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Journals
Biomolecules
Special Issues
Novel Antimicrobial Strategies for Animal Health
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Novel Antimicrobial Strategies for Animal Health

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 1325

Special Issue Editors

Dr. Anna Aris

E-Mail Website
Guest Editor
Department of Ruminant Production, Institute of Agrifood Research and Technology (IRTA), Caldes de Montbui, Barcelona, Spain
Interests: antimicrobial alternatives; antimicrobial resistance; animal health; infectious disease
Special Issues, Collections and Topics in MDPI journals
Dr. Elena Garcia-Fruitos

E-Mail Website
Guest Editor
Department of Ruminant Production, Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Torre Marimon, 08140 Barcelona, Spain
Interests: antimicrobial alternatives; antimicrobial resistance; animal health; infectious disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Antimicrobial resistance (AMR) is a major global concern leading to increased mortality and morbidity and resulting in severe economic losses. The animal sector inevitably plays a role in global AMR threats due to the present exposure levels of animals to antibiotics and the lack of alternatives. Veterinary use of antibiotics poses a threat to human health because of the possible transfer of resistant bacteria to people. In this context, novel antimicrobial strategies are of extreme importance. Numerous alternatives to antibiotics could be developed for treating specific diseases, including bacteriophages, antibodies, probiotics, antimicrobial peptides, and plant-derived extracts, among others. Studies of novel antimicrobial alternatives in animal species under field conditions will be relevant to allow the prudent use of antibiotics, safeguarding not only animal health but also global health. 

Dr. Anna Aris
Dr. Elena Garcia-Fruitos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial alternatives
  • antimicrobial resistance
  • animal health
  • infectious disease

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Published Papers (1 paper)

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Review

17 pages, 2717 KiB  
Review
Enzymatic Regulation of the Gut Microbiota: Mechanisms and Implications for Host Health
by Zipeng Jiang, Liang Mei, Yuqi Li, Yuguang Guo, Bo Yang, Zhiyi Huang and Yangyuan Li
Biomolecules 2024, 14(12), 1638; https://doi.org/10.3390/biom14121638 - 20 Dec 2024
Viewed by 779
Abstract
The gut microbiota, a complex ecosystem, is vital to host health as it aids digestion, modulates the immune system, influences metabolism, and interacts with the brain-gut axis. Various factors influence the composition of this microbiota. Enzymes, as essential catalysts, actively participate in biochemical [...] Read more.
The gut microbiota, a complex ecosystem, is vital to host health as it aids digestion, modulates the immune system, influences metabolism, and interacts with the brain-gut axis. Various factors influence the composition of this microbiota. Enzymes, as essential catalysts, actively participate in biochemical reactions that have an impact on the gut microbial community, affecting both the microorganisms and the gut environment. Enzymes play an important role in the regulation of the intestinal microbiota, but the interactions between enzymes and microbial communities, as well as the precise mechanisms of enzymes, remain a challenge in scientific research. Enzymes serve both traditional nutritional functions, such as the breakdown of complex substrates into absorbable small molecules, and non-nutritional roles, which encompass antibacterial function, immunomodulation, intestinal health maintenance, and stress reduction, among others. This study categorizes enzymes according to their source and explores the mechanistic principles by which enzymes drive gut microbial activity, including the promotion of microbial proliferation, the direct elimination of harmful microbes, the modulation of bacterial interaction networks, and the reduction in immune stress. A systematic understanding of enzymes in regulating the gut microbiota and the study of their associated molecular mechanisms will facilitate the application of enzymes to precisely regulate the gut microbiota in the future and suggest new therapeutic strategies and dietary recommendations. In conclusion, this review provides a comprehensive overview of the role of enzymes in modulating the gut microbiota. It explores the underlying molecular and cellular mechanisms and discusses the potential applications of enzyme-mediated microbiota regulation for host gut health. Full article
(This article belongs to the Special Issue Novel Antimicrobial Strategies for Animal Health)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Vitamin D3 and Butyrate: Cooperative Induction of Antimicrobial Peptides in Poultry
Authors: Guolong Zhang
Affiliation: Oklahoma State University, Stillwater, OK, USA

Title: in vitro antimicrobial activity of enzymatic drug
Authors: Tomasz M. Karpiński
Affiliation: Poznań University of Medical Sciences

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