Nonalcoholic Fatty Liver Disease: From Molecular Mechanisms to Therapeutic Approaches

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 68

Special Issue Editor

Department of Chemistry and Virginia Tech Center for Drug Discovery, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
Interests: peptides; secondary metabolites; nutraceuticals; interactions between small molecules; enzymes; obesity; cytotoxicity; anti-HIV; analytical methods; LC-MS; NMR
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Special Issue Information

Dear Colleagues,

Nonalcoholic fatty liver disease, or NAFLD, refers to a liver problem that affects human beings who drink little to no alcohol, and it is becoming more common, especially in Middle Eastern and Western countries, with increasing rates of obesity. In recent years, great efforts have been made to investigate the pathogenesis of NAFLD; accordingly, a large quantity of biomolecules (small synthetic molecules, natural products, active peptides, oligonucleotide, etc.) with decent activities have been discovered as promising therapeutics through a variety of mechanisms, such as mitochondrial uncouplers, fibroblast growth factor activators, etc. Therefore, this Special Issue aims to publish submissions covering either the identification of biomolecules with promising therapeutic effects or mechanistic studies of biomolecules targeting NAFLD.

Dr. Yumin Dai
Guest Editor

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Keywords

  • nonalcoholic fatty liver disease (NAFLD)
  • non-alcoholic steatohepatitis (NASH)
  • reactive oxygen species
  • mitochondria
  • lipotoxicity

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Published Papers

This special issue is now open for submission.
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