New Insights into Cardiovascular Immunology

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".

Deadline for manuscript submissions: 15 June 2025 | Viewed by 3081

Special Issue Editors


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Guest Editor
National Heart and Lung Institute, Imperial College London, London, UK
Interests: myocardial infarction; heart failure; autoimmunity; adaptive immune system; autoantibodies

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Guest Editor
Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Sapin
Interests: autoimmunity; myocarditis; heart failure; microRNAs

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Guest Editor
Department of Medicine, The Karolinska Institute, Stockholm, Sweden
Interests: atherosclerosis; Immune system; lipoproteins

Special Issue Information

Dear Colleagues,

Cardiovascular immunology is a young but rapidly expanding field of research. While inflammation has been understood to be a critical aspect of atherosclerosis for some time, cardiology has only recently realized the critical importance of the immune system to the heart itself. They are entwined in a bidirectional crosstalk, and the border between immunology and cardiology is becoming increasingly blurry. This has sparked new and exciting research endeavours, and significant hope that the first immunomodulatory treatment for cardiology patients will soon see the light of day.

In this Special Issue, we invite contributions on all topics related to cardiovascular immunology that are relevant to the heart. These may include clinical and experimental research on the immunology of cardiac conditions, including ischaemic, infectious and inflammatory/autoimmune heart disease and the role of the immune system in heart failure.

In this Special Issue, we also aim to shine a light on the exciting research happening across the world, and we particularly encourage researchers from underrepresented groups and areas to submit their work.

Dr. Susanne Sattler
Dr. Pilar Martín
Dr. Stephen Malin
Guest Editors

Manuscript Submission Information

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Keywords

  • inflammation
  • autoimmunity
  • atherosclerosis
  • myocarditis
  • heart failure

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Published Papers (1 paper)

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Review

13 pages, 707 KiB  
Review
Emerging Roles for Dendritic Cells in Heart Failure
by Danish Saleh, Rebecca T. L. Jones, Samantha L. Schroth, Edward B. Thorp and Matthew J. Feinstein
Biomolecules 2023, 13(10), 1535; https://doi.org/10.3390/biom13101535 - 17 Oct 2023
Cited by 4 | Viewed by 2491
Abstract
The field of cardio-immunology has emerged from discoveries that define roles for innate and adaptive immune responses associated with myocardial inflammation and heart failure. Dendritic cells (DCs) comprise an important cellular compartment that contributes to systemic immune surveillance at the junction of innate [...] Read more.
The field of cardio-immunology has emerged from discoveries that define roles for innate and adaptive immune responses associated with myocardial inflammation and heart failure. Dendritic cells (DCs) comprise an important cellular compartment that contributes to systemic immune surveillance at the junction of innate and adaptive immunity. Once described as a singular immune subset, we now appreciate that DCs consist of a heterogeneous pool of subpopulations, each with distinct effector functions that can uniquely regulate the acute and chronic inflammatory response. Nevertheless, the cardiovascular-specific context involving DCs in negotiating the biological response to myocardial injury is not well understood. Herein, we review our current understanding of the role of DCs in cardiac inflammation and heart failure, including gaps in knowledge and clinical relevance. Full article
(This article belongs to the Special Issue New Insights into Cardiovascular Immunology)
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