Liver Damage and Associated Metabolic Disorders

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 195

Special Issue Editor

Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX, USA
Interests: hepatic steatosis; advanced liver injury; insulin resistance; inflammation; dyslipidemia; thermogenesis; alcohol; organ crosstalk

Special Issue Information

Dear Colleagues,

The liver is an essential organ of the body that performs over 500 vital functions. These include removing waste products and foreign substances from the bloodstream, regulating blood sugar levels, and creating essential nutrients. The liver is implicated in many processes, and its failure induces severe consequences for metabolism, immune response, detoxification, and antimicrobial defenses. Metabolic dysfunction-associated fatty liver disease (MAFLD) is one of the most common chronic liver diseases worldwide. The close relationship with epidemic obesity and metabolic abnormalities and the potential progression towards end-stage liver diseases, such as cirrhosis and HCC, make MAFLD an emerging global health problem.

This Special Issue aims to gather original findings and intriguing hypotheses related to liver damage caused by a range of stimuli and associated metabolic disorders, including dyslipidemia, insulin resistance, and chronic inflammation. Research areas may include (but are not limited to) the following: molecular and cellular mechanisms in the pathogenesis of liver damage; genetic and epigenetic factors in liver disease risk; lipid dysregulation in disease initiation and progression; interactions between the liver and other organs in the development of metabolic syndrome; biomarkers; and therapeutic strategies for acute and chronic liver disease.

Both original research articles and reviews are welcome. We look forward to receiving your contributions.

Dr. Lin Jia
Guest Editor

Manuscript Submission Information

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Keywords

  • lipid species
  • lipid metabolism
  • organelle dynamics
  • hepatokines
  • metabolic risk
  • immune responses

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Published Papers

This special issue is now open for submission.
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