Catalytic Receptors and Enzymes Involved in Cell-Signaling and Control
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Enzymology".
Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 4137
Special Issue Editor
Interests: structure-function relationships; structural bioinformatics; structure modeling; ligand binding and function; protein evolution; effects of mutations; EGFR family of tyrosine kinases; integrins; GPCRs; PDR-like family of transcription factors; calcium binding proteins; proteases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Enzymes play a large variety of essential roles in an organism, facilitating the chemical reactions necessary for life’s processes. In this Special Issue, we aim to attract articles from a wide scope of studies that explore, e.g., the structure, biochemical, and biological consequences of enzyme functions in health, disease, and also biotechnological applications. Because of their key biochemical roles and localized binding sites for small molecules and macromolecules, enzymes are often targets of inhibitor drugs in medicine and as tools for probing function. Moreover, regulatory enzymes are frequently subject to somatic mutations, most often innocuous, but some mutations elicit functional changes that significantly alter enzymatic activity and ligand binding, affecting health as well as clinical treatment with pharmaceuticals. We would like to address enzymes that play key roles in regulating cellular processes as part of enzyme-linked receptors, enzymes functioning in post-translational modifications, and enzymes functioning through other controlling and regulatory mechanisms acting on molecular processes and cellular signaling.
Prof. Dr. Mark S. Johnson
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- regulatory enzymes
- enzyme-linked receptors, tyrosine kinase receptor families
- serine/threonine kinases
- post-translational modifications
- enzyme structure, function, somatic mutations, molecular interactions, ligand recognition
