Molecular Mechanisms of Diabetes and Chronic Kidney Disease
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 2951
Special Issue Editors
Interests: chronic kidney disease; diabetes; diabetic kidney disease
Special Issue Information
Dear Colleagues,
Diabetes mellitus has been a leading cause of morbidity and mortality in industrialized societies for several decades. With the recent socioeconomic improvements, nutritional transition and influence of the Western diet and lifestyle, the prevalence of diabetes is rising rapidly in developing countries. It is estimated that nearly half a billion people worldwide live with diabetes, and 80% are in low- and middle-income countries. Meanwhile, chronic kidney disease, characterized by an insidious onset and slow but persistent progression, is becoming increasingly prevalent worldwide. As a common and serious complication of diabetes, diabetic kidney disease is a major contributor to the increasing burden of chronic kidney disease, although other causes may be also at play, such as glomerular diseases, chronic kidney disease of unknown etiology and the transition of acute kidney injury to chronic kidney disease. The molecular mechanisms underlying the pathogenesis and progression of diabetes, diabetic complications and chronic kidney disease are still largely uncertain. As a result, the current clinical treatments for diabetes, diabetic complications and chronic kidney disease, which aim to slow disease progression, have limited use and unsatisfying therapeutic efficacy. It is imperative to further understand the molecular signaling mechanisms and key mediating biomolecules involved in diabetes, diabetic complications and chronic kidney disease, and to develop novel and more effective therapeutic targets, with the ultimate goal of improving patient care and disease outcomes.
This Special Issue, entitled “Molecular Mechanisms of Diabetes and Chronic Kidney Disease”, welcomes the submission of original or review articles covering a broad range of aspects related to diabetes, diabetic complications, and chronic kidney disease with an emphasis on the molecular mechanisms or mediating biomolecules implicated in disease pathophysiology and pathogenesis. This may include experimental, clinical, translational, bioinformatics, systems biology, or basic mechanistic studies.
Dr. Rujun Gong
Dr. Shungang Zhang
Guest Editors
Manuscript Submission Information
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Keywords
- diabetes
- diabetic complications
- diabetic kidney disease
- chronic kidney disease
- retinopathy
- neuropathy
- chronic liver disease
- albuminuria
- cellular signaling
- insulin resistance
- pancreatic islets
- inflammation
- metabolic syndrome
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