amines; memory; synapse; depression; anxiety; schizophrenia; glioma and neurodegenerative diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Immune Checkpoint Molecules and Cancer Immunotherapy
edited by Zhiyuan Qin and Shujing Liu
submission deadline 30 Sep 2025 | Viewed by 18 | Submission Open
Keywords: immune checkpoint molecules; cancer immunity; tumor immune microenvironment; cancer immunotherapy; biomarkers
(This special issue belongs to the Section Immunology and Immunotherapy)
Unraveling New Horizon in Vascular Diseases: From Pathophysiology to Novel Therapeutic
edited by Miguel A. Ortega and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 419 | Submission Open
Keywords: vascular diseases; artery; venous disease; venous hypertension; heart; lymph; diabetes; surgery; immune system; translational medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Genetic and Molecular Mechanisms of Cardiometabolic Diseases and Cancers—2nd Edition
edited by Tao Wu and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 429 | Submission Open
Keywords: cardiometabolic disease; oncology; comorbidity; genetic pleiotropy; direct genetic effects; indirect genetic effects; parent-of-origin
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
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