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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ferroptosis Pathways in Neurodegenerative and Neuropsychiatric Diseases

edited by Jack T. Rogers

submission deadline 15 Aug 2024 | Viewed by 320 | Submission Open

Keywords: ferroptosis; iron; Alzheimer's disease; Parkinson’ s disease; neurodegenerative diseases treatment; neuropsychiatric diseases; long COVID

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Liquid Biopsy: Latest Insights into the Biological Significance of Circulating Tumor Cells

edited by

Valentina Magri

submission deadline 15 Aug 2024 | Viewed by 225 | Submission Open

Keywords: liquid biopsy; circulating tumor cells; tumor biomarkers; cancer; clinical decision-making process; biology

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms of Cell Death in Cancer Cells: A New Therapeutic Opportunity—2nd Edition

edited by

Adrian-Bogdan Țigu

submission deadline 30 Aug 2024 | 2 articles | Viewed by 1942 | Submission Open

Keywords: cell death; drug repositioning; translational research; oncology; cancer therapy; apoptosis

(This special issue belongs to the Section Cell Biology and Pathology)

Head and Neck Tumors, 3rd Edition

edited by

Silvia Di Agostino

and

Jan B. Vermorken

submission deadline 31 Aug 2024 | 10 articles | Viewed by 13966 | Submission Open

Keywords: head and neck tumors; microenvironment; predictive markers; therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Advanced Research in Arrhythmogenic Cardiomyopathy

edited by

Stephen P. Chelko

submission deadline 31 Aug 2024 | 8 articles | Viewed by 13846 | Submission Open

Keywords: arrhythmogenic cardiomyopathy; myocardial inflammation; desmosome; sudden cardiac death; fibrofatty infiltration; exercise

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Trends in Neurostimulation and Neuromodulation Research

edited by Mayank Gupta and Brittni Levasseur

submission deadline 31 Aug 2024 | 8 articles | Viewed by 11481 | Submission Open

Keywords: neuromodulation; nerve stimulation; neurostimulation waveforms; chronic pain treatment; pathophysiology

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Mechanisms and Novel Therapeutic Approaches for Neurodegenerative Diseases

edited by

Fernando Cardona

submission deadline 31 Aug 2024 | 4 articles | Viewed by 9773 | Submission Open

Keywords: neurodegenerative diseases; cellular mechanisms; molecular mechanisms; neurodegeneration models; protein misfolding; protein aggregation; neuronal death; molecular therapy; cellular therapy; therapeutics; medical chemistry; drug screening

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Pain–Neuroinflammation Dyad: New Therapeutic Strategies or Pharmacological Targets to Counter Them

edited by

Giada Amodeo

and

Silvia Franchi

submission deadline 31 Aug 2024 | 4 articles | Viewed by 9600 | Submission Open

Keywords: chronic pain; neuroinflammation; mood disorders

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Recent Advances in Adipokines—2nd Edition

edited by

Christa Buechler

submission deadline 31 Aug 2024 | 8 articles | Viewed by 9106 | Submission Open

Keywords: adiponectin; receptor; agonist; biomarker; inflammation; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

The Role of Cytokines in Health and Disease: 2nd Edition

edited by

Monika Zajkowska

submission deadline 31 Aug 2024 | 6 articles | Viewed by 8935 | Submission Open

Keywords: cytokine; chemokine; neurodegenerative disease; cancer; inflammatory mediator; diagnosis; biomarker

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Research on Acute Myeloid Leukemia (AML) Volume II

edited by

Michele Gottardi

submission deadline 31 Aug 2024 | 6 articles | Viewed by 7908 | Submission Open

Keywords: acute myeloid leukemia; molecular pathogenesis; novel AML therapies; AML clonal evolution; epigenetic alterations; multi-omics; precision medicine; leukemia stem cell

(This special issue belongs to the Section Molecular and Translational Medicine)

Connections between Diabetes Mellitus, Other Metabolic and Endocrine Dysfunctions and Cardiovascular Pathologies

edited by

Cristina Tudoran

submission deadline 31 Aug 2024 | 8 articles | Viewed by 7835 | Submission Open

Keywords: diabetes mellitus; insulin resistance; metabolic syndrome; obesity; thyroid dysfunction; hormonal alterations; endothelial dysfunction; coronary artery disease; hypertension; peripheric arterial disease

(This special issue belongs to the Section Endocrinology and Metabolism Research)

An Update on Mechanisms and Treatments for Thyroid Cancer in Current Oncology

edited by Zhilong Ai

submission deadline 31 Aug 2024 | 5 articles | Viewed by 7540 | Submission Open

Keywords: thyroid cancer; mechanisms; treatments; biomarkers; precision medicine; infiltration; metastasis

(This special issue belongs to the Section Cancer Biology and Oncology)

Musculoskeletal Regenerative Medicine

edited by

Ashim Gupta

and

Nicola Maffulli

submission deadline 31 Aug 2024 | 5 articles | Viewed by 7048 | Submission Open

Keywords: regenerative medicine; stem cells; exosomes; musculoskeletal injuries; osteoarthritis; bone; cartilage; ligament; tendon; tissue engineering

(This special issue belongs to the Section Cell Biology and Pathology)

Diagnosis, Pathogenesis and Treatment of Muscular Dystrophy

edited by

Manuela Bozzi

submission deadline 31 Aug 2024 | 4 articles | Viewed by 6892 | Submission Open

(This special issue belongs to the Section Molecular and Translational Medicine)

Acute and Chronic Heart Failure: Pathophysiology and New Therapeutic Developments

edited by

Serafino Fazio

and Valentina Mercurio

submission deadline 31 Aug 2024 | 4 articles | Viewed by 6660 | Submission Open

Keywords: heart failure with reduced ejection fraction; heart failure with preserved ejection fraction; pathophysiological novelties; treatment advances; pulmonary arterial hypertension; at-home follow up of patients with heart failure

(This special issue belongs to the Section Molecular and Translational Medicine)

Health-Related Applications of Natural Molecule Derived Structures

edited by

Nurettin Sahiner

submission deadline 31 Aug 2024 | 5 articles | Viewed by 6399 | Submission Open

Keywords: natural therapeutic agents; multifunctional biomaterials based on proteins; enzymes; peptides; amino acids; glucosamines; polyphenolics; and carbohydrates; micro-/nano-/bulk materials; drug delivery systems; targeted therapies; metabolism regulation; ROS-scavenging activity; antibacterial; antifungal; and antiviral; antioxidant; anticancer; biocidal; natural remedy; control release; targeted delivery; natural therapeutics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

NASH and Hepatocellular Carcinoma (HCC)

edited by

Feng He

submission deadline 31 Aug 2024 | 3 articles | Viewed by 6376 | Submission Open

Keywords: NAFLD; NASH; HCC; obesity; inflammation; immunotherapy; stress

(This special issue belongs to the Section Cancer Biology and Oncology)

Skin Fibrosis and Cutaneous Wound Healing

edited by

Noriko Aramaki-Hattori

submission deadline 31 Aug 2024 | 5 articles | Viewed by 6227 | Submission Open

(This special issue belongs to the Section Molecular and Translational Medicine)

Cellular and Pathogenesis Mechanisms in Oral Cancer

edited by

Jun-Ichi Tanuma

submission deadline 31 Aug 2024 | 4 articles | Viewed by 5906 | Submission Open

Keywords: oral carcinogenesis; oral cancer model; OSCC; oral cytology; biomarkers; targeted therapies; precision medicine; bioinformatics

(This special issue belongs to the Section Molecular and Translational Medicine)

Next Generation Cytopathology: Current Status and Future Prospects

edited by

Chien-Chin Chen

submission deadline 31 Aug 2024 | 3 articles | Viewed by 5802 | Submission Open

Keywords: cytology; diagnosis; digital; effusion; fine needle aspiration; machine learning; molecular; next-generation sequencing; rapid onsite; reporting system

(This special issue belongs to the Section Molecular and Translational Medicine)

Cellular Mechanisms of Rheumatoid Arthritis

edited by

Samuel García Pérez

submission deadline 31 Aug 2024 | 1 articles | Viewed by 4477 | Submission Open

Keywords: rheumatoid arthritis; immune cells; fibroblast-like synoviocytes; endothelial cells; osteoclasts; molecular mechanisms; cellular responses

(This special issue belongs to the Section Molecular and Translational Medicine)

Novel Biomarkers and Technologies in the Research and Diagnosis of Human Diseases

edited by

Benjamin M. Liu

submission deadline 31 Aug 2024 | 4 articles | Viewed by 3739 | Submission Open

Keywords: pathology; diseases; biomarkers; diagnosis; novel technologies

(This special issue belongs to the Section Immunology and Immunotherapy)

Two Decades of Progress in the Prevention and Treatment of Colorectal Cancer: From Aspirin to Targeted Therapy

edited by

Manish Tripathi

and

Puneet Vij

submission deadline 31 Aug 2024 | 2 articles | Viewed by 3449 | Submission Open

Keywords: immunotherapy; biomarkers; colorectal cancer; targeted therapies; molecular pathways; resistance; personalized medicine; genomic profiling; chemoprevention

(This special issue belongs to the Section Cancer Biology and Oncology)

Sepsis: Pathophysiology and Early Diagnostics

edited by Alexandros Rovas

submission deadline 31 Aug 2024 | 2 articles | Viewed by 3210 | Submission Open

Keywords: biomarkers; infection; organ dysfunction; endothelial dysfunction; organ dysfunction; glycocalyx; cytokine storm; dysregulated immune response

(This special issue belongs to the Section Immunology and Immunotherapy)

Pancreatitis: Etiology, Pathology, and Treatment

edited by Laura Gaman, Mariana Jinga and Stoian Irina

submission deadline 31 Aug 2024 | 2 articles | Viewed by 3051 | Submission Open

Keywords: acute and chronic pancreatitis; pathophysiology; autoimmunity; novel biomarkers; innovative endoscopic; personalized treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenesis and Treatment of Diabetic Cardiomyopathy

edited by

Óscar Lorenzo

submission deadline 31 Aug 2024 | 2 articles | Viewed by 3008 | Submission Open

Keywords: diabetic cardiomyopathy; molecular mechanisms; risk factors; diagnosis; therapy

(This special issue belongs to the Section Cell Biology and Pathology)

Emerging Viral Infectious Diseases: Immunology, Therapeutics and Prevention in Post Pandemic Era

edited by

Yashavanth Shaan Lakshmanappa

submission deadline 31 Aug 2024 | 1 articles | Viewed by 2940 | Submission Open

(This special issue belongs to the Section Immunology and Immunotherapy)

Oxidative Stress Markers in Cardiomyopathy

edited by

Celina Wojciechowska

Ewa B. Romuk

and Wojciech Jachec

submission deadline 31 Aug 2024 | 2 articles | Viewed by 2833 | Submission Open

Keywords: oxidative stress; redox-related biomarkers; antioxidants; heart failure; cardiomyopathy; toxic cardiomyopathy; heart-rhythm-induced cardiomyopathy; stress-induced cardiomyopathies; peripartum cardiomyopathy; inflammatory cardiomyopathy; infiltrative cardiomyopathy

(This special issue belongs to the Section Molecular and Translational Medicine)

Ischemic Stroke and Myocardial Infarction: Potential Therapeutic Targets and Translational Research

edited by

Macarena Hernández-Jiménez

submission deadline 31 Aug 2024 | 3 articles | Viewed by 2831 | Submission Open

Keywords: stroke; cytoprotection; recanalization; pharmacology

(This special issue belongs to the Section Molecular and Translational Medicine)

Inflammatory Bowel Diseases: New Diagnostic and Therapeutic Approaches

edited by

Maria Manuela Estevinho

and

Fernando Magro

submission deadline 31 Aug 2024 | 2 articles | Viewed by 2635 | Submission Open

Keywords: bowel inflammation; crohn’ s disease; endoscopy; inflammatory bowel disease; targeted therapy; ulcerative colitis

(This special issue belongs to the Section Immunology and Immunotherapy)

Pathophysiological Mechanisms of Parkinson's Disease

edited by Eun-Young Lee

submission deadline 31 Aug 2024 | 3 articles | Viewed by 2523 | Submission Open

Keywords: Parkinson’ s disease; pathogenesis; genetics; molecular correlates; pharmacology; cognitive dysfunctions; Parkinson’ s disease dementia; psychophysiology; EEG; MRI

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

New Challenges in the Study of Diabetes and Related Complications-Pathophysiology, Prevention and Treatment

edited by Jeļizaveta Sokolovska

submission deadline 31 Aug 2024 | 2 articles | Viewed by 2469 | Submission Open

Keywords: diabetes mellitus; glucose variability; complications of diabetes; low-grade inflammation; oxidative stress; anti-oxidative response

(This special issue belongs to the Section Cell Biology and Pathology)

Inflammation and Vascular Biology in Regenerative Medicine

edited by

Bisheng Zhou

and Ruihua Ma

submission deadline 31 Aug 2024 | 1 articles | Viewed by 2325 | Submission Open

Keywords: inflammation; vascular biology; injury; repair; regeneration; immunity; macrophage; endothelial cells; cell signaling

(This special issue belongs to the Section Cell Biology and Pathology)

Emerging Trends in Dental Caries: Insights into Etiology, Risk Factors, and Treatment Strategies

edited by

Hee-Eun Kim

submission deadline 31 Aug 2024 | 3 articles | Viewed by 2148 | Submission Open

Keywords: antimicrobial effect; demineralization; dental caries; dental plaque; oral biofilm; oral disease; oral management; pathogenicity; prevention; remineralization

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Nrf2 at the Crossroads of Molecular Mechanisms in Health and Disease

edited by

Magdalena Paulina Kasprzak

and

Dorota Formanowicz

submission deadline 31 Aug 2024 | 1 articles | Viewed by 2127 | Submission Open

Keywords: NRF2; reductive stress; overexpression; oxidative stress; Keap1; antioxidants

(This special issue belongs to the Section Cell Biology and Pathology)

Xenotransplantation: Targeting Acute Vascular Rejection and Endothelial Activation

edited by Konrad Fischer

submission deadline 31 Aug 2024 | 2 articles | Viewed by 2059 | Submission Open

Keywords: endothelial activation; endothelial protection; thrombotic microangiopathy; glycocalyx; acute vascular rejection

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Perspectives on Breast Cancer and Antibody–Drug Conjugates Treatment: From Bench to Bedside

edited by

Alberto Zambelli

submission deadline 31 Aug 2024 | 1 articles | Viewed by 2043 | Submission Open

Keywords: breast cancer; antibody– drug conjugates (ADCs); mechanisms of action; biomarkers identification; toxicity management; resistance mechanisms; treatment sequence

(This special issue belongs to the Section Cancer Biology and Oncology)

Unraveling the Molecular Mechanisms of Heart and Skeletal Muscle Pathologies

edited by

Marie-Louise Bang

and

Edoardo Malfatti

submission deadline 31 Aug 2024 | 2 articles | Viewed by 1890 | Submission Open

Keywords: cardiomyopathies; skeletal myopathies; molecular basis of cardiac and skeletal pathologies; pre-clinical models; including animal and cell-based models.

(This special issue belongs to the Section Cell Biology and Pathology)

Signaling of Protein Kinases in Development and Disease

edited by

John Zheng Fu

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1677 | Submission Open

Keywords: kinase; phosphorylation; signaling; mutation; mechanism; development; inhibitor; disease

(This special issue belongs to the Section Cell Biology and Pathology)

Advanced Cancer Diagnosis and Treatment: Second Edition

edited by

Takaaki Hirotsu

and Hideshi Ishii

submission deadline 31 Aug 2024 | 3 articles | Viewed by 1650 | Submission Open

Keywords: cancer biology; epigenetics; early detection; diagnosis; biodiagnosis; novel therapeutics; new paradigms

(This special issue belongs to the Section Cancer Biology and Oncology)

Vitamin K and Vitamin D in Health and Disease

edited by

Alexandra M. Crǎciun

and

Ciprian N. Silaghi

submission deadline 31 Aug 2024 | 2 articles | Viewed by 1518 | Submission Open

Keywords: vitamin D; vitamin K; Gla proteins; cardiovascular and renal diseases; metabolic syndrome; diabetes mellitus; chronic and acute inflammation; chronic bowel diseases; cartilage arthritis; rheumatoid arthritis; osteoblasts; bone research; atherosclerosis; lipids; lipoproteins; short-chain fatty acids.

(This special issue belongs to the Section Endocrinology and Metabolism Research)

PD-1/PD-L1 and Immunotherapy

edited by Cole Peters, Fares Nigim and Praveen K. Bommareddy

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1511 | Submission Open

Keywords: programmed cell death protein-1; programmed death ligand-1; PD1/PDL1; immunotherapy; oncolytic virus

(This special issue belongs to the Section Immunology and Immunotherapy)

Cardiac Arrhythmias and Arrhythmogenic Disorders: Technological Frontiers, Drug Development and Future Directions

edited by Siamak Salavatian

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1442 | Submission Open

Keywords: cardiac arrhythmias; arrhythmias diagnostic; arrhythmias therapy; technological frontiers; personalized medicine; biomarkers; neuromodulation; artificial intelligence

(This special issue belongs to the Section Molecular and Translational Medicine)

In Vitro Models of Cardiovascular Diseases and Toxicity

edited by

Federico Vozzi

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1405 | Submission Open

Keywords: cardiovascular diseases; tissue engineering; organ-on-chip; 3D systems; co-cultures; toxicity

(This special issue belongs to the Section Molecular and Translational Medicine)

Photodynamic Therapy (3rd Edition)

edited by

Stefano Bacci

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1396 | Submission Open

Keywords: antimicrobial photodynamic treatment; chronic wounds; inflammatory dermatoses; photobiology photochemistry; photochemotherapy; photosensitizing agents; skin cancer; oral mucosa

(This special issue belongs to the Section Immunology and Immunotherapy)

Gene Delivery and Gene Editing

edited by Kosuke Ishikawa

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1309 | Submission Open

Keywords: gene delivery; gene editing; novel module; transposon; genetic engineering

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Pathophysiology and Treatment of Atopic Dermatitis and Psoriasis, 2nd Edition

edited by

Hyeone Kim

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1284 | Submission Open

Keywords: atopic dermatitis; biomarker endotypes; mutation; next-generation sequencing; phenotypes; psoriasis; transcriptome

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenesis and Treatment of Preeclampsia

edited by Patrizia Vergani and

Valentina Giardini

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1259 | Submission Open

Keywords: preeclampsia; hypertensive disorders of pregnancy; placental dysfunction; endothelial dysfunction; therapy; angiogenic imbalance

(This special issue belongs to the Section Molecular and Translational Medicine)

Pharmaceutical Treatments for Typical CKD Comorbidities

edited by

Annalisa Noce

and

Manuela Di Lauro

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1116 | Submission Open

Keywords: natural bioactive compounds; adjuvant treatment; protein energy wasting; mineral bone disorders; metabolic acidosis; hyperhomocysteinemia; uremic sarcopenia; PLADO diet; anemia in CKD

(This special issue belongs to the Section Molecular and Translational Medicine)

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